Genetic basis for clinical response to CTLA-4 blockade in melanoma A Snyder, V Makarov, T Merghoub, J Yuan, JM Zaretsky, A Desrichard, ... New England Journal of Medicine 371 (23), 2189-2199, 2014 | 4709 | 2014 |
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ... Nature 483 (7390), 479-483, 2012 | 2221 | 2012 |
The mutational landscape of adenoid cystic carcinoma AS Ho, K Kannan, DM Roy, LGT Morris, I Ganly, N Katabi, D Ramaswami, ... Nature genetics 45 (7), 791-798, 2013 | 498 | 2013 |
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ... Nature genetics 45 (3), 253-261, 2013 | 458 | 2013 |
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF DF Quail, OC Olson, P Bhardwaj, LA Walsh, L Akkari, ML Quick, IC Chen, ... Nature cell biology 19 (8), 974-987, 2017 | 269 | 2017 |
Primary tumors induce neutrophil extracellular traps with targetable metastasis-promoting effects RF Rayes, JG Mouhanna, I Nicolau, F Bourdeau, B Giannias, S Rousseau, ... JCI insight 4 (16), 2019 | 236 | 2019 |
Single-cell spatial immune landscapes of primary and metastatic brain tumours E Karimi, MW Yu, SM Maritan, LJM Perus, M Rezanejad, M Sorin, ... Nature 614 (7948), 555-563, 2023 | 207 | 2023 |
Comprehensive molecular characterization of salivary duct carcinoma reveals actionable targets and similarity to apocrine breast cancer MG Dalin, A Desrichard, N Katabi, V Makarov, LA Walsh, KW Lee, ... Clinical cancer research 22 (18), 4623-4633, 2016 | 192 | 2016 |
Driver mutations of cancer epigenomes DM Roy, LA Walsh, TA Chan Protein & cell 5 (4), 265-296, 2014 | 190 | 2014 |
Single-cell spatial landscapes of the lung tumour immune microenvironment M Sorin, M Rezanejad, E Karimi, B Fiset, L Desharnais, LJM Perus, ... Nature 614 (7948), 548-554, 2023 | 187 | 2023 |
Recurrent SERPINB3 and SERPINB4 mutations in patients who respond to anti-CTLA4 immunotherapy N Riaz, JJ Havel, SM Kendall, V Makarov, LA Walsh, A Desrichard, ... Nature genetics 48 (11), 1327-1329, 2016 | 142 | 2016 |
IGF-1 increases invasive potential of MCF 7 breast cancer cells and induces activation of latent TGF-β1 resulting in epithelial to mesenchymal transition LA Walsh, S Damjanovski Cell Communication and Signaling 9, 1-11, 2011 | 133 | 2011 |
Rapamycin suppresses self-renewal and vasculogenic potential of stem cells isolated from infantile hemangioma S Greenberger, S Yuan, LA Walsh, E Boscolo, KT Kang, B Matthews, ... Journal of investigative dermatology 131 (12), 2467-2476, 2011 | 129 | 2011 |
Neutrophil oxidative stress mediates obesity-associated vascular dysfunction and metastatic transmigration SAC McDowell, RBE Luo, A Arabzadeh, S Doré, NC Bennett, V Breton, ... Nature cancer 2 (5), 545-562, 2021 | 112 | 2021 |
An integrated systems biology approach identifies TRIM25 as a key determinant of breast cancer metastasis LA Walsh, MJ Alvarez, EY Sabio, M Reyngold, V Makarov, S Mukherjee, ... Cell reports 20 (7), 1623-1640, 2017 | 106 | 2017 |
Multi-dimensional genomic analysis of myoepithelial carcinoma identifies prevalent oncogenic gene fusions MG Dalin, N Katabi, M Persson, KW Lee, V Makarov, A Desrichard, ... Nature communications 8 (1), 1197, 2017 | 100 | 2017 |
Discoidin domain receptor 2 is a critical regulator of epithelial–mesenchymal transition LA Walsh, A Nawshad, D Medici Matrix Biology 30 (4), 243-247, 2011 | 96 | 2011 |
Microenvironmental heterogeneity in brain malignancies LJM Perus, LA Walsh Frontiers in immunology 10, 2294, 2019 | 94 | 2019 |
Candidate prognostic markers in breast cancer: focus on extracellular proteases and their inhibitors DM Roy, LA Walsh Breast Cancer: Targets and Therapy, 81-91, 2014 | 78 | 2014 |
Integrated genomics for pinpointing survival loci within arm-level somatic copy number alterations DM Roy, LA Walsh, A Desrichard, JT Huse, W Wu, JJ Gao, P Bose, W Lee, ... Cancer cell 29 (5), 737-750, 2016 | 62 | 2016 |