Identification and characterization of tumorigenic liver cancer stem/progenitor cells S Ma, KW Chan, L Hu, TKW Lee, JYH Wo, IOL Ng, BJ Zheng, XY Guan Gastroenterology 132 (7), 2542-2556, 2007 | 1564 | 2007 |
CD133+ HCC cancer stem cells confer chemoresistance by preferential expression of the Akt/PKB survival pathway S Ma, TK Lee, BJ Zheng, KW Chan, XY Guan Oncogene 27 (12), 1749-1758, 2008 | 964 | 2008 |
CD24+ liver tumor-initiating cells drive self-renewal and tumor initiation through STAT3-mediated NANOG regulation TKW Lee, A Castilho, VCH Cheung, KH Tang, S Ma, IOL Ng Cell stem cell 9 (1), 50-63, 2011 | 691 | 2011 |
Aldehyde dehydrogenase discriminates the CD133 liver cancer stem cell populations S Ma, KW Chan, TKW Lee, KH Tang, JYH Wo, BJ Zheng, XY Guan Molecular Cancer Research 6 (7), 1146-1153, 2008 | 606 | 2008 |
Twist overexpression correlates with hepatocellular carcinoma metastasis through induction of epithelial-mesenchymal transition TK Lee, RTP Poon, AP Yuen, MT Ling, WK Kwok, XH Wang, YC Wong, ... Clinical cancer research 12 (18), 5369-5376, 2006 | 524 | 2006 |
miR-130b promotes CD133+ liver tumor-initiating cell growth and self-renewal via tumor protein 53-induced nuclear protein 1 S Ma, KH Tang, YP Chan, TK Lee, PS Kwan, A Castilho, I Ng, K Man, ... Cell stem cell 7 (6), 694-707, 2010 | 456 | 2010 |
Cancer stem cells in hepatocellular carcinoma—from origin to clinical implications TKW Lee, XY Guan, S Ma Nature reviews Gastroenterology & hepatology 19 (1), 26-44, 2022 | 334 | 2022 |
Cancer-associated fibroblasts regulate tumor-initiating cell plasticity in hepatocellular carcinoma through c-Met/FRA1/HEY1 signaling EYT Lau, J Lo, BYL Cheng, MKF Ma, JMF Lee, JKY Ng, S Chai, CH Lin, ... Cell reports 15 (6), 1175-1189, 2016 | 317 | 2016 |
CD133+ liver tumor‐initiating cells promote tumor angiogenesis, growth, and self‐renewal through neurotensin/interleukin‐8/CXCL1 signaling KH Tang, S Ma, TK Lee, YP Chan, PS Kwan, CM Tong, IO Ng, K Man, ... Hepatology 55 (3), 807-820, 2012 | 299 | 2012 |
Graft injury in relation to graft size in right lobe live donor liver transplantation: a study of hepatic sinusoidal injury in correlation with portal hemodynamics and … K Man, ST Fan, CM Lo, CL Liu, PCW Fung, TB Liang, TKW Lee, SHT Tsui, ... Annals of surgery 237 (2), 256-264, 2003 | 293 | 2003 |
Warburg metabolism in tumor-conditioned macrophages promotes metastasis in human pancreatic ductal adenocarcinoma HL Penny, JL Sieow, G Adriani, WH Yeap, P See Chi Ee, B San Luis, ... Oncoimmunology 5 (8), e1191731, 2016 | 251 | 2016 |
Blockade of CD47‐mediated cathepsin S/protease‐activated receptor 2 signaling provides a therapeutic target for hepatocellular carcinoma TKW Lee, VCH Cheung, P Lu, EYT Lau, S Ma, KH Tang, M Tong, J Lo, ... Hepatology 60 (1), 179-191, 2014 | 201 | 2014 |
Nuclear factor kappa B–mediated CD47 up‐regulation promotes sorafenib resistance and its blockade synergizes the effect of sorafenib in hepatocellular carcinoma in mice J Lo, EYT Lau, RHH Ching, BYL Cheng, MKF Ma, IOL Ng, TKW Lee Hepatology 62 (2), 534-545, 2015 | 200 | 2015 |
SENP1 promotes hypoxia-induced cancer stemness by HIF-1α deSUMOylation and SENP1/HIF-1α positive feedback loop CP Cui, CCL Wong, AKL Kai, DWH Ho, EYT Lau, YM Tsui, LK Chan, ... Gut 66 (12), 2149-2159, 2017 | 197 | 2017 |
Octamer 4/microRNA‐1246 signaling axis drives Wnt/β‐catenin activation in liver cancer stem cells S Chai, KY Ng, M Tong, EY Lau, TK Lee, KW Chan, YF Yuan, TT Cheung, ... Hepatology 64 (6), 2062-2076, 2016 | 193 | 2016 |
Doxorubicin-induced apoptosis and chemosensitivity in hepatoma cell lines T Lee, T Lau, I Ng Cancer chemotherapy and pharmacology 49, 78-86, 2002 | 177 | 2002 |
DLC-1 is deleted in primary hepatocellular carcinoma and exerts inhibitory effects on the proliferation of hepatoma cell lines with deleted DLC-1 IO Ng, Z Liang, L Cao, TK Lee Cancer research 60 (23), 6581-6584, 2000 | 175 | 2000 |
Circulating tumour cells as a biomarker for diagnosis and staging in pancreatic cancer JS Ankeny, CM Court, S Hou, Q Li, M Song, D Wu, JF Chen, T Lee, M Lin, ... British journal of cancer 114 (12), 1367-1375, 2016 | 170 | 2016 |
Ischemia‐reperfusion of small liver remnant promotes liver tumor growth and metastases—Activation of cell invasion and migration pathways K Man, KT Ng, CM Lo, JW Ho, BS Sun, CK Sun, TK Lee, RTP Poon, ... Liver transplantation 13 (12), 1669-1677, 2007 | 169 | 2007 |
Pin1 interacts with a specific serine-proline motif of hepatitis B virus X-protein to enhance hepatocarcinogenesis R Pang, TKW Lee, RTP Poon, ST Fan, KB Wong, YL Kwong, E Tse Gastroenterology 132 (3), 1088-1103, 2007 | 167 | 2007 |