| An inhibitor of tau hyperphosphorylation prevents severe motor impairments in tau transgenic mice S Le Corre, HW Klafki, N Plesnila, G Hübinger, A Obermeier, H Sahagún, ... Proceedings of the National Academy of Sciences 103 (25), 9673-9678, 2006 | 298 | 2006 |
| Solid-phase synthesis and combinatorial technologies P Seneci John Wiley & Sons, 2003 | 291 | 2003 |
| Novel SMAC-mimetics synergistically stimulate melanoma cell death in combination with TRAIL and Bortezomib D Lecis, C Drago, L Manzoni, P Seneci, C Scolastico, E Mastrangelo, ... British journal of cancer 102 (12), 1707-1716, 2010 | 104 | 2010 |
| A combinatorial approach to [1, 5] benzothiazepine derivatives as potential antibacterial agents F Micheli, F Degiorgis, A Feriani, A Paio, A Pozzan, P Zarantonello, ... Journal of Combinatorial Chemistry 3 (2), 224-228, 2001 | 100 | 2001 |
| Stimulus-responsive liposomes for biomedical applications AI Antoniou, S Giofrè, P Seneci, D Passarella, S Pellegrino Drug discovery today 26 (8), 1794-1824, 2021 | 91 | 2021 |
| Solid supported chiral auxiliaries in asymmetric synthesis. Part 2: Catalysis of 1, 3-dipolar cycloadditions by Mg (II) cation G Faita, A Paio, P Quadrelli, F Rancati, P Seneci Tetrahedron 57 (39), 8313-8322, 2001 | 91 | 2001 |
| Dihydrotanshinone-I interferes with the RNA-binding activity of HuR affecting its post-transcriptional function VG D’Agostino, P Lal, B Mantelli, C Tiedje, C Zucal, N Thongon, ... Scientific reports 5 (1), 16478, 2015 | 90 | 2015 |
| Regulation of HuR structure and function by dihydrotanshinone-I P Lal, L Cerofolini, VG D’Agostino, C Zucal, C Fuccio, I Bonomo, E Dassi, ... Nucleic acids research 45 (16), 9514-9527, 2017 | 85 | 2017 |
| Peptide aldehydes as inhibitors of HIV protease E Sarubbi, PF Seneci, MR Angelastro, NP Peet, M Denaro, K Islam FEBS letters 319 (3), 253-256, 1993 | 76 | 1993 |
| Designing Smac-mimetics as antagonists of XIAP, cIAP1, and cIAP2 F Cossu, E Mastrangelo, M Milani, G Sorrentino, D Lecis, D Delia, ... Biochemical and biophysical research communications 378 (2), 162-167, 2009 | 74 | 2009 |
| (4S)-p-Hydroxybenzyl-1, 3-oxazolidin-2-one as a solid-supported chiral auxiliary in asymmetric 1, 3-dipolar cycloadditions G Faita, A Paio, P Quadrelli, F Rancati, P Seneci Tetrahedron Letters 41 (8), 1265-1269, 2000 | 71 | 2000 |
| Synthesis and antimicrobial activity of oxazolidin-2-ones and related heterocycles P Seneci, M Caspani, F Ripamonti, R Ciabatti Journal of the Chemical Society, Perkin Transactions 1, 2345-2351, 1994 | 59 | 1994 |
| Interfering with HuR–RNA interaction: design, synthesis and biological characterization of tanshinone mimics as novel, effective HuR inhibitors L Manzoni, C Zucal, DD Maio, VG D’Agostino, N Thongon, I Bonomo, ... Journal of Medicinal Chemistry 61 (4), 1483-1498, 2018 | 58 | 2018 |
| Immobilized benzylpenicillin acylase: application to the synthesis of optically active forms of carnitin and propranalol C Fuganti, P Grasselli, PF Seneci, S Servi, P Casati Tetrahedron letters 27 (18), 2061-2062, 1986 | 58 | 1986 |
| Smac mimetics induce inflammation and necrotic tumour cell death by modulating macrophage activity D Lecis, M De Cesare, P Perego, A Conti, E Corna, C Drago, P Seneci, ... Cell death & disease 4 (11), e920-e920, 2013 | 55 | 2013 |
| Stereoselective synthesis of conformationally constrained cyclohexanediols: a set of molecular scaffolds for the synthesis of glycomimetics A Bernardi, D Arosio, L Manzoni, F Micheli, A Pasquarello, P Seneci The Journal of Organic Chemistry 66 (19), 6209-6216, 2001 | 55 | 2001 |
| Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis L Muzio, R Sirtori, D Gornati, S Eleuteri, A Fossaghi, D Brancaccio, ... Nature communications 11 (1), 3848, 2020 | 54 | 2020 |
| Structural basis for bivalent Smac-mimetics recognition in the IAP protein family F Cossu, M Milani, E Mastrangelo, P Vachette, F Servida, D Lecis, ... Journal of molecular biology 392 (3), 630-644, 2009 | 54 | 2009 |
| Rational design, synthesis and characterization of potent, non-peptidic Smac mimics/XIAP inhibitors as proapoptotic agents for cancer therapy P Seneci, A Bianchi, C Battaglia, L Belvisi, M Bolognesi, A Caprini, ... Bioorganic & medicinal chemistry 17 (16), 5834-5856, 2009 | 53 | 2009 |
| Targeting the X-linked inhibitor of apoptosis protein through 4-substituted azabicyclo [5.3. 0] alkane smac mimetics. Structure, activity, and recognition principles E Mastrangelo, F Cossu, M Milani, G Sorrentino, D Lecis, D Delia, ... Journal of molecular biology 384 (3), 673-689, 2008 | 49 | 2008 |
