| The seco-iridoid pathway from Catharanthus roseus K Miettinen, L Dong, N Navrot, T Schneider, V Burlat, J Pollier, L Woittiez, ... Nature communications 5 (1), 3606, 2014 | 504 | 2014 |
| The bHLH transcription factor BIS1 controls the iridoid branch of the monoterpenoid indole alkaloid pathway in Catharanthus roseus A Van Moerkercke, P Steensma, F Schweizer, J Pollier, I Gariboldi, ... Proceedings of the National Academy of Sciences 112 (26), 8130-8135, 2015 | 215 | 2015 |
| A translational synthetic biology platform for rapid access to gram-scale quantities of novel drug-like molecules J Reed, MJ Stephenson, K Miettinen, B Brouwer, A Leveau, P Brett, ... Metabolic Engineering 42, 185-193, 2017 | 192 | 2017 |
| The ancient CYP716 family is a major contributor to the diversification of eudicot triterpenoid biosynthesis K Miettinen, J Pollier, D Buyst, P Arendt, R Csuk, S Sommerwerk, T Moses, ... Nature communications 8 (1), 14153, 2017 | 183 | 2017 |
| An endoplasmic reticulum-engineered yeast platform for overproduction of triterpenoids P Arendt, K Miettinen, J Pollier, R De Rycke, N Callewaert, A Goossens Metabolic engineering 40, 165-175, 2017 | 172 | 2017 |
| Characterization of the plastidial geraniol synthase from Madagascar periwinkle which initiates the monoterpenoid branch of the alkaloid pathway in internal phloem associated … AJ Simkin, K Miettinen, P Claudel, V Burlat, G Guirimand, V Courdavault, ... Phytochemistry 85, 36-43, 2013 | 171 | 2013 |
| The basic helix‐loop‐helix transcription factor BIS2 is essential for monoterpenoid indole alkaloid production in the medicinal plant Catharanthus roseus A Van Moerkercke, P Steensma, I Gariboldi, J Espoz, PC Purnama, ... The Plant Journal 88 (1), 3-12, 2016 | 123 | 2016 |
| Characterization of two geraniol synthases from Valeriana officinalis and Lippia dulcis: similar activity but difference in subcellular localization L Dong, K Miettinen, M Goedbloed, FWA Verstappen, A Voster, ... Metabolic engineering 20, 198-211, 2013 | 105 | 2013 |
| Iridoid synthase activity is common among the plant progesterone 5β-reductase family J Munkert, J Pollier, K Miettinen, A Van Moerkercke, R Payne, F Müller-Uri, ... Molecular plant 8 (1), 136-152, 2015 | 89 | 2015 |
| The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis K Miettinen, S Inigo, L Kreft, J Pollier, C De Bo, A Botzki, F Coppens, ... Nucleic acids research 46 (D1), D586-D594, 2018 | 65 | 2018 |
| Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol NL Hansen, K Miettinen, Y Zhao, C Ignea, A Andreadelli, MH Raadam, ... Microbial cell factories 19, 1-17, 2020 | 44 | 2020 |
| A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination K Miettinen, N Leelahakorn, A Almeida, Y Zhao, LR Hansen, ... Nature communications 13 (1), 3664, 2022 | 41 | 2022 |
| Expanding the terpene biosynthetic code with non-canonical 16 carbon atom building blocks C Ignea, MH Raadam, A Koutsaviti, Y Zhao, YT Duan, M Harizani, ... Nature Communications 13 (1), 5188, 2022 | 40 | 2022 |
| Integrated metabolomics identifies CYP72A67 and CYP72A68 oxidases in the biosynthesis of Medicago truncatula oleanate sapogenins V Tzin, JH Snyder, DS Yang, DV Huhman, BS Watson, SN Allen, Y Tang, ... Metabolomics 15, 1-20, 2019 | 31 | 2019 |
| Metabolic alteration of Catharanthus roseus cell suspension cultures overexpressing geraniol synthase in the plastids or cytosol MZ Saiman, K Miettinen, NR Mustafa, YH Choi, R Verpoorte, AE Schulte Plant Cell, Tissue and Organ Culture (PCTOC) 134, 41-53, 2018 | 30 | 2018 |
| Biosynthesis and biotechnological production of the anti-obesity agent celastrol Y Zhao, NL Hansen, YT Duan, M Prasad, MS Motawia, BL Møller, ... Nature Chemistry 15 (9), 1236-1246, 2023 | 26 | 2023 |
| An Independent Evolutionary Origin for Insect Deterrent Cucurbitacins in Iberis amara L Dong, A Almeida, J Pollier, B Khakimov, JE Bassard, K Miettinen, ... Molecular Biology and evolution 38 (11), 4659-4673, 2021 | 14 | 2021 |
| Elucidation of the secoiridoid pathway in Catharanthus roseus K Miettinen Chem. Pharm. Bull.(Tokyo) 55, 159-222, 2007 | 4 | 2007 |
| Structure‐Agnostic Bioactivity‐Driven Combinatorial Biosynthesis Reveals New Antidiabetic and Anticancer Triterpenoids Y Zhao, YT Duan, J Zang, MH Raadam, I Pateraki, K Miettinen, D Staerk, ... Angewandte Chemie 137 (4), e202416218, 2025 | 1 | 2025 |
| Celastrol: A century-long journey from the isolation to the biotechnological production and the development of an antiobesity drug Y Zhao, K Miettinen, SC Kampranis Current Opinion in Plant Biology 81, 102615, 2024 | 1 | 2024 |
