Revolutionizing DNA repair research and cancer therapy with CRISPR–Cas screens SW Awwad, A Serrano-Benitez, JC Thomas, V Gupta, SP Jackson Nature Reviews Molecular Cell Biology 24 (7), 477-494, 2023 | 56 | 2023 |
Parallel CRISPR-Cas9 screens clarify impacts of p53 on screen performance AR Bowden, DA Morales-Juarez, M Sczaniecka-Clift, MM Agudo, ... Elife 9, e55325, 2020 | 52 | 2020 |
Loss of Cyclin C or CDK8 provides ATR inhibitor resistance by suppressing transcription-associated replication stress RL Lloyd, V Urban, F Muñoz-Martínez, I Ayestaran, JC Thomas, ... Nucleic acids research 49 (15), 8665-8683, 2021 | 36 | 2021 |
SOX9 maintains human foetal lung tip progenitor state by enhancing WNT and RTK signalling D Sun, O Llora Batlle, J van den Ameele, JC Thomas, P He, K Lim, ... The EMBO Journal 41 (21), e111338, 2022 | 26 | 2022 |
Isolation and characterization of metaldehyde‐degrading bacteria from domestic soils JC Thomas, T Helgason, CJ Sinclair, JWB Moir Microbial Biotechnology 10 (6), 1824-1829, 2017 | 25 | 2017 |
Genomic basis for pesticide degradation revealed by selection, isolation and characterisation of a library of metaldehyde-degrading strains from soil V Castro-Gutiérrez, E Fuller, JC Thomas, CJ Sinclair, S Johnson, ... Soil Biology and Biochemistry 142, 107702, 2020 | 21 | 2020 |
Unrepaired base excision repair intermediates in template DNA strands trigger replication fork collapse and PARP inhibitor sensitivity A Serrano‐Benitez, SE Wells, L Drummond‐Clarke, LC Russo, ... The EMBO Journal 42 (18), e113190, 2023 | 18 | 2023 |
RAD54L2 counters TOP2-DNA adducts to promote genome stability G D’Alessandro, DA Morales-Juarez, SL Richards, KC Nitiss, ... Science Advances 9 (49), eadl2108, 2023 | 10 | 2023 |
Australian secondary mathematics teacher shortfalls: A deepening crisis M O’Connor, J Thomas AMSI Occasional Paper). Australian Mathematical Sciences Institute …, 2019 | 7 | 2019 |
An organoid CRISPRi screen revealed that SOX9 primes human fetal lung tip progenitors to receive WNT and RTK signals D Sun, OL Batlle, J van den Ameele, JC Thomas, P He, K Lim, W Tang, ... BioRxiv, 2022.01. 27.478034, 2022 | 5 | 2022 |
The molecular basis for the biotic degradation of metaldehyde JC Thomas University of York, 2016 | 3 | 2016 |
Genome-aware annotation of CRISPR guides validates targets in variant cell lines and enhances discovery in screens S Lam, JC Thomas, SP Jackson Genome Medicine 16 (1), 139, 2024 | | 2024 |
RAD54L2 mediates a novel mechanism to counter TOP2-DNA adducts G D'Alessandro, D Morales-Juarez, S Richards, A Serrano-Benitez, ... American Association for the Advancement of Science, 2023 | | 2023 |