| Integrin signaling in cancer: mechanotransduction, stemness, epithelial plasticity, and therapeutic resistance J Cooper, FG Giancotti Cancer cell 35 (3), 347-367, 2019 | 770 | 2019 |
| Merlin/NF2 Suppresses Tumorigenesis by Inhibiting the E3 Ubiquitin Ligase CRL4-DCAF1 in the Nucleus W Li, L You, J Cooper, G Schiavon, A Pepe-Caprio, L Zhou, R Ishii, ... Cell 140 (4), 477-490, 2010 | 386 | 2010 |
| Merlin/NF2 Loss-Driven Tumorigenesis Linked to CRL4DCAF1-Mediated Inhibition of the Hippo Pathway Kinases Lats1 and 2 in the Nucleus W Li, J Cooper, L Zhou, C Yang, H Erdjument-Bromage, D Zagzag, ... Cancer cell 26 (1), 48-60, 2014 | 263 | 2014 |
| Molecular insights into NF2/Merlin tumor suppressor function J Cooper, FG Giancotti FEBS letters 588 (16), 2743-2752, 2014 | 224 | 2014 |
| Merlin: a tumour suppressor with functions at the cell cortex and in the nucleus W Li, J Cooper, MA Karajannis, FG Giancotti EMBO reports 13 (3), 204-215, 2012 | 153 | 2012 |
| A stromal niche defined by expression of the transcription factor WT1 mediates programming and homeostasis of cavity-resident macrophages MB Buechler, KW Kim, EJ Onufer, JW Williams, CC Little, CX Dominguez, ... Immunity 51 (1), 119-130. e5, 2019 | 130 | 2019 |
| Kras mutant genetically engineered mouse models of human cancers are genomically heterogeneous WJ Chung, A Daemen, JH Cheng, JE Long, JE Cooper, B Wang, C Tran, ... Proceedings of the National Academy of Sciences 114 (51), E10947-E10955, 2017 | 79 | 2017 |
| Merlin/NF2 functions upstream of the nuclear E3 ubiquitin ligase CRL4DCAF1 to suppress oncogenic gene expression J Cooper, W Li, L You, G Schiavon, A Pepe-Caprio, L Zhou, R Ishii, ... Science Signaling 4 (188), pt6, 2011 | 58 | 2011 |
| Combined Inhibition of NEDD8-Activating Enzyme and mTOR Suppresses NF2 Loss–Driven Tumorigenesis J Cooper, Q Xu, L Zhou, M Pavlovic, V Ojeda, K Moulick, E De Stanchina, ... Molecular cancer therapeutics 16 (8), 1693-1704, 2017 | 45 | 2017 |
| Transcriptional subtypes resolve tumor heterogeneity and identify vulnerabilities to MEK inhibition in lung adenocarcinoma A Daemen, JE Cooper, S Myrta, MJ Wongchenko, E Lin, JE Long, ... Clinical Cancer Research 27 (4), 1162-1173, 2021 | 17 | 2021 |
| A mesothelioma in a ferruginous hawk (Buteo regalis) JE Cooper, SL Pugsley Avian Pathology 13 (4), 797-801, 1984 | 10 | 1984 |
| Cancer: a new role for non-canonical Hippo signaling J Cooper, FG Giancotti Cell Research 27 (4), 459-460, 2017 | 5 | 2017 |
| Correction: combined inhibition of NEDD8-activating enzyme and mTOR suppresses NF2 loss-driven tumorigenesis J Cooper, Q Xu, L Zhou, M Pavlovic, V Ojeda, K Moulick, E de Stanchina, ... Molecular cancer therapeutics 20 (2), 450, 2021 | 1 | 2021 |
| Abstract PO-101: Transcriptional heterogeneity in lung adenocarcinoma reveals distinct therapeutic vulnerabilities A Daemen, JE Cooper, S Myrta, MJ Wongchenko, E Lin, JE Long, ... Cancer Research 80 (21_Supplement), PO-101-PO-101, 2020 | | 2020 |
| Abstract PO-099: SOX2 delineates a mouse lung adenocarcinoma subtype vulnerable to targeted therapy JE Cooper, A Daemen, D Nickles, S Myrta, O Foreman, J Eastham, ... Cancer Research 80 (21_Supplement), PO-099-PO-099, 2020 | | 2020 |
| A09 Transcriptional Subtypes Resolve Tumor Heterogeneity and Identify Therapeutic Vulnerabilities in Lung Cancer A Daemen, JE Cooper, S Myrta, M Wongchenko, E Lin, JE Long, ... Journal of Thoracic Oncology 15 (2), S14-S15, 2020 | | 2020 |
| Merlin/NF2-mediated tumor suppression: From mechanism to translation JE Cooper Weill Medical College of Cornell University, 2016 | | 2016 |
| A flexible mouse model of malignant pleural mesothelioma J Cooper, F Giancotti Cancer Research 75 (15_Supplement), 2896-2896, 2015 | | 2015 |
| GDC-0980, a dual PI3K/mTOR inhibitor, selectively inhibits NF2 mutant malignant mesothelioma (MM) cells and inhibits TOR signaling without activating Akt or ERK MG Zauderer, K Moulik, J Cooper, LM Krug, F Giancotti MOLECULAR CANCER THERAPEUTICS 14 (7), 2015 | | 2015 |
Filippo GiancottiColumbia University Comprehensive Cancer CenterE-mailová adresa ověřena na: cumc.columbia.edu
