Chromatin states define tumour-specific T cell dysfunction and reprogramming M Philip, L Fairchild, L Sun, EL Horste, S Camara, M Shakiba, AC Scott, ... Nature 545 (7655), 452-456, 2017 | 898 | 2017 |
Prediction of potent shRNAs with a sequential classification algorithm R Pelossof, L Fairchild, CH Huang, C Widmer, VT Sreedharan, N Sinha, ... Nature biotechnology 35 (4), 350-353, 2017 | 181 | 2017 |
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia G Minuesa, SK Albanese, W Xie, Y Kazansky, D Worroll, A Chow, ... Nature communications 10 (1), 2691, 2019 | 139 | 2019 |
IKZF2 drives leukemia stem cell self-renewal and inhibits myeloid differentiation SM Park, H Cho, AM Thornton, TS Barlowe, T Chou, S Chhangawala, ... Cell stem cell 24 (1), 153-165. e7, 2019 | 88 | 2019 |
Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma A Verma, Y Jiang, W Du, L Fairchild, A Melnick, O Elemento Genome medicine 7, 1-17, 2015 | 80 | 2015 |
Clonal hematopoiesis detection in patients with cancer using cell-free DNA sequencing L Fairchild, J Whalen, K D’Aco, J Wu, CB Gustafson, N Solovieff, F Su, ... Science Translational Medicine 15 (689), eabm8729, 2023 | 15 | 2023 |
Integrated genomic profiling identifies micro RNA‐92a regulation of IQGAP 2 in locally advanced rectal cancer R Pelossof, OS Chow, L Fairchild, JJ Smith, M Setty, CT Chen, Z Chen, ... Genes, Chromosomes and Cancer 55 (4), 311-321, 2016 | 14 | 2016 |
MA06. 03 KontRASt-01: Preliminary Safety and Efficacy of JDQ443+ TNO155 in Patients with Advanced, KRAS G12C-Mutated Solid Tumors MV Negrao, PA Cassier, B Solomon, M Schuler, K Rohrberg, S Cresta, ... Journal of Thoracic Oncology 18 (11), S117-S118, 2023 | 11 | 2023 |
KRAS mutant rectal cancer cells interact with surrounding fibroblasts to deplete the extracellular matrix JK Kim, MR Marco, SH Choi, X Qu, CT Chen, M Elkabets, L Fairchild, ... Molecular Oncology 15 (10), 2766-2781, 2021 | 7 | 2021 |
Capmatinib in MET exon 14-mutated non-small-cell lung cancer: final results from the open-label, phase 2 GEOMETRY mono-1 trial J Wolf, M Hochmair, JY Han, N Reguart, PJ Souquet, EF Smit, SV Orlov, ... The Lancet Oncology 25 (10), 1357-1370, 2024 | 6 | 2024 |
The oncogenic PI3K-induced transcriptomic landscape reveals key functions in splicing and gene expression regulation E Ladewig, F Michelini, K Jhaveri, P Castel, J Carmona, L Fairchild, ... Cancer research 82 (12), 2269-2280, 2022 | 6 | 2022 |
B11 Accurate Detection of METex14 Mutations in Non-Small Cell Lung Cancer (NSCLC) with Comprehensive Genomic Sequencing: Results from the GEOMETRY Mono-1 Study RS Heist, EB Garon, DSW Tan, HJM Groen, T Seto, EF Smit, N Nwana, ... Journal of Thoracic Oncology 15 (2), S30-S31, 2020 | 6 | 2020 |
Capmatinib (INC280) in patients (pts) with METex14-mutated advances NSCLC: an update from phase 2 GEOMETRY mono-1 study J Wolf, T Seto, JY Han, N Reguart, EB Garon, HJ Groen, DSW Tan, T Hida, ... Pneumologie 74 (S 01), P436, 2020 | 4 | 2020 |
Abstract A029: Biomarker analysis of patients with METΔex14 mutated non-small-cell lung cancer (NSCLC) treated with capmatinib in the GEOMETRY mono-1 study RS Heist, EB Garon, DSW Tan, HJM Groen, T Seto, EF Smit, L Fairchild, ... Molecular Cancer Therapeutics 18 (12_Supplement), A029-A029, 2019 | 4 | 2019 |
A phase Ib/II trial of capmatinib plus spartalizumab vs. spartalizumab alone in patients with pretreated hepatocellular carcinoma A Santoro, E Assenat, T Yau, JP Delord, M Maur, J Knox, S Cattan, ... JHEP Reports 6 (4), 101021, 2024 | 3 | 2024 |
Capmatinib response in patients with advanced non–small cell lung cancer (NSCLC) harboring focal MET amplifications: Analysis from the phase 2, multicohort GEOMETRY mono-1 study J Wolf, EB Garon, HJM Groen, DSW Tan, S Le Mouhaer, M Riester, L Ji, ... European Journal of Cancer 174, S21, 2022 | 1 | 2022 |
Clonal hematopoiesis detection in cancer patients using cell free DNA sequencing L Fairchild, J Whalen, K D’Aco, J Wu, CB Gustafson, N Solovieff, F Su, ... bioRxiv, 2021.10. 27.466159, 2021 | 1 | 2021 |
Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia G Minuesa Dinares, SK Albanese, A Chow, A Schurer, SM Park, ... Blood 132 (Supplement 1), 428-428, 2018 | 1 | 2018 |
Chromatin State Dynamics Underlying CD8 T Cell Differentiation and Dysfunction in Cancer M Philip, L Fairchild, L Sun, A Viale, T Merghoub, JD Wolchok, CS Leslie, ... Blood 128 (22), 861, 2016 | 1 | 2016 |
986P Response to capmatinib in patients (pts) with advanced non-small cell lung cancer (NSCLC) and MET exon 14 skipping (METex14) mutation: Whole transcriptome analysis from … J Wolf, HJM Groen, DSW Tan, EB Garon, D Demanse, A Robeva, ... Annals of Oncology 33, S1003, 2022 | | 2022 |