| Tumour exosome integrins determine organotropic metastasis A Hoshino, B Costa-Silva, TL Shen, G Rodrigues, A Hashimoto, ... Nature 527 (7578), 329-335, 2015 | 4969 | 2015 |
| Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET H Peinado, M Alečković, S Lavotshkin, I Matei, B Costa-Silva, ... Nature medicine 18 (6), 883-891, 2012 | 4088 | 2012 |
| VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche RN Kaplan, RD Riba, S Zacharoulis, AH Bramley, L Vincent, C Costa, ... Nature 438 (7069), 820-827, 2005 | 3906 | 2005 |
| Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver B Costa-Silva, NM Aiello, AJ Ocean, S Singh, H Zhang, BK Thakur, ... Nature cell biology 17 (6), 816-826, 2015 | 2804 | 2015 |
| Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth D Lyden, K Hattori, S Dias, C Costa, P Blaikie, L Butros, A Chadburn, ... Nature medicine 7 (11), 1194-1201, 2001 | 2460 | 2001 |
| Recruitment of stem and progenitor cells from the bone marrow niche requires MMP-9 mediated release of kit-ligand B Heissig, K Hattori, S Dias, M Friedrich, B Ferris, NR Hackett, RG Crystal, ... Cell 109 (5), 625-637, 2002 | 2415 | 2002 |
| Therapeutic stem and progenitor cell transplantation for organ vascularization and regeneration S Rafii, D Lyden Nature medicine 9 (6), 702-712, 2003 | 2163 | 2003 |
| Tumor response to radiotherapy regulated by endothelial cell apoptosis M Garcia-Barros, F Paris, C Cordon-Cardo, D Lyden, S Rafii, ... Science 300 (5622), 1155-1159, 2003 | 1927 | 2003 |
| Extracellular vesicles in cancer: cell-to-cell mediators of metastasis A Becker, BK Thakur, JM Weiss, HS Kim, H Peinado, D Lyden Cancer cell 30 (6), 836-848, 2016 | 1858 | 2016 |
| Double-stranded DNA in exosomes: a novel biomarker in cancer detection BK Thakur, H Zhang, A Becker, I Matei, Y Huang, B Costa-Silva, Y Zheng, ... Cell research 24 (6), 766-769, 2014 | 1835 | 2014 |
| Pre-metastatic niches: organ-specific homes for metastases H Peinado, H Zhang, IR Matei, B Costa-Silva, A Hoshino, G Rodrigues, ... Nature Reviews Cancer 17 (5), 302-317, 2017 | 1811 | 2017 |
| The metastatic niche: adapting the foreign soil B Psaila, D Lyden Nature Reviews Cancer 9 (4), 285-293, 2009 | 1589 | 2009 |
| Identification of distinct nanoparticles and subsets of extracellular vesicles by asymmetric flow field-flow fractionation H Zhang, D Freitas, HS Kim, K Fabijanic, Z Li, H Chen, MT Mark, H Molina, ... Nature cell biology 20 (3), 332-343, 2018 | 1554 | 2018 |
| The perivascular niche regulates breast tumour dormancy CM Ghajar, H Peinado, H Mori, IR Matei, KJ Evason, H Brazier, D Almeida, ... Nature cell biology 15 (7), 807-817, 2013 | 1194 | 2013 |
| Id1 and Id3 are required for neurogenesis, angiogenesis and vascularization of tumour xenografts D Lyden, AZ Young, D Zagzag, W Yan, W Gerald, R O'Reilly, BL Bader, ... Nature 401 (6754), 670-677, 1999 | 1174 | 1999 |
| CD133 expression is not restricted to stem cells, and both CD133+ and CD133– metastatic colon cancer cells initiate tumors SV Shmelkov, JM Butler, AT Hooper, A Hormigo, J Kushner, T Milde, ... The Journal of clinical investigation 118 (6), 2111-2120, 2008 | 1165 | 2008 |
| Exosome-mediated metastasis: communication from a distance I Wortzel, S Dror, CM Kenific, D Lyden Developmental cell 49 (3), 347-360, 2019 | 1098 | 2019 |
| Minimal information for studies of extracellular vesicles (MISEV2023): From basic to advanced approaches JA Welsh, DCI Goberdhan, L O'Driscoll, EI Buzas, C Blenkiron, ... Journal of extracellular vesicles 13 (2), e12404, 2024 | 1016 | 2024 |
| Chemokine-mediated interaction of hematopoietic progenitors with the bone marrow vascular niche is required for thrombopoiesis ST Avecilla, K Hattori, B Heissig, R Tejada, F Liao, K Shido, DK Jin, ... Nature medicine 10 (1), 64-71, 2004 | 1004 | 2004 |
| Extracellular vesicle and particle biomarkers define multiple human cancers A Hoshino, HS Kim, L Bojmar, KE Gyan, M Cioffi, J Hernandez, ... Cell 182 (4), 1044-1061. e18, 2020 | 990 | 2020 |
