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The mitochondrial calcium uniporter matches energetic supply with cardiac workload during stress and modulates permeability transition TS Luongo, JP Lambert, A Yuan, X Zhang, P Gross, J Song, ... Cell reports 12 (1), 23-34, 2015 | 410 | 2015 |
The mitochondrial Na+/Ca2+ exchanger is essential for Ca2+ homeostasis and viability TS Luongo, JP Lambert, P Gross, M Nwokedi, AA Lombardi, ... Nature 545 (7652), 93-97, 2017 | 398 | 2017 |
Multidonor analysis reveals structural elements, genetic determinants, and maturation pathway for HIV-1 neutralization by VRC01-class antibodies T Zhou, J Zhu, X Wu, S Moquin, B Zhang, P Acharya, IS Georgiev, ... Immunity 39 (2), 245-258, 2013 | 391 | 2013 |
Structural repertoire of HIV-1-neutralizing antibodies targeting the CD4 supersite in 14 donors T Zhou, RM Lynch, L Chen, P Acharya, X Wu, NA Doria-Rose, MG Joyce, ... Cell 161 (6), 1280-1292, 2015 | 342 | 2015 |
Impaired mitochondrial calcium efflux contributes to disease progression in models of Alzheimer’s disease P Jadiya, DW Kolmetzky, D Tomar, A Di Meco, AA Lombardi, JP Lambert, ... Nature communications 10 (1), 3885, 2019 | 284 | 2019 |
SLC25A51 is a mammalian mitochondrial NAD+ transporter TS Luongo, JM Eller, MJ Lu, M Niere, F Raith, C Perry, MR Bornstein, ... Nature 588 (7836), 174-179, 2020 | 253 | 2020 |
MCUR1 is a scaffold factor for the MCU complex function and promotes mitochondrial bioenergetics D Tomar, Z Dong, S Shanmughapriya, DA Koch, T Thomas, NE Hoffman, ... Cell reports 15 (8), 1673-1685, 2016 | 230 | 2016 |
The role of skeletal muscle Akt in the regulation of muscle mass and glucose homeostasis N Jaiswal, MG Gavin, WJ Quinn Iii, TS Luongo, RG Gelfer, JA Baur, ... Molecular metabolism 28, 1-13, 2019 | 166 | 2019 |
Mitochondrial calcium exchange links metabolism with the epigenome to control cellular differentiation AA Lombardi, AA Gibb, E Arif, DW Kolmetzky, D Tomar, TS Luongo, ... Nature communications 10 (1), 4509, 2019 | 142 | 2019 |
MCUB regulates the molecular composition of the mitochondrial calcium uniporter channel to limit mitochondrial calcium overload during stress JP Lambert, TS Luongo, D Tomar, P Jadiya, E Gao, X Zhang, ... Circulation 140 (21), 1720-1733, 2019 | 133 | 2019 |
Structural definition of an antibody-dependent cellular cytotoxicity response implicated in reduced risk for HIV-1 infection P Acharya, WD Tolbert, N Gohain, X Wu, L Yu, T Liu, W Huang, C Huang, ... Journal of virology 88 (21), 12895-12906, 2014 | 123 | 2014 |
The debate continues–what is the role of MCU and mitochondrial calcium uptake in the heart? JF Garbincius, TS Luongo, JW Elrod Journal of molecular and cellular cardiology 143, 163-174, 2020 | 43 | 2020 |
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function P Dierickx, K Zhu, BJ Carpenter, C Jiang, MW Vermunt, Y Xiao, ... Nature cardiovascular research 1 (1), 45-58, 2022 | 42 | 2022 |
Structure-based identification and neutralization mechanism of tyrosine sulfate mimetics that inhibit HIV-1 entry P Acharya, C Dogo-Isonagie, JM LaLonde, SN Lam, GJ Leslie, ... American Chemical Society, 2011 | 38 | 2011 |
Structural basis for highly effective HIV-1 neutralization by CD4-mimetic miniproteins revealed by 1.5 Å cocrystal structure of gp120 and M48U1 P Acharya, TS Luongo, MK Louder, K McKee, Y Yang, Y Do Kwon, ... Structure 21 (6), 1018-1029, 2013 | 34 | 2013 |
mTORC1 restrains adipocyte lipolysis to prevent systemic hyperlipidemia LM Paolella, S Mukherjee, CM Tran, B Bellaver, M Hugo, TS Luongo, ... Molecular metabolism 32, 136-147, 2020 | 30 | 2020 |
Heavy chain-only IgG2b llama antibody effects near-pan HIV-1 neutralization by recognizing a CD4-induced epitope that includes elements of coreceptor-and CD4-binding sites P Acharya, TS Luongo, IS Georgiev, J Matz, SD Schmidt, MK Louder, ... Journal of virology 87 (18), 10173-10181, 2013 | 30 | 2013 |
Design of epitope-specific probes for sera analysis and antibody isolation I Georgiev, P Acharya, SD Schmidt, Y Li, D Wycuff, G Ofek, N Doria-Rose, ... Retrovirology 9, 1-1, 2012 | 30 | 2012 |
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