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Timothy Luongo
Timothy Luongo
Spark Therapeutics
E-mailová adresa ověřena na: sparktx.com
Název
Citace
Citace
Rok
Embryonic stem cell–derived exosomes promote endogenous repair mechanisms and enhance cardiac function following myocardial infarction
M Khan, E Nickoloff, T Abramova, J Johnson, SK Verma, P Krishnamurthy, ...
Circulation research 117 (1), 52-64, 2015
7852015
The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition
TS Luongo, JP Lambert, A Yuan, X Zhang, P Gross, J Song, ...
Cell reports 12 (1), 23-34, 2015
4102015
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability
TS Luongo, JP Lambert, P Gross, M Nwokedi, AA Lombardi, ...
Nature 545 (7652), 93-97, 2017
3982017
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies
T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ...
Immunity 39 (2), 245-258, 2013
3912013
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Cell 161 (6), 1280-1292, 2015
3422015
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease
P Jadiya, DW Kolmetzky, D Tomar, A Di Meco, AA Lombardi, JP Lambert, ...
Nature communications 10 (1), 3885, 2019
2842019
SLC25A51 is a mammalian mitochondrial NAD+ transporter
TS Luongo, JM Eller, MJ Lu, M Niere, F Raith, C Perry, MR Bornstein, ...
Nature 588 (7836), 174-179, 2020
2532020
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics
D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ...
Cell reports 15 (8), 1673-1685, 2016
2302016
The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis
N Jaiswal, MG Gavin, WJ Quinn Iii, TS Luongo, RG Gelfer, JA Baur, ...
Molecular metabolism 28, 1-13, 2019
1662019
Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation
AA Lombardi, AA Gibb, E Arif, DW Kolmetzky, D Tomar, TS Luongo, ...
Nature communications 10 (1), 4509, 2019
1422019
MCUB regulates the molecular composition of the mitochondrial calcium uniporter channel to limit mitochondrial calcium overload during stress
JP Lambert, TS Luongo, D Tomar, P Jadiya, E Gao, X Zhang, ...
Circulation 140 (21), 1720-1733, 2019
1332019
Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection
P Acharya, WD Tolbert, N Gohain, X Wu, L Yu, T Liu, W Huang, C Huang, ...
Journal of virology 88 (21), 12895-12906, 2014
1232014
The debate continues–what is the role of MCU and mitochondrial calcium uptake in the heart?
JF Garbincius, TS Luongo, JW Elrod
Journal of molecular and cellular cardiology 143, 163-174, 2020
432020
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function
P Dierickx, K Zhu, BJ Carpenter, C Jiang, MW Vermunt, Y Xiao, ...
Nature cardiovascular research 1 (1), 45-58, 2022
422022
Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry
P Acharya, C Dogo-Isonagie, JM LaLonde, SN Lam, GJ Leslie, ...
American Chemical Society, 2011
382011
Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 Å cocrystal structure of gp120 and M48U1
P Acharya, TS Luongo, MK Louder, K McKee, Y Yang, Y Do Kwon, ...
Structure 21 (6), 1018-1029, 2013
342013
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia
LM Paolella, S Mukherjee, CM Tran, B Bellaver, M Hugo, TS Luongo, ...
Molecular metabolism 32, 136-147, 2020
302020
Heavy chain-only IgG2b llama antibody effects near-pan HIV-1 neutralization by recognizing a CD4-induced epitope that includes elements of coreceptor-and CD4-binding sites
P Acharya, TS Luongo, IS Georgiev, J Matz, SD Schmidt, MK Louder, ...
Journal of virology 87 (18), 10173-10181, 2013
302013
Design of epitope-specific probes for sera analysis and antibody isolation
I Georgiev, P Acharya, SD Schmidt, Y Li, D Wycuff, G Ofek, N Doria-Rose, ...
Retrovirology 9, 1-1, 2012
302012
Program NCS
T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ...
Mullikin JC, Gray MD, Stamatatos L, Burton DR, Koff WC, Cohen MS, Haynes BF …, 2015
252015
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Články 1–20