Mitogen-activated protein kinases p42mapk and p44mapk are required for fibroblast proliferation. G Pagès, P Lenormand, G L'Allemain, JC Chambard, S Meloche, ... Proceedings of the National Academy of Sciences 90 (18), 8319-8323, 1993 | 1296 | 1993 |
ERK implication in cell cycle regulation JC Chambard, R Lefloch, J Pouysségur, P Lenormand Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (8), 1299-1310, 2007 | 979 | 2007 |
Growth factors induce nuclear translocation of MAP kinases (p42mapk and p44mapk) but not of their activator MAP kinase kinase (p45mapkk) in fibroblasts P Lenormand, C Sardet, G L'Allemain, A Brunet, J Pouyssegur Journal of Cell Biology 122 (5), 1079-1088, 1993 | 862 | 1993 |
Nuclear translocation of p42/p44 mitogen‐activated protein kinase is required for growth factor‐induced gene expression and cell cycle entry A Brunet, DL Roux, P Lenormand, S Dowd, S Keyse, J Pouysségur The EMBO journal, 1999 | 768 | 1999 |
Fidelity and spatio-temporal control in MAP kinase (ERKs) signalling J Pouysségur, V Volmat, P Lenormand Biochemical pharmacology 64 (5-6), 755-763, 2002 | 571 | 2002 |
Growth factor–induced p42/p44 MAPK nuclear translocation and retention requires both MAPK activation and neosynthesis of nuclear anchoring proteins P Lenormand, JM Brondello, A Brunet, J Pouysségur Journal of Cell Biology 142 (3), 625-633, 1998 | 272 | 1998 |
Single and combined silencing of ERK1 and ERK2 reveals their positive contribution to growth signaling depending on their expression levels R Lefloch, J Pouysségur, P Lenormand Molecular and cellular biology 28 (1), 511-527, 2008 | 269 | 2008 |
Fidelity and spatio‐temporal control in MAP kinase (ERKs) signalling: Delivered on 24 October 2002 at the 28th FEBS Meeting in Istanbul J Pouysségur, P Lenormand European journal of biochemistry 270 (16), 3291-3299, 2003 | 233 | 2003 |
ERK1 and ERK2 map kinases: specific roles or functional redundancy? R Buscà, J Pouysségur, P Lenormand Frontiers in cell and developmental biology 4, 53, 2016 | 220 | 2016 |
TRB3 inhibits the transcriptional activation of stress-regulated genes by a negative feedback on the ATF4 pathway C Jousse, C Deval, AC Maurin, L Parry, Y Chérasse, C Chaveroux, ... Journal of Biological Chemistry 282 (21), 15851-15861, 2007 | 204 | 2007 |
The nucleus, a site for signal termination by sequestration and inactivation of p42/p44 MAP kinases V Volmat, M Camps, S Arkinstall, J Pouysségur, P Lenormand Journal of cell science 114 (19), 3433-3443, 2001 | 185 | 2001 |
ERK Nuclear Translocation Is Dimerization-independent but Controlled by the Rate of Phosphorylation*♦ DS Lidke, F Huang, JN Post, B Rieger, J Wilsbacher, JL Thomas, ... Journal of Biological Chemistry 285 (5), 3092-3102, 2010 | 147 | 2010 |
Total ERK1/2 activity regulates cell proliferation R Lefloch, J Pouysségur, P Lenormand Cell cycle 8 (5), 705-711, 2009 | 146 | 2009 |
Oncogenic Raf-1 activates p70 S6 kinase via a mitogen-activated protein kinase-independent pathway P Lenormand, M McMahon, J Pouysségur Journal of Biological Chemistry 271 (26), 15762-15768, 1996 | 111 | 1996 |
Inhibition of B56-containing protein phosphatase 2As by the early response gene IEX-1 leads to control of Akt activity C Letourneux, P Lenormand, F Porteu Journal of Biological Chemistry 282 (8), 5468-5477, 2007 | 109 | 2007 |
p42/p44 MAPKs are intracellular targets of the CDK inhibitor purvalanol M Knockaert, P Lenormand, N Gray, P Schultz, J Pouyssegur, L Meijer Oncogene 21 (42), 6413-6424, 2002 | 99 | 2002 |
MAP kinases: activation, subcellular localization and role in the control of cell proliferation. P Lenormand, C Sardet, G L'Allemain, S Meloche, J Pouysségur Advances in second messenger and phosphoprotein research 28, 237-244, 1993 | 69 | 1993 |
Endosulfan decreases cell growth and apoptosis in human HaCaT keratinocytes: Partial ROS‐dependent ERK1/2 mechanism S Antherieu, N Ledirac, AP Luzy, P Lenormand, JC Caron, R Rahmani Journal of cellular physiology 213 (1), 177-186, 2007 | 60 | 2007 |
Activation of ERK, controlled by Rac1 and Cdc42 via Akt, is required for anoikis W Rul, O Zugasti, P Roux, C Peyssonnaux, A Eychene, TF Franke, ... Annals of the New York Academy of Sciences 973 (1), 145-148, 2002 | 52 | 2002 |
Modulation of RNA expression by intracellular calcium. Existence of a threshold calcium concentration for induction of VL30 RNA by epidermal growth factor, endothelin, and … KD Rodland, LL Muldoon, P Lenormand, BE Magun Journal of Biological Chemistry 265 (19), 11000-11007, 1990 | 40 | 1990 |