| Acetylcholinesterase accelerates assembly of amyloid-β-peptides into Alzheimer's fibrils: possible role of the peripheral site of the enzyme NC Inestrosa, A Alvarez, CA Perez, RD Moreno, M Vicente, C Linker, ... Neuron 16 (4), 881-891, 1996 | 1331 | 1996 |
| Metalloenzyme-like activity of Alzheimer's disease β-amyloid: Cu-dependent catalytic conversion of dopamine, cholesterol, and biological reducing agents to neurotoxic H2O2 C Opazo, X Huang, RA Cherny, RD Moir, AE Roher, AR White, R Cappai, ... Journal of Biological Chemistry 277 (43), 40302-40308, 2002 | 791 | 2002 |
| Emerging roles of Wnts in the adult nervous system NC Inestrosa, E Arenas Nature Reviews Neuroscience 11 (2), 77-86, 2010 | 773 | 2010 |
| Settlement of benthic marine invertebrates SR Rodriguez, FP Ojeda, NC Inestrosa Marine ecology progress series. Oldendorf 97 (2), 193-207, 1993 | 765 | 1993 |
| A structural motif of acetylcholinesterase that promotes amyloid β-peptide fibril formation GV De Ferrari, MA Canales, I Shin, LM Weiner, I Silman, NC Inestrosa Biochemistry 40 (35), 10447-10457, 2001 | 523 | 2001 |
| The role of oxidative stress in the toxicity induced by amyloid β-peptide in Alzheimer’s disease S Miranda, C Opazo, LF Larrondo, FJ Muñoz, F Ruiz, F Leighton, ... Progress in neurobiology 62 (6), 633-648, 2000 | 522 | 2000 |
| Activation of Wnt signaling rescues neurodegeneration and behavioral impairments induced by β-amyloid fibrils GV De Ferrari, MA Chacon, MI Barria, JL Garrido, JA Godoy, G Olivares, ... Molecular psychiatry 8 (2), 195-208, 2003 | 463 | 2003 |
| Stable complexes involving acetylcholinesterase and amyloid-β peptide change the biochemical properties of the enzyme and increase the neurotoxicity of Alzheimer’s fibrils A Alvarez, R Alarcon, C Opazo, EO Campos, FJ Munoz, FH Calderon, ... Journal of Neuroscience 18 (9), 3213-3223, 1998 | 443 | 1998 |
| The α-Helical to β-Strand Transition in the Amino-terminal Fragment of the Amyloid β-Peptide Modulates Amyloid Formation∗ C Soto, EM Castano, B Frangione, NC Inestrosa Journal of Biological Chemistry 270 (7), 3063-3067, 1995 | 428 | 1995 |
| Wnt signaling function in Alzheimer’s disease GV De Ferrari, NC Inestrosa Brain research reviews 33 (1), 1-12, 2000 | 383 | 2000 |
| Acetylcholinesterase promotes the aggregation of amyloid-β-peptide fragments by forming a complex with the growing fibrils A Alvarez, C Opazo, R Alarcón, J Garrido, NC Inestrosa Journal of molecular biology 272 (3), 348-361, 1997 | 382 | 1997 |
| Activation of Wnt signaling by lithium and rosiglitazone reduced spatial memory impairment and neurodegeneration in brains of an APPswe/PSEN1ΔE9 mouse model of Alzheimer's disease EM Toledo, NC Inestrosa Molecular psychiatry 15 (3), 272-285, 2010 | 362 | 2010 |
| Platelets are the primary source of amyloid β-peptide in human blood M Chen, NC Inestrosa, GS Ross, HL Fernandez Biochemical and biophysical research communications 213 (1), 96-103, 1995 | 356 | 1995 |
| Wnt signaling in the nervous system and in Alzheimer's disease NC Inestrosa, L Varela-Nallar Journal of molecular cell biology 6 (1), 64-74, 2014 | 354 | 2014 |
| Amyloid–cholinesterase interactions: implications for Alzheimer’s disease NC Inestrosa, MC Dinamarca, A Alvarez The FEBS journal 275 (4), 625-632, 2008 | 327 | 2008 |
| Peroxisome proliferator-activated receptor γ up-regulates the Bcl-2 anti-apoptotic protein in neurons and induces mitochondrial stabilization and protection against oxidative … K Fuenzalida, R Quintanilla, P Ramos, D Piderit, RA Fuentealba, ... Journal of Biological Chemistry 282 (51), 37006-37015, 2007 | 320 | 2007 |
| Wnt-3a overcomes β-amyloid toxicity in rat hippocampal neurons AR Alvarez, JA Godoy, K Mullendorff, GH Olivares, M Bronfman, ... Experimental cell research 297 (1), 186-196, 2004 | 313 | 2004 |
| WNT signaling in neuronal maturation and synaptogenesis SB Rosso, NC Inestrosa Frontiers in cellular neuroscience 7, 103, 2013 | 296 | 2013 |
| Wnt signaling in neuroprotection and stem cell differentiation EM Toledo, M Colombres, NC Inestrosa Progress in neurobiology 86 (3), 281-296, 2008 | 294 | 2008 |
| Wnt-5a/JNK signaling promotes the clustering of PSD-95 in hippocampal neurons GG Farías, IE Alfaro, W Cerpa, CP Grabowski, JA Godoy, C Bonansco, ... Journal of Biological Chemistry 284 (23), 15857-15866, 2009 | 269 | 2009 |
