Neuron-specific proteotoxicity of mutant ataxin-3 in C. elegans : rescue by the DAF-16 and HSF-1 pathways A Teixeira-Castro, M Ailion, A Jalles, HR Brignull, JL Vilaça, N Dias, ... Human molecular genetics 20 (15), 2996-3009, 2011 | 149 | 2011 |
Chronic treatment with 17-DMAG improves balance and coordination in a new mouse model of Machado-Joseph disease A Silva-Fernandes, S Duarte-Silva, A Neves-Carvalho, M Amorim, ... Neurotherapeutics 11 (2), 433-449, 2014 | 124 | 2014 |
Astrocytic signaling supports hippocampal–prefrontal theta synchronization and cognitive function VM Sardinha, S Guerra‐Gomes, I Caetano, G Tavares, M Martins, JS Reis, ... Glia 65 (12), 1944-1960, 2017 | 105 | 2017 |
Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease A Teixeira-Castro, A Jalles, S Esteves, S Kang, L da Silva Santos, ... Brain 138 (11), 3221-3237, 2015 | 92 | 2015 |
NEDD8: a new ataxin-3 interactor A Ferro, AL Carvalho, A Teixeira-Castro, C Almeida, RJ Tomé, L Cortes, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1773 (11), 1619-1627, 2007 | 92 | 2007 |
Development and characterization of a PHB‐HV‐based 3 D scaffold for a tissue engineering and cell‐therapy combinatorial approach for spinal cord injury regeneration S Ribeiro‐Samy, NA Silva, VM Correlo, JS Fraga, L Pinto, ... Macromolecular bioscience 13 (11), 1576-1592, 2013 | 66 | 2013 |
Monoamine deficits in the brain of methyl-CpG binding protein 2 null mice suggest the involvement of the cerebral cortex in early stages of Rett syndrome M Santos, T Summavielle, A Teixeira-Castro, A Silva-Fernandes, ... Neuroscience 170 (2), 453-467, 2010 | 64 | 2010 |
From pathogenesis to novel therapeutics for spinocerebellar ataxia type 3: evading potholes on the way to translation JD Da Silva, A Teixeira-Castro, P Maciel Neurotherapeutics 16 (4), 1009-1031, 2019 | 57 | 2019 |
GST-4-Dependent Suppression of Neurodegeneration in C. elegans Models of Parkinson’s and Machado-Joseph Disease by Rapeseed Pomace Extract … F Pohl, A Teixeira-Castro, MD Costa, V Lindsay, J Fiúza-Fernandes, ... Frontiers in neuroscience 13, 1091, 2019 | 55 | 2019 |
Absence of Ataxin-3 Leads to Enhanced Stress Response in C. elegans AJ Rodrigues, A Neves-Carvalho, A Teixeira-Castro, A Rokka, G Corthals, ... PLoS One 6 (4), e18512, 2011 | 39 | 2011 |
Exclusion of mutations in the PRNP, JPH3, TBP, ATN1, CREBBP, POU3F2 and FTL genes as a cause of disease in Portuguese patients with a Huntington-like phenotype MC Costa, A Teixeira-Castro, M Constante, M Magalhaes, P Magalhaes, ... Journal of human genetics 51 (8), 645-651, 2006 | 39 | 2006 |
Neuroprotective effects of creatine in the CMVMJD135 mouse model of spinocerebellar ataxia type 3 S Duarte‐Silva, A Neves‐Carvalho, C Soares‐Cunha, JM Silva, ... Movement Disorders 33 (5), 815-826, 2018 | 35 | 2018 |
Combined therapy with m-TOR-dependent and-independent autophagy inducers causes neurotoxicity in a mouse model of Machado–Joseph disease S Duarte-Silva, A Silva-Fernandes, A Neves-Carvalho, C Soares-Cunha, ... Neuroscience 313, 162-173, 2016 | 32 | 2016 |
Lithium chloride therapy fails to improve motor function in a transgenic mouse model of Machado-Joseph disease S Duarte-Silva, A Neves-Carvalho, C Soares-Cunha, A Teixeira-Castro, ... The Cerebellum 13, 713-727, 2014 | 31 | 2014 |
Limited effect of chronic valproic acid treatment in a mouse model of Machado-Joseph disease S Esteves, S Duarte-Silva, L Naia, A Neves-Carvalho, A Teixeira-Castro, ... PLoS One 10 (10), e0141610, 2015 | 29 | 2015 |
Citalopram reduces aggregation of ATXN3 in a YAC transgenic mouse model of Machado-Joseph disease NS Ashraf, S Duarte-Silva, ED Shaw, P Maciel, HL Paulson, ... Molecular neurobiology 56, 3690-3701, 2019 | 27 | 2019 |
Phospholipase D functional ablation has a protective effect in an Alzheimer’s disease Caenorhabditis elegans model FV Bravo, J Da Silva, RB Chan, G Di Paolo, A Teixeira-Castro, TG Oliveira Scientific Reports 8 (1), 3540, 2018 | 24 | 2018 |
Preclinical evidence supporting early initiation of citalopram treatment in Machado-Joseph disease S Esteves, S Oliveira, S Duarte-Silva, D Cunha-Garcia, A Teixeira-Castro, ... Molecular neurobiology 56, 3626-3637, 2019 | 20 | 2019 |
Mesenchymal stem cell secretome protects against alpha-synuclein-induced neurodegeneration in a Caenorhabditis elegans model of Parkinson's disease CR Marques, J Pereira-Sousa, FG Teixeira, RA Sousa, A Teixeira-Castro, ... Cytotherapy 23 (10), 894-901, 2021 | 16 | 2021 |
A network approach to discerning the identities of C. elegans in a free moving population PB Winter, RM Brielmann, NP Timkovich, HT Navarro, A Teixeira-Castro, ... Scientific reports 6 (1), 34859, 2016 | 16 | 2016 |