Human sulfotransferases and their role in chemical metabolism N Gamage, A Barnett, N Hempel, RG Duggleby, KF Windmill, JL Martin, ... Toxicological sciences 90 (1), 5-22, 2006 | 843 | 2006 |
A nonlinear regression program for small computers RG Duggleby Analytical Biochemistry 110 (1), 9-18, 1981 | 687 | 1981 |
Acetohydroxyacid synthase RG Duggleby, SS Pang Journal of biochemistry and molecular biology 33 (1), 1-36, 2000 | 499 | 2000 |
Herbicide-binding sites revealed in the structure of plant acetohydroxyacid synthase JA McCourt, SS Pang, J King-Scott, LW Guddat, RG Duggleby Proceedings of the National Academy of Sciences 103 (3), 569-573, 2006 | 471 | 2006 |
Structure and mechanism of inhibition of plant acetohydroxyacid synthase RG Duggleby, JA McCourt, LW Guddat Plant Physiology and Biochemistry 46 (3), 309-324, 2008 | 429 | 2008 |
Regression analysis of nonlinear Arrhenius plots: an empirical model and a computer program RG Duggleby Computers in biology and medicine 14 (4), 447-455, 1984 | 386 | 1984 |
Properties and functions of the thiamin diphosphate dependent enzyme transketolase G Schenk, RG Duggleby, PF Nixon The international journal of biochemistry & cell biology 30 (12), 1297-1318, 1998 | 312 | 1998 |
Methotrexate, a high-affinity pseudosubstrate of dihydrofolate reductase JW Williams, JF Morrison, RG Duggleby Biochemistry 18 (12), 2567-2573, 1979 | 293 | 1979 |
Acetohydroxyacid synthase and its role in the biosynthetic pathway for branched-chain amino acids JA McCourt, RG Duggleby Amino acids 31, 173-210, 2006 | 276 | 2006 |
Crystal structure of yeast acetohydroxyacid synthase: a target for herbicidal inhibitors SS Pang, RG Duggleby, LW Guddat Journal of molecular biology 317 (2), 249-262, 2002 | 270 | 2002 |
[3] Analysis of enzyme progress curves by nonlinear regression RG Duggleby Methods in Enzymology 249, 61-90, 1995 | 243 | 1995 |
Molecular basis of sulfonylurea herbicide inhibition of acetohydroxyacid synthase SS Pang, LW Guddat, RG Duggleby Journal of Biological Chemistry 278 (9), 7639-7644, 2003 | 235 | 2003 |
Structure of a human carcinogen-converting enzyme, SULT1A1: structural and kinetic implications of substrate inhibition NU Gamage, RG Duggleby, AC Barnett, M Tresillian, CF Latham, ... Journal of Biological Chemistry 278 (9), 7655-7662, 2003 | 197 | 2003 |
NMR analysis of covalent intermediates in thiamin diphosphate enzymes K Tittmann, R Golbik, K Uhlemann, L Khailova, G Schneider, M Patel, ... Biochemistry 42 (26), 7885-7891, 2003 | 165 | 2003 |
[6] Kinetics of slow and tight-binding inhibitors SE Szedlacsek, RG Duggleby Methods in enzymology 249, 144-180, 1995 | 155 | 1995 |
Herbicide-resistant forms of Arabidopsis thaliana acetohydroxyacid synthase: characterization of the catalytic properties and sensitivity to inhibitors of four defined mutants AK Chang, RG DUGGLEBY Biochemical Journal 333 (3), 765-777, 1998 | 154 | 1998 |
The structure of human SULT1A1 crystallized with estradiol: an insight into active site plasticity and substrate inhibition with multi-ring substrates NU Gamage, S Tsvetanov, RG Duggleby, ME McManus, JL Martin Journal of Biological Chemistry 280 (50), 41482-41486, 2005 | 146 | 2005 |
Parameter estimation using a direct solution of the integrated Michaelis-Menten equation CT Goudar, JR Sonnad, RG Duggleby Biochimica et Biophysica Acta (BBA)-Protein Structure and Molecular …, 1999 | 145 | 1999 |
Elucidating the specificity of binding of sulfonylurea herbicides to acetohydroxyacid synthase JA McCourt, SS Pang, LW Guddat, RG Duggleby Biochemistry 44 (7), 2330-2338, 2005 | 140 | 2005 |
Systematic characterization of mutations in yeast acetohydroxyacid synthase: interpretation of herbicide‐resistance data RG Duggleby, SS Pang, H Yu, LW Guddat European Journal of Biochemistry 270 (13), 2895-2904, 2003 | 138 | 2003 |