IL-12+ IL-18 cosignaling in human macrophages and lung epithelial cells activates cathelicidin and autophagy, inhibiting intracellular mycobacterial growth R Yang, E Yang, L Shen, RL Modlin, H Shen, ZW Chen The Journal of Immunology 200 (7), 2405-2417, 2018 | 70 | 2018 |
Synergistic efficacy of simultaneous anti-TGF-β/VEGF bispecific antibody and PD-1 blockade in cancer therapy M Niu, M Yi, Y Wu, L Lyu, Q He, R Yang, L Zeng, J Shi, J Zhang, P Zhou, ... Journal of hematology & oncology 16 (1), 94, 2023 | 45 | 2023 |
IL-12 expands and differentiates human Vγ2Vδ2 T effector cells producing antimicrobial cytokines and inhibiting intracellular mycobacterial growth R Yang, L Yao, L Shen, W Sha, RL Modlin, H Shen, ZW Chen Frontiers in immunology 10, 913, 2019 | 39 | 2019 |
Selective Destruction of Interleukin 23–Induced Expansion of a Major Antigen–Specific γδ T-Cell Subset in Patients With Tuberculosis H Shen, J Gu, H Xiao, S Liang, E Yang, R Yang, D Huang, C Chen, ... The Journal of Infectious Diseases 215 (3), 420-430, 2017 | 35 | 2017 |
Fast‐acting γδ T‐cell subpopulation and protective immunity against infections L Shen, D Huang, A Qaqish, J Frencher, R Yang, H Shen, ZW Chen Immunological Reviews 298 (1), 254-263, 2020 | 20 | 2020 |
Bispecific antibody PD-L1 x CD3 boosts the anti-tumor potency of the expanded Vγ2Vδ2 T cells R Yang, S Shen, C Gong, X Wang, F Luo, F Luo, Y Lei, Z Wang, S Xu, ... Frontiers in Immunology 12, 2021 | 17 | 2021 |
Multidrug-resistant tuberculosis (MDR-TB) strain infection in macaques results in high bacilli burdens in airways, driving broad innate/adaptive immune responses E Yang, R Yang, M Guo, D Huang, W Wang, Z Zhang, C Chen, F Wang, ... Emerging Microbes & Infections 7 (1), 1-12, 2018 | 17 | 2018 |
A CD4+ CD161+ T-cell subset present in unexposed humans, not Tb patients, are fast acting cells that inhibit the growth of intracellular mycobacteria involving CD161 pathway … R Yang, Y Peng, J Pi, Y Liu, E Yang, X Shen, L Yao, L Shen, RL Modlin, ... Frontiers in immunology 12, 599641, 2021 | 15 | 2021 |
Impairment of Wnt/β-catenin signaling in blood cells of patients with severe cavitary pulmonary tuberculosis L Fan, H Shen, H Huang, R Yang, L Yao PloS One 12 (3), e0172549, 2017 | 14 | 2017 |
Adjunctive Zoledronate+ IL-2 administrations enhance anti-tuberculosis Vγ2Vδ2 T-effector populations, and improve treatment outcome of multidrug-resistant tuberculosis1 H Shen, E Yang, M Guo, R Yang, G Huang, Y Peng, W Sha, F Wang, ... Emerging Microbes & Infections 11 (1), 1790-1805, 2022 | 13 | 2022 |
Vγ2 x PD-L1, a bispecific antibody targeting both the Vγ2 TCR and PD-L1, improves the anti-tumor response of Vγ2Vδ2 T cell R Yang, Q He, H Zhou, C Gong, X Wang, X Song, F Luo, Y Lei, Q Ni, ... Frontiers in Immunology 13, 923969, 2022 | 9 | 2022 |
Circular RNA circTRAPPC6B Enhances IL-6 and IL-1β Expression and Repolarizes Mycobacteria Induced Macrophages from M2- to M1-Like Phenotype by … Y Peng, XJ Wu, XJ Ji, GX Huang, T Wu, X Liu, R Yang, J Pi, HB Shen, ... Journal of Interferon & Cytokine Research 43 (6), 269-279, 2023 | 2 | 2023 |
The redirected killing of PD-L1 positive tumor cells by the expanded mucosa-associated invariant T (MAIT) cells is mediated with a bispecific antibody targeting TCR Vα7. 2 and … R Yang, Q He, J Zhang, Y Yan, J Shi, P Zhou Biochemical and Biophysical Research Communications 644, 1-7, 2023 | 1 | 2023 |