Comprehensive molecular portraits of invasive lobular breast cancer G Ciriello, ML Gatza, AH Beck, MD Wilkerson, SK Rhie, A Pastore, ... Cell 163 (2), 506-519, 2015 | 1910 | 2015 |
Integrated genomic and molecular characterization of cervical cancer Cancer Genome Atlas Research Network Nature 543 (7645), 378, 2017 | 1196* | 2017 |
Comprehensive and integrated genomic characterization of adult soft tissue sarcomas AJ Lazar, MD McLellan, MH Bailey, CA Miller, EL Appelbaum, MG Cordes, ... Cell 171 (4), 950-965, 2017 | 925 | 2017 |
Integration of gene mutations in risk prognostication for patients receiving first-line immunochemotherapy for follicular lymphoma: a retrospective analysis of a prospective … A Pastore, V Jurinovic, R Kridel, E Hoster, AM Staiger, M Szczepanowski, ... The lancet oncology 16 (9), 1111-1122, 2015 | 708 | 2015 |
Ibrutinib unmasks critical role of Bruton tyrosine kinase in primary CNS lymphoma C Grommes, A Pastore, N Palaskas, SS Tang, C Campos, D Schartz, ... Cancer discovery 7 (9), 1018-1029, 2017 | 394 | 2017 |
Modulation of splicing catalysis for therapeutic targeting of leukemia with mutations in genes encoding spliceosomal proteins SCW Lee, H Dvinge, E Kim, H Cho, JB Micol, YR Chung, BH Durham, ... Nature medicine 22 (6), 672-678, 2016 | 393 | 2016 |
Lactose drives Enterococcus expansion to promote graft-versus-host disease CK Stein-Thoeringer, KB Nichols, A Lazrak, MD Docampo, ... Science 366 (6469), 1143-1149, 2019 | 303 | 2019 |
Targeting an RNA-binding protein network in acute myeloid leukemia E Wang, SX Lu, A Pastore, X Chen, J Imig, SCW Lee, K Hockemeyer, ... Cancer cell 35 (3), 369-384. e7, 2019 | 299 | 2019 |
Somatic mutations and cell identity linked by Genotyping of Transcriptomes AS Nam, KT Kim, R Chaligne, F Izzo, C Ang, J Taylor, RM Myers, ... Nature 571 (7765), 355-360, 2019 | 292 | 2019 |
Epigenetic evolution and lineage histories of chronic lymphocytic leukaemia F Gaiti, R Chaligne, H Gu, RM Brand, S Kothen-Hill, RC Schulman, ... Nature 569 (7757), 576-580, 2019 | 250 | 2019 |
Synthetic lethal and convergent biological effects of cancer-associated spliceosomal gene mutations SCW Lee, K North, E Kim, E Jang, E Obeng, SX Lu, B Liu, D Inoue, ... Cancer cell 34 (2), 225-241. e8, 2018 | 232 | 2018 |
Localization of a susceptibility gene for familial nonmedullary thyroid carcinoma to chromosome 2q21 JD McKay, F Lesueur, L Jonard, A Pastore, J Williamson, L Hoffman, ... The American Journal of Human Genetics 69 (2), 440-446, 2001 | 224 | 2001 |
Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, ... Nature 574 (7777), 273-277, 2019 | 209 | 2019 |
A somatic mutation in erythro-myeloid progenitors causes neurodegenerative disease E Mass, CE Jacome-Galarza, T Blank, T Lazarov, BH Durham, N Ozkaya, ... Nature 549 (7672), 389-393, 2017 | 200 | 2017 |
Improved prediction of immune checkpoint blockade efficacy across multiple cancer types D Chowell, SK Yoo, C Valero, A Pastore, C Krishna, M Lee, D Hoen, ... Nature biotechnology 40 (4), 499-506, 2022 | 195 | 2022 |
Activating mutations in CSF1R and additional receptor tyrosine kinases in histiocytic neoplasms BH Durham, E Lopez Rodrigo, J Picarsic, D Abramson, V Rotemberg, ... Nature medicine 25 (12), 1839-1842, 2019 | 177 | 2019 |
Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, ... Journal of Experimental Medicine 215 (6), 1729-1747, 2018 | 156 | 2018 |
Altered RNA splicing by mutant p53 activates oncogenic RAS signaling in pancreatic cancer LF Escobar-Hoyos, A Penson, R Kannan, H Cho, CH Pan, RK Singh, ... Cancer cell 38 (2), 198-211. e8, 2020 | 152 | 2020 |
KMT2C mediates the estrogen dependence of breast cancer through regulation of ERα enhancer function K Gala, Q Li, A Sinha, P Razavi, M Dorso, F Sanchez-Vega, YR Chung, ... Oncogene 37 (34), 4692-4710, 2018 | 133 | 2018 |
3’UTR mediated regulation of the cyclin D1 proto-oncogene A Deshpande, A Pastore, AJ Deshpande, Y Zimmermann, G Hutter, ... Cell Cycle 8 (21), 3592-3600, 2009 | 120 | 2009 |