| Dynamic landscape of immune cell-specific gene regulation in immune-mediated diseases M Ota, Y Nagafuchi, H Hatano, K Ishigaki, C Terao, Y Takeshima, ... Cell 184 (11), 3006-3021. e17, 2021 | 221 | 2021 |
| Distinct transcriptome architectures underlying lupus establishment and exacerbation M Nakano, M Ota, Y Takeshima, Y Iwasaki, H Hatano, Y Nagafuchi, ... Cell 185 (18), 3375-3389. e21, 2022 | 69 | 2022 |
| TGF-β3 inhibits antibody production by human B cells Y Tsuchida, S Sumitomo, K Ishigaki, A Suzuki, Y Kochi, H Tsuchiya, M Ota, ... PLoS One 12 (1), e0169646, 2017 | 51 | 2017 |
| Parsing multiomics landscape of activated synovial fibroblasts highlights drug targets linked to genetic risk of rheumatoid arthritis H Tsuchiya, M Ota, S Sumitomo, K Ishigaki, A Suzuki, T Sakata, ... Annals of the rheumatic diseases 80 (4), 440-450, 2021 | 49 | 2021 |
| CRISPR screens decode cancer cell pathways that trigger γδ T cell detection MR Mamedov, S Vedova, JW Freimer, AD Sahu, A Ramesh, MM Arce, ... Nature 621 (7977), 188-195, 2023 | 47 | 2023 |
| Efficacy of intensive immunosuppression in exacerbated rheumatoid arthritis-associated interstitial lung disease M Ota, Y Iwasaki, H Harada, O Sasaki, Y Nagafuchi, S Nakachi, ... Modern Rheumatology 27 (1), 22-28, 2017 | 44 | 2017 |
| Immune cell multiomics analysis reveals contribution of oxidative phosphorylation to B-cell functions and organ damage of lupus Y Takeshima, Y Iwasaki, M Nakano, Y Narushima, M Ota, Y Nagafuchi, ... Annals of the rheumatic diseases 81 (6), 845-853, 2022 | 38 | 2022 |
| Transcriptome analysis of peripheral blood from patients with rheumatoid arthritis: a systematic review S Sumitomo, Y Nagafuchi, Y Tsuchida, H Tsuchiya, M Ota, K Ishigaki, ... Inflammation and Regeneration 38, 1-5, 2018 | 36 | 2018 |
| Base-editing mutagenesis maps alleles to tune human T cell functions R Schmidt, CC Ward, R Dajani, Z Armour-Garb, M Ota, V Allain, ... Nature 625 (7996), 805-812, 2024 | 33 | 2024 |
| Multi-omics approach to precision medicine for immune-mediated diseases M Ota, K Fujio Inflammation and regeneration 41 (1), 23, 2021 | 32 | 2021 |
| Integrated bulk and single-cell RNA-sequencing identified disease-relevant monocytes and a gene network module underlying systemic sclerosis S Kobayashi, Y Nagafuchi, M Okubo, Y Sugimori, H Shirai, H Hatano, ... Journal of Autoimmunity 116, 102547, 2021 | 30 | 2021 |
| Immunomics analysis of rheumatoid arthritis identified precursor dendritic cells as a key cell subset of treatment resistance S Yamada, Y Nagafuchi, M Wang, M Ota, H Hatano, Y Takeshima, ... Annals of the rheumatic diseases 82 (6), 809-819, 2023 | 28 | 2023 |
| A gene module associated with dysregulated TCR signaling pathways in CD4+ T cell subsets in rheumatoid arthritis S Sumitomo, Y Nagafuchi, Y Tsuchida, H Tsuchiya, M Ota, K Ishigaki, ... Journal of autoimmunity 89, 21-29, 2018 | 27 | 2018 |
| Multiomics landscape of synovial fibroblasts in rheumatoid arthritis H Tsuchiya, M Ota, K Fujio Inflammation and regeneration 41, 1-6, 2021 | 23 | 2021 |
| Serum extracellular traps associate with the activation of myeloid cells in SLE patients with the low level of anti-DNA antibodies N Hanata, M Ota, Y Tsuchida, Y Nagafuchi, T Okamura, H Shoda, K Fujio Scientific Reports 12 (1), 18397, 2022 | 19 | 2022 |
| A dose-escalation regimen of trimethoprim–sulfamethoxazole is tolerable for prophylaxis against Pneumocystis jiroveci pneumonia in rheumatic diseases K Takenaka, Y Komiya, M Ota, H Yamazaki, K Nagasaka Modern rheumatology 23 (4), 752-758, 2013 | 19 | 2013 |
| Multimodal repertoire analysis unveils B cell biology in immune-mediated diseases M Ota, M Nakano, Y Nagafuchi, S Kobayashi, H Hatano, R Yoshida, ... Annals of the rheumatic diseases 82 (11), 1455-1463, 2023 | 18 | 2023 |
| Transcriptome analysis of immune cells from Behçet’s syndrome patients: the importance of IL-17-producing cells and antigen-presenting cells in the pathogenesis of Behçet’s … M Okubo, S Sumitomo, Y Tsuchida, Y Nagafuchi, Y Takeshima, ... Arthritis research & therapy 24 (1), 186, 2022 | 15 | 2022 |
| AFF3, a susceptibility factor for autoimmune diseases, is a molecular facilitator of immunoglobulin class switch recombination S Tsukumo, PG Subramani, N Seija, M Tabata, Y Maekawa, Y Mori, ... Science Advances 8 (34), eabq0008, 2022 | 14 | 2022 |
| Age-associated CD4+ T cells with B cell–promoting functions are regulated by ZEB2 in autoimmunity M Goto, H Takahashi, R Yoshida, T Itamiya, M Nakano, Y Nagafuchi, ... Science Immunology 9 (93), eadk1643, 2024 | 11 | 2024 |
