| Oral mucosal organoids as a potential platform for personalized cancer therapy E Driehuis, S Kolders, S Spelier, K Lõhmussaar, SM Willems, LA Devriese, ... Cancer discovery 9 (7), 852-871, 2019 | 338 | 2019 |
| Dietary lipids fuel GPX4-restricted enteritis resembling Crohn’s disease L Mayr, F Grabherr, J Schwärzler, I Reitmeier, F Sommer, T Gehmacher, ... Nature Communications 11 (1), 1775, 2020 | 205 | 2020 |
| The pseudokinase MLKL mediates programmed hepatocellular necrosis independently of RIPK3 during hepatitis C Günther, GW He, AE Kremer, JM Murphy, EJ Petrie, K Amann, ... The Journal of clinical investigation 126 (11), 4346-4360, 2016 | 166 | 2016 |
| Programming of intestinal epithelial differentiation by IL-33 derived from pericryptal fibroblasts in response to systemic infection M Mahapatro, S Foersch, M Hefele, GW He, E Giner-Ventura, ... Cell Reports 15 (8), 1743-1756, 2016 | 128 | 2016 |
| Caspase-8 controls the gut response to microbial challenges by Tnf-α-dependent and independent pathways C Günther, B Buchen, GW He, M Hornef, N Torow, H Neumann, ... Gut 64 (4), 601-610, 2015 | 119 | 2015 |
| Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways GR Yan, CL Xiao, GW He, XF Yin, NP Chen, Y Cao, QY He Proteomics 10 (5), 976-986, 2010 | 118 | 2010 |
| PGAM5-mediated programmed necrosis of hepatocytes drives acute liver injury GW He, C Günther, AE Kremer, V Thonn, K Amann, C Poremba, ... Gut 66 (4), 716-723, 2017 | 105 | 2017 |
| Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation GW He, L Lin, J DeMartino, X Zheng, N Staliarova, T Dayton, H Begthel, ... Cell Stem Cell 29 (9), 1333-1345. e6, 2022 | 102 | 2022 |
| Interferon lambda promotes paneth cell death via STAT1 signaling in mice and is increased in inflamed ileal tissues of patients with Crohn’s disease C Günther, B Ruder, I Stolzer, H Dorner, GW He, MT Chiriac, K Aden, ... Gastroenterology 157 (5), 1310-1322. e13, 2019 | 85 | 2019 |
| Cellular FLICE-like inhibitory protein secures intestinal epithelial cell survival and immune homeostasis by regulating caspase-8 N Wittkopf, C Günther, E Martini, G He, K Amann, YW He, M Schuchmann, ... Gastroenterology 145 (6), 1369-1379, 2013 | 81 | 2013 |
| Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice GW He, C Günther, V Thonn, YQ Yu, E Martini, B Buchen, MF Neurath, ... Journal of Experimental Medicine 214 (6), 1655-1662, 2017 | 75 | 2017 |
| Intestinal epithelial Caspase-8 signaling is essential to prevent necroptosis during Salmonella Typhimurium induced enteritis M Hefele, I Stolzer, B Ruder, GW He, M Mahapatro, S Wirtz, MF Neurath, ... Mucosal Immunology 11 (4), 1191-1202, 2018 | 59 | 2018 |
| Wheat consumption aggravates colitis in mice via amylase trypsin inhibitor–mediated dysbiosis G Pickert, S Wirtz, J Matzner, M Ashfaq-Khan, R Heck, S Rosigkeit, ... Gastroenterology 159 (1), 257-272. e17, 2020 | 52 | 2020 |
| PGAM5 is a key driver of mitochondrial dysfunction in experimental lung fibrosis I Ganzleben, GW He, C Günther, ES Prigge, K Richter, RJ Rieker, ... Cellular and molecular life sciences 76, 4783-4794, 2019 | 34 | 2019 |
| Dynamic quantitative proteomics characterization of TNF-α-induced necroptosis Y Wang, ZH Huang, YJ Li, GW He, RY Yu, J Yang, WT Liu, B Li, QY He Apoptosis 21, 1438-1446, 2016 | 11 | 2016 |
| Epidermal growth factor receptor (EGFR) is a target of the tumor-suppressor E3 ligase FBXW7 M Boretto, MH Geurts, S Gandhi, Z Ma, N Staliarova, M Celotti, S Lim, ... Proceedings of the National Academy of Sciences 121 (12), e2309902121, 2024 | 7 | 2024 |
| Oral mucosal organoids as a potential platform for personalized cancer therapy. Cancer Discov 9 (7): 852–871 E Driehuis, S Kolders, S Spelier, K Lõhmussaar, SM Willems, LA Devriese, ... | 5 | 2019 |
| Signaling networks in gastric cancer cells revealed by phosphoproteomics GR Yan, NP Chen, YD Huang, W Ding, GW He, CL Xiao, XF Yin, QY He JPB 3 (4), 2010 | 5 | 2010 |
| Programming of intestinal epithelial differentiation by IL-33 derived from pericryptal fibroblasts in response to systemic infection. Cell Rep 15: 1743–1756 M Mahapatro, S Foersch, M Hefele, GW He, E Giner-Ventura, ... | 3 | 2016 |
| Suggested searches E Axell, J Hu, M Lindberg, AJ Dear, L Ortigosa-Pascual, EA Andrzejewska, ... Perspective, 2024 | | 2024 |
Christoph BeckerProfessor for Molecular Gastroenterology, Department of Medicine 1, University of Erlangen-NürnbergE-mailová adresa ověřena na: uk-erlangen.de
