| Polyglutamine diseases: the special case of ataxin-3 and Machado–Joseph disease CA Matos, S de Macedo-Ribeiro, AL Carvalho Progress in neurobiology 95 (1), 26-48, 2011 | 177 | 2011 |
| Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation? A Marcelo, R Koppenol, LP de Almeida, CA Matos, C Nóbrega Cell death & disease 12 (6), 592, 2021 | 148 | 2021 |
| Machado–Joseph disease/spinocerebellar ataxia type 3: lessons from disease pathogenesis and clues into therapy CA Matos, LP de Almeida, C Nóbrega Journal of neurochemistry 148 (1), 8-28, 2019 | 135 | 2019 |
| MSGP: the first database of the protein components of the mammalian stress granules C Nunes, I Mestre, A Marcelo, R Koppenol, CA Matos, C Nóbrega Database 2019, baz031, 2019 | 74 | 2019 |
| Restoring brain cholesterol turnover improves autophagy and has therapeutic potential in mouse models of spinocerebellar ataxia C Nóbrega, L Mendonça, A Marcelo, A Lamazière, S Tomé, G Despres, ... Acta Neuropathologica 138, 837-858, 2019 | 70 | 2019 |
| Cordycepin activates autophagy through AMPK phosphorylation to reduce abnormalities in Machado–Joseph disease models A Marcelo, F Brito, S Carmo-Silva, CA Matos, J Alves-Cruzeiro, ... Human Molecular Genetics 28 (1), 51-63, 2019 | 50 | 2019 |
| Ataxin-3 phosphorylation decreases neuronal defects in spinocerebellar ataxia type 3 models CA Matos, C Nóbrega, SR Louros, B Almeida, E Ferreiro, J Valero, ... Journal of Cell Biology 212 (4), 465-480, 2016 | 50 | 2016 |
| Assessing cognitive decline in the aging brain: Lessons from rodent and human studies DVC Brito, F Esteves, AT Rajado, N Silva, I Araújo, J Bragança, ... npj Aging 9 (1), 23, 2023 | 48 | 2023 |
| SUMOylation of the brain-predominant Ataxin-3 isoform modulates its interaction with p97 B Almeida, IA Abreu, CA Matos, JS Fraga, S Fernandes, MG Macedo, ... Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease 1852 (9 …, 2015 | 46 | 2015 |
| Proteolytic cleavage of polyglutamine disease-causing proteins: revisiting the toxic fragment hypothesis C A Matos, L Pereira de Almeida, C Nobrega Current Pharmaceutical Design 23 (5), 753-775, 2017 | 44 | 2017 |
| A Handbook of Gene and Cell Therapy C Nóbrega, L Mendonça, CA Matos | 33 | 2020 |
| Autophagy in Spinocerebellar ataxia type 2, a dysregulated pathway, and a target for therapy A Marcelo, IT Afonso, R Afonso-Reis, DVC Brito, RG Costa, A Rosa, ... Cell Death & Disease 12 (12), 1117, 2021 | 28 | 2021 |
| Gene therapies for polyglutamine diseases CA Matos, V Carmona, UG Vijayakumar, S Lopes, P Albuquerque, ... Polyglutamine Disorders, 395-438, 2018 | 28 | 2018 |
| Ibuprofen enhances synaptic function and neural progenitors proliferation markers and improves neuropathology and motor coordination in Machado–Joseph disease models LS Mendonça, C Nóbrega, S Tavino, M Brinkhaus, C Matos, S Tomé, ... Human Molecular Genetics 28 (22), 3691-3703, 2019 | 26 | 2019 |
| The cholesterol 24-hydroxylase activates autophagy and decreases mutant huntingtin build-up in a neuroblastoma culture model of Huntington’s disease C Nóbrega, A Conceição, RG Costa, R Koppenol, RL Sequeira, R Nunes, ... BMC Research Notes 13, 1-9, 2020 | 20 | 2020 |
| How can we modulate aging through nutrition and physical exercise? An epigenetic approach AT Rajado, N Silva, F Esteves, D Brito, A Binnie, IM Araújo, C Nóbrega, ... Aging (Albany NY) 15 (8), 3191, 2023 | 17 | 2023 |
| The stress granule protein G3BP1 alleviates spinocerebellar ataxia-associated deficits R Koppenol, A Conceição, IT Afonso, R Afonso-Reis, RG Costa, S Tomé, ... Brain 146 (6), 2346-2363, 2023 | 16 | 2023 |
| Reprogramming iPSCs to study age-related diseases: models, therapeutics, and clinical trials F Esteves, D Brito, AT Rajado, N Silva, J Apolónio, VP Roberto, I Araújo, ... Mechanisms of Ageing and Development 214, 111854, 2023 | 9 | 2023 |
| The polyglutamine protein ATXN2: from its molecular functions to its involvement in disease RG Costa, A Conceição, CA Matos, C Nóbrega Cell Death & Disease 15 (6), 415, 2024 | 7 | 2024 |
| Mutant ataxin-2 expression in aged animals aggravates neuropathological features associated with spinocerebellar ataxia type 2 IT Afonso, P Lima, A Conceição, CA Matos, C Nóbrega International journal of molecular sciences 23 (19), 11896, 2022 | 6 | 2022 |
