| Cellular and synaptic adaptations mediating opioid dependence JT Williams, MDJ Christie, O Manzoni Physiological reviews 81 (1), 299-343, 2001 | 1167 | 2001 |
| Ultrafast neuronal imaging of dopamine dynamics with designed genetically encoded sensors T Patriarchi, JR Cho, K Merten, MW Howe, A Marley, WH Xiong, RW Folk, ... Science 360 (6396), eaat4422, 2018 | 1014 | 2018 |
| Regulation of µ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance JT Williams, SL Ingram, G Henderson, C Chavkin, M von Zastrow, ... Pharmacological reviews 65 (1), 223-254, 2013 | 926 | 2013 |
| Nicotine activates and desensitizes midbrain dopamine neurons VI Pidoplichko, M DeBiasi, JT Williams, JA Dani Nature 390 (6658), 401-404, 1997 | 917 | 1997 |
| Mu and delta receptors belong to a family of receptors that are coupled to potassium channels. RA North, JT Williams, A Surprenant, MJ Christie Proceedings of the National Academy of Sciences 84 (15), 5487-5491, 1987 | 832 | 1987 |
| Molecular cloning and tissue distribution of a putative member of the rat opioid receptor gene family that is not a μ, δ or κ opioid receptor type JR Bunzow, C Saez, M Mortrud, C Bouvier, JT Williams, M Low, ... FEBS letters 347 (2-3), 284-288, 1994 | 751 | 1994 |
| Afferent regulation of locus coeruleus neurons: anatomy, physiology and pharmacology G Aston-Jones, MT Shipley, G Chouvet, M Ennis, E Van Bockstaele, ... Progress in brain research 88, 47-75, 1991 | 685 | 1991 |
| Functional coupling between neurons and glia V Alvarez-Maubecin, F García-Hernández, JT Williams, ... Journal of Neuroscience 20 (11), 4091-4098, 2000 | 441 | 2000 |
| Vesicular dopamine release elicits an inhibitory postsynaptic current in midbrain dopamine neurons MJ Beckstead, DK Grandy, K Wickman, JT Williams Neuron 42 (6), 939-946, 2004 | 410 | 2004 |
| Membrane properties of rat locus coeruleus neurones JT Williams, RA North, SA Shefner, S Nishi, TM Egan Neuroscience 13 (1), 137-156, 1984 | 395 | 1984 |
| Properties and opioid inhibition of mesolimbic dopamine neurons vary according to target location CP Ford, GP Mark, JT Williams Journal of Neuroscience 26 (10), 2788-2797, 2006 | 382 | 2006 |
| Cellular mechanisms of opioid tolerance: studies in single brain neurons. MJ Christie, JT Williams, RA North Molecular pharmacology 32 (5), 633-638, 1987 | 375 | 1987 |
| Increased probability of GABA release during withdrawal from morphine A Bonci, JT Williams Journal of Neuroscience 17 (2), 796-803, 1997 | 365 | 1997 |
| Glutamate mediates an inhibitory postsynaptic potential in dopamine neurons CD Fiorillo, JT Williams Nature 394 (6688), 78-82, 1998 | 344 | 1998 |
| Dopamine D1 receptors facilitate transmitter release DL Cameron, JT Williams Nature 366 (6453), 344-347, 1993 | 342 | 1993 |
| Enkephalin opens potassium channels on mammalian central neurones JT Williams, TM Egan, RA North Nature 299 (5878), 74-77, 1982 | 333 | 1982 |
| On the potassium conductance increased by opioids in rat locus coeruleus neurones. RA North, JT Williams The Journal of physiology 364 (1), 265-280, 1985 | 326 | 1985 |
| Phosphorylation-deficient G-protein-biased μ-opioid receptors improve analgesia and diminish tolerance but worsen opioid side effects. A Kliewer, F Schmiedel, S Sianati, A Bailey, JT Bateman, ES Levitt, ... Nature Communication 10 (1), 367, 2019 | 306 | 2019 |
| Characterization of α2-adrenoceptors which increase potassium conductance in rat locus coeruleus neurones JT Williams, G Henderson, RA North Neuroscience 14 (1), 95-101, 1985 | 306 | 1985 |
| Voltage-and ligand-activated inwardly rectifying currents in dorsal raphe neurons in vitro JT Williams, WF Colmers, ZZ Pan Journal of Neuroscience 8 (9), 3499-3506, 1988 | 298 | 1988 |
