| Allele-specific HLA loss and immune escape in lung cancer evolution N McGranahan, R Rosenthal, CT Hiley, AJ Rowan, TBK Watkins, ... Cell 171 (6), 1259-1271. e11, 2017 | 1302 | 2017 |
| Tumorigenicity and genetic profiling of circulating tumor cells in small-cell lung cancer CL Hodgkinson, CJ Morrow, Y Li, RL Metcalf, DG Rothwell, F Trapani, ... Nature medicine 20 (8), 897-903, 2014 | 842 | 2014 |
| Fc effector function contributes to the activity of human anti-CTLA-4 antibodies FA Vargas, AJS Furness, K Litchfield, K Joshi, R Rosenthal, E Ghorani, ... Cancer cell 33 (4), 649-663. e4, 2018 | 596 | 2018 |
| Fc-optimized anti-CD25 depletes tumor-infiltrating regulatory T cells and synergizes with PD-1 blockade to eradicate established tumors FA Vargas, AJS Furness, I Solomon, K Joshi, L Mekkaoui, MH Lesko, ... Immunity 46 (4), 577-586, 2017 | 461 | 2017 |
| The clinical efficacy of first-generation carcinoembryonic antigen (CEACAM5)-specific CAR T cells is limited by poor persistence and transient pre-conditioning-dependent … FC Thistlethwaite, DE Gilham, RD Guest, DG Rothwell, M Pillai, DJ Burt, ... Cancer Immunology, Immunotherapy 66, 1425-1436, 2017 | 400 | 2017 |
| The crystal structure of the human DNA repair endonuclease HAP1 suggests the recognition of extra‐helical deoxyribose at DNA abasic sites MA Gorman, S Morera, DG Rothwell, E de La Fortelle, CD Mol, JA Tainer, ... The EMBO journal, 1997 | 381 | 1997 |
| Cloning and characterization of a functional human homolog of Escherichia coli endonuclease III R Aspinwall, DG Rothwell, T Roldan-Arjona, C Anselmino, CJ Ward, ... Proceedings of the National Academy of Sciences 94 (1), 109-114, 1997 | 349 | 1997 |
| Molecular analysis of circulating tumor cells identifies distinct copy-number profiles in patients with chemosensitive and chemorefractory small-cell lung cancer L Carter, DG Rothwell, B Mesquita, C Smowton, HS Leong, ... Nature medicine 23 (1), 114-119, 2017 | 328 | 2017 |
| Liquid biopsy-based biomarkers of treatment response and resistance E Kilgour, DG Rothwell, G Brady, C Dive Cancer cell 37 (4), 485-495, 2020 | 315 | 2020 |
| Utility of ctDNA to support patient selection for early phase clinical trials: the TARGET study DG Rothwell, M Ayub, N Cook, F Thistlethwaite, L Carter, E Dean, N Smith, ... Nature medicine 25 (5), 738-743, 2019 | 262 | 2019 |
| Vasculogenic mimicry in small cell lung cancer SC Williamson, RL Metcalf, F Trapani, S Mohan, J Antonello, B Abbott, ... Nature communications 7 (1), 13322, 2016 | 260 | 2016 |
| Application of sequencing, liquid biopsies, and patient-derived xenografts for personalized medicine in melanoma MR Girotti, G Gremel, R Lee, E Galvani, D Rothwell, A Viros, AK Mandal, ... Cancer discovery 6 (3), 286-299, 2016 | 242 | 2016 |
| Circulating tumour DNA—looking beyond the blood A Tivey, M Church, D Rothwell, C Dive, N Cook Nature reviews clinical oncology 19 (9), 600-612, 2022 | 198 | 2022 |
| Pulmonary venous circulating tumor cell dissemination before tumor resection and disease relapse F Chemi, DG Rothwell, N McGranahan, S Gulati, C Abbosh, SP Pearce, ... Nature medicine 25 (10), 1534-1539, 2019 | 194 | 2019 |
| Targeted immunotherapy of cancer with CAR T cells: achievements and challenges G Lipowska-Bhalla, DE Gilham, RE Hawkins, DG Rothwell Cancer Immunology, Immunotherapy 61, 953-962, 2012 | 160 | 2012 |
| Antibodies against endogenous retroviruses promote lung cancer immunotherapy KW Ng, J Boumelha, KSS Enfield, J Almagro, H Cha, O Pich, T Karasaki, ... Nature 616 (7957), 563-573, 2023 | 154 | 2023 |
| Clinical evaluation of a novel microfluidic device for epitope-independent enrichment of circulating tumour cells in patients with small cell lung cancer J Chudziak, DJ Burt, S Mohan, DG Rothwell, B Mesquita, J Antonello, ... Analyst 141 (2), 669-678, 2016 | 137 | 2016 |
| Multicenter evaluation of circulating cell-free DNA extraction and downstream analyses for the development of standardized (pre) analytical work flows R Lampignano, MHD Neumann, S Weber, V Kloten, A Herdean, T Voss, ... Clinical chemistry 66 (1), 149-160, 2020 | 135 | 2020 |
| Tumourigenic non-small-cell lung cancer mesenchymal circulating tumour cells: a clinical case study CJ Morrow, F Trapani, RL Metcalf, G Bertolini, CL Hodgkinson, ... Annals of Oncology 27 (6), 1155-1160, 2016 | 110 | 2016 |
| cfDNA methylome profiling for detection and subtyping of small cell lung cancers F Chemi, SP Pearce, A Clipson, SM Hill, AM Conway, SA Richardson, ... Nature Cancer 3 (10), 1260-1270, 2022 | 88 | 2022 |
Caroline DiveProfessor of Pharmacology, University of ManchesterE-mailová adresa ověřena na: cruk.manchester.ac.uk
