Blockade of the PD-1/PD-L1 axis augments lysis of AML cells by the CD33/CD3 BiTE antibody construct AMG 330: reversing a T-cell-induced immune escape mechanism C Krupka, P Kufer, R Kischel, G Zugmaier, FS Lichtenegger, T Köhnke, ... Leukemia 30 (2), 484-491, 2016 | 279 | 2016 |
CD33 target validation and sustained depletion of AML blasts in long-term cultures by the bispecific T-cell–engaging antibody AMG 330 C Krupka, P Kufer, R Kischel, G Zugmaier, J Bögeholz, T Köhnke, ... Blood, The Journal of the American Society of Hematology 123 (3), 356-365, 2014 | 239 | 2014 |
Increase of PD-L1 expressing B-precursor ALL cells in a patient resistant to the CD19/CD3-bispecific T cell engager antibody blinatumomab T Köhnke, C Krupka, J Tischer, T Knösel, M Subklewe Journal of hematology & oncology 8, 1-5, 2015 | 186 | 2015 |
Recent developments in immunotherapy of acute myeloid leukemia FS Lichtenegger, C Krupka, S Haubner, T Köhnke, M Subklewe Journal of hematology & oncology 10, 1-20, 2017 | 177 | 2017 |
An advanced preclinical mouse model for acute myeloid leukemia using patients' cells of various genetic subgroups and in vivo bioluminescence imaging B Vick, M Rothenberg, N Sandhöfer, M Carlet, C Finkenzeller, C Krupka, ... PloS one 10 (3), e0120925, 2015 | 124 | 2015 |
Tyrosine kinase inhibition increases the cell surface localization of FLT3-ITD and enhances FLT3-directed immunotherapy of acute myeloid leukemia K Reiter, H Polzer, C Krupka, A Maiser, B Vick, M Rothenberg-Thurley, ... Leukemia 32 (2), 313-322, 2018 | 96 | 2018 |
Immunotherapy for acute myeloid leukemia FS Lichtenegger, C Krupka, T Köhnke, M Subklewe Seminars in hematology 52 (3), 207-214, 2015 | 76 | 2015 |
Targeting CD157 in AML using a novel, Fc-engineered antibody construct C Krupka, FS Lichtenegger, T Köhnke, J Bögeholz, V Bücklein, M Roiss, ... Oncotarget 8 (22), 35707, 2017 | 38 | 2017 |
SIRPα-antibody fusion proteins stimulate phagocytosis and promote elimination of acute myeloid leukemia cells LP Ponce, NC Fenn, N Moritz, C Krupka, JH Kozik, K Lauber, M Subklewe, ... Oncotarget 8 (7), 11284, 2017 | 34 | 2017 |
Induction of antigen-specific T-cell responses through dendritic cell vaccination in AML: results of a phase I/II trial and ex vivo enhancement by checkpoint blockade FS Lichtenegger, K Deiser, M Rothe, FM Schnorfeil, C Krupka, ... Blood 128 (22), 764, 2016 | 14 | 2016 |