Ancient migratory events in the Middle East: new clues from the Y-chromosome variation of modern Iranians V Grugni, V Battaglia, B Hooshiar Kashani, S Parolo, N Al-Zahery, ... PloS one 7 (7), e41252, 2012 | 144 | 2012 |
A computationally driven analysis of the polyphenol-protein interactome S Lacroix, J Klicic Badoux, MP Scott-Boyer, S Parolo, A Matone, C Priami, ... Scientific reports 8 (1), 2232, 2018 | 89 | 2018 |
History and future perspectives on the discipline of quantitative systems pharmacology modeling and its applications K Azer, CD Kaddi, JS Barrett, JPF Bai, ST McQuade, NJ Merrill, B Piccoli, ... Frontiers in physiology 12, 637999, 2021 | 81 | 2021 |
Population structure of modern-day Italians reveals patterns of ancient and archaic ancestries in Southern Europe A Raveane, S Aneli, F Montinaro, G Athanasiadis, S Barlera, G Birolo, ... Science Advances 5 (9), eaaw3492, 2019 | 68 | 2019 |
A network-based approach to identify deregulated pathways and drug effects in metabolic syndrome K Misselbeck, S Parolo, F Lorenzini, V Savoca, L Leonardelli, P Bora, ... Nature communications 10 (1), 5215, 2019 | 66 | 2019 |
A QSP model of prostate cancer immunotherapy to identify effective combination therapies R Coletti, L Leonardelli, S Parolo, L Marchetti Scientific reports 10 (1), 9063, 2020 | 37 | 2020 |
Are myocardial infarction–associated single-nucleotide polymorphisms associated with ischemic stroke? YC Cheng, CD Anderson, S Bione, K Keene, JM Maguire, M Nalls, ... Stroke 43 (4), 980-986, 2012 | 37 | 2012 |
Combined use of protein biomarkers and network analysis unveils deregulated regulatory circuits in Duchenne muscular dystrophy S Parolo, L Marchetti, M Lauria, K Misselbeck, MP Scott-Boyer, ... PLoS One 13 (3), e0194225, 2018 | 32 | 2018 |
Integration of transcriptomic and genomic data suggests candidate mechanisms for APOE4-mediated pathogenic action in Alzheimer’s disease L Caberlotto, L Marchetti, M Lauria, M Scotti, S Parolo Scientific Reports 6 (1), 32583, 2016 | 30 | 2016 |
Lysosomal cystine export regulates mTORC1 signaling to guide kidney epithelial cell fate specialization M Berquez, Z Chen, BP Festa, P Krohn, SA Keller, S Parolo, M Korzinkin, ... Nature communications 14 (1), 3994, 2023 | 27 | 2023 |
Heritability of young‐and old‐onset ischaemic stroke A Bluher, WJ Devan, EG Holliday, M Nalls, S Parolo, S Bione, AK Giese, ... European journal of neurology 22 (11), 1488-1491, 2015 | 27 | 2015 |
A reverse metabolic approach to weaning: in silico identification of immune-beneficial infant gut bacteria, mining their metabolism for prebiotic feeds and sourcing these feeds … S Michelini, B Balakrishnan, S Parolo, A Matone, JA Mullaney, W Young, ... Microbiome 6, 1-18, 2018 | 26 | 2018 |
Single-cell-led drug repurposing for Alzheimer’s disease S Parolo, F Mariotti, P Bora, L Carboni, E Domenici Scientific Reports 13 (1), 222, 2023 | 14 | 2023 |
Characterization of the biological processes shaping the genetic structure of the Italian population S Parolo, A Lisa, D Gentilini, AM Di Blasio, S Barlera, EB Nicolis, ... BMC genetics 16, 1-11, 2015 | 14 | 2015 |
An association rule mining approach to discover lncRNAs expression patterns in cancer datasets P Cremaschi, R Carriero, S Astrologo, C Colì, A Lisa, S Parolo, S Bione BioMed research international 2015 (1), 146250, 2015 | 10 | 2015 |
Ancestors’ dietary patterns and environments could drive positive selection in genes involved in micronutrient metabolism—the case of cofactor transporters S Parolo, S Lacroix, J Kaput, MP Scott-Boyer Genes & Nutrition 12, 1-10, 2017 | 9 | 2017 |
Computational analysis of cytokine release following bispecific T-cell engager therapy: applications of a logic-based model G Selvaggio, S Parolo, P Bora, L Leonardelli, J Harrold, K Mehta, ... Frontiers in Oncology 12, 818641, 2022 | 8 | 2022 |
Literature mining and mechanistic graphical modelling to improve mRNA vaccine platforms L Leonardelli, G Lofano, G Selvaggio, S Parolo, S Giampiccolo, ... Frontiers in immunology 12, 738388, 2021 | 8 | 2021 |
Integrated quantitative systems pharmacology (QSP) model of lysosomal diseases provides an innovative computational platform to support research and therapeutic development for … C Kaddi, F Reali, L Marchetti, B Niesner, S Parolo, G Simoni, S Zaph, ... Molecular Genetics and Metabolism 123 (2), S73-S74, 2018 | 8 | 2018 |
A pediatric quantitative systems pharmacology model of neurofilament trafficking in spinal muscular atrophy treated with the antisense oligonucleotide nusinersen A Paris, P Bora, S Parolo, D MacCannell, M Monine, N van der Munnik, ... CPT: Pharmacometrics & Systems Pharmacology 12 (2), 196-206, 2023 | 7 | 2023 |