| KRAS-IRF2 axis drives immune suppression and immune therapy resistance in colorectal cancer W Liao, MJ Overman, AT Boutin, X Shang, D Zhao, P Dey, J Li, G Wang, ... Cancer cell 35 (4), 559-572. e7, 2019 | 529 | 2019 |
| Genetic and biological hallmarks of colorectal cancer J Li, X Ma, D Chakravarti, S Shalapour, RA DePinho Genes & development 35 (11-12), 787-820, 2021 | 404 | 2021 |
| Symbiotic macrophage-glioma cell interactions reveal synthetic lethality in PTEN-null glioma P Chen, D Zhao, J Li, X Liang, J Li, A Chang, VK Henry, Z Lan, DJ Spring, ... Cancer cell 35 (6), 868-884. e6, 2019 | 279 | 2019 |
| Widespread mitotic bookmarking by histone marks and transcription factors in pluripotent stem cells Y Liu, B Pelham-Webb, DC Di Giammartino, J Li, D Kim, K Kita, N Saiz, ... Cell reports 19 (7), 1283-1293, 2017 | 142 | 2017 |
| Tumor microenvironment remodeling enables bypass of oncogenic KRAS dependency in pancreatic cancer P Hou, A Kapoor, Q Zhang, J Li, CJ Wu, J Li, Z Lan, M Tang, X Ma, ... Cancer discovery 10 (7), 1058-1077, 2020 | 118 | 2020 |
| H3K27ac bookmarking promotes rapid post-mitotic activation of the pluripotent stem cell program without impacting 3D chromatin reorganization B Pelham-Webb, A Polyzos, L Wojenski, A Kloetgen, J Li, ... Molecular cell 81 (8), 1732-1748. e8, 2021 | 79 | 2021 |
| Chromatin regulator CHD1 remodels the immunosuppressive tumor microenvironment in PTEN-deficient prostate cancer D Zhao, L Cai, X Lu, X Liang, J Li, P Chen, M Ittmann, X Shang, S Jiang, ... Cancer discovery 10 (9), 1374-1387, 2020 | 79 | 2020 |
| Histone demethylase KDM5D upregulation drives sex differences in colon cancer J Li, Z Lan, W Liao, JW Horner, X Xu, J Liu, Y Yoshihama, S Jiang, ... Nature 619 (7970), 632-639, 2023 | 74 | 2023 |
| Telomere dysfunction activates YAP1 to drive tissue inflammation D Chakravarti, B Hu, X Mao, A Rashid, J Li, J Li, W Liao, EM Whitley, ... Nature communications 11 (1), 4766, 2020 | 70 | 2020 |
| Tumor cell-derived SPON2 promotes M2-polarized tumor-associated macrophage infiltration and cancer progression by activating PYK2 in CRC C Huang, R Ou, X Chen, Y Zhang, J Li, Y Liang, X Zhu, L Liu, M Li, D Lin, ... Journal of Experimental & Clinical Cancer Research 40, 1-17, 2021 | 62 | 2021 |
| Telomerase reverse transcriptase preserves neuron survival and cognition in Alzheimer’s disease models HS Shim, JW Horner, CJ Wu, J Li, ZD Lan, S Jiang, X Xu, WH Hsu, T Zal, ... Nature Aging 1 (12), 1162-1174, 2021 | 47 | 2021 |
| Synthetic Essentiality of Tryptophan 2,3-Dioxygenase 2 in APC-Mutated Colorectal Cancer R Lee, J Li, J Li, CJ Wu, S Jiang, WH Hsu, D Chakravarti, P Chen, ... Cancer discovery 12 (7), 1702-1717, 2022 | 40 | 2022 |
| A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus BE Aronson, L Scourzic, V Shah, E Swanzey, A Kloetgen, A Polyzos, ... Developmental cell 56 (22), 3052-3065. e5, 2021 | 20 | 2021 |
| TERT activation targets DNA methylation and multiple aging hallmarks HS Shim, J Iaconelli, X Shang, J Li, ZD Lan, S Jiang, K Nutsch, BA Beyer, ... Cell 187 (15), 4030-4042. e13, 2024 | 19 | 2024 |
| AR-negative prostate cancer is vulnerable to loss of JMJD1C demethylase Y Yoshihama, KA LaBella, E Kim, L Bertolet, M Colic, J Li, X Shang, ... Proceedings of the National Academy of Sciences 118 (36), e2026324118, 2021 | 10 | 2021 |
| Oncogenic KRAS drives immunosuppression of colorectal cancer by impairing DDX60-mediated dsRNA accumulation and viral mimicry Y Zhou, Y Zhang, M Li, T Ming, C Zhang, C Huang, J Li, F Li, H Li, E Zhao, ... Science Immunology 9 (100), eado8758, 2024 | 2 | 2024 |
| Mitotic retention of H3K27 acetylation promotes rapid topological and transcriptional resetting of stem cell-related genes and enhancers upon G1 entry B Pelham-Webb, A Polyzos, L Wojenski, A Kloetgen, J Li, ... bioRxiv, 2020.06. 02.130104, 2020 | 2 | 2020 |
| Telomere dysfunction alters intestinal stem cell dynamics to promote cancer KA LaBella, WH Hsu, J Li, Y Qi, Y Liu, J Liu, CC Wu, Y Liu, Z Song, Y Lin, ... Developmental cell 59 (11), 1475-1486. e5, 2024 | 1 | 2024 |
| Abstract LB-125: KDM5D as a novel gender-specific gene target for metastatic colorectal cancer J Li, Z Lan, AY Wang, R DePinho Cancer Research 79 (13_Supplement), LB-125-LB-125, 2019 | 1 | 2019 |
| The Y of cancer sex differences J Li, RA DePinho Clinical and Translational Medicine 13 (9), e1402, 2023 | | 2023 |
