Structures of rhodopsin in complex with G-protein-coupled receptor kinase 1 Q Chen, M Plasencia, Z Li, S Mukherjee, D Patra, CL Chen, T Klose, ... Nature 595 (7868), 600-605, 2021 | 110 | 2021 |
Cryo-EM structures of eastern equine encephalitis virus reveal mechanisms of virus disassembly and antibody neutralization SS Hasan, C Sun, AS Kim, Y Watanabe, CL Chen, T Klose, G Buda, ... Cell reports 25 (11), 3136-3147. e5, 2018 | 61 | 2018 |
Cryo-EM structure of eastern equine encephalitis virus in complex with heparan sulfate analogues CL Chen, SS Hasan, T Klose, Y Sun, G Buda, C Sun, WB Klimstra, ... Proceedings of the National Academy of Sciences 117 (16), 8890-8899, 2020 | 28 | 2020 |
Solution structure and backbone dynamics of streptopain CC Wang, HC Houng, CL Chen, PJ Wang, CF Kuo, YS Lin, JJ Wu, MT Lin, ... Journal of Biological Chemistry 284 (16), 10957-10967, 2009 | 26 | 2009 |
Visualizing the enzyme mechanism of mevalonate diphosphate decarboxylase CL Chen, LN Paul, JC Mermoud, CN Steussy, CV Stauffacher Nature Communications 11 (1), 3969, 2020 | 18 | 2020 |
Mevalonate 5-diphosphate mediates ATP binding to the mevalonate diphosphate decarboxylase from the bacterial pathogen Enterococcus faecalis CL Chen, JC Mermoud, LN Paul, CN Steussy, CV Stauffacher Journal of Biological Chemistry 292 (52), 21340-21351, 2017 | 12 | 2017 |
Structural/functional studies of Trio provide insights into its configuration and show that conserved linker elements enhance its activity for Rac1 SJ Bandekar, CL Chen, SK Ravala, JN Cash, LV Avramova, MV Zhalnina, ... Journal of Biological Chemistry 298 (8), 102209, 2022 | 7 | 2022 |
Cryo-EM structures of alphavirus conformational intermediates in low pH–triggered prefusion states CL Chen, T Klose, C Sun, AS Kim, G Buda, MG Rossmann, MS Diamond, ... Proceedings of the National Academy of Sciences 119 (30), e2114119119, 2022 | 7 | 2022 |
Molecular basis for Gβγ-mediated activation of phosphoinositide 3-kinase γ CL Chen, R Syahirah, SK Ravala, YC Yen, T Klose, Q Deng, JJG Tesmer Nature structural & molecular biology 31 (8), 1198-1207, 2024 | 6 | 2024 |
Structure of adenylyl cyclase 5 in complex with Gβγ offers insights into ADCY5-related dyskinesia YC Yen, Y Li, CL Chen, T Klose, VJ Watts, CW Dessauer, JJG Tesmer Nature structural & molecular biology 31 (8), 1189-1197, 2024 | 4 | 2024 |
Isoform specific regulation of adenylyl cyclase 5 by Gβγ YC Yen, Y Li, CL Chen, T Klose, VJ Watts, CW Dessauer, JJG Tesmer bioRxiv, 2023 | 3 | 2023 |
Structural and dynamic changes in P-Rex1 upon activation by PIP3 and inhibition by IP4 SK Ravala, SR Adame-Garcia, S Li, CL Chen, MA Cianfrocco, JS Gutkind, ... Elife 12, RP92822, 2024 | 1 | 2024 |
Structural Dynamics in RhoGEF Signaling Investigated Using Model Cell Membranes J Cash, S Ravala, SR Adame-Garcia, S Li, CL Chen, M Cianfrocco, ... The Journal of Pharmacology and Experimental Therapeutics 389, 367, 2024 | | 2024 |
Structural dynamics in RhoGEF signaling investigated using model cell membranes S Ravala, S Adame-Garcia, S Li, CL Chen, MA Cianfrocco, JS Gutkind, ... Biophysical Journal 123 (3), 152a, 2024 | | 2024 |
Structural and Mechanistic Basis for Gbetagamma-mediated Activation of Phosphoinositide 3-kinase-gamma CL Chen, S Ravala, YC Yen, T Klose, R Syahirah, JJG Tesmer, Q Deng The Journal of Pharmacology and Experimental Therapeutics 385, 235, 2023 | | 2023 |
New insights into regulation of P‐Rex1 autoinhibition SK Ravala, S Li, CL Chen, MA Cianfrocco, JN Cash, JJG Tesmer The FASEB Journal 36, 2022 | | 2022 |
Structural Insights into Entry and Antibody Neutralization of Eastern Equine Encephalitis Virus SS Hasan, C Sun, A Kim, Y Watanabe, CL Chen, T Klose, G Buda, ... Biophysical Journal 116 (3), 576a, 2019 | | 2019 |
Substrate‐induced Structural Changes in the Mevalonate Diphosphate Decarboxylase from Enterococcus faecalis CL Chen The FASEB Journal 30, 1083.23-1083.23, 2016 | | 2016 |
Functional and structural characterization of the mevalonate diphosphate decarboxylase and the isopentenyl diphosphate isomerase from Enterococcus faecalis CL Chen Purdue University, 2016 | | 2016 |