Andreas Kraemer

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39 článků

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Stefan KnappUniversity of FrankfurtE-mailová adresa ověřena na: pharmchem.uni-frankfurt.de
Andreas C. JoergerStructural Genomics Consortium (SGC), Institute of Pharmaceutical Chemistry, Goethe UniversityE-mailová adresa ověřena na: pharmchem.uni-frankfurt.de
Benedict-Tilman BergerPostDoc Biochemistry, Goethe University FrankfurtE-mailová adresa ověřena na: chemie.uni-frankfurt.de
Franz-Josef Meyer-AlmesProfessor for Biochemistry, University of Applied Sciences DarmstadtE-mailová adresa ověřena na: h-da.de
Cheryl ArrowsmithSenior Scientist, Princess Margaret Cancer Centre & Professor of Medical Biophysics, University of TorontoE-mailová adresa ověřena na: uhnres.utoronto.ca
David HeidenreichGoethe University, FrankfurtE-mailová adresa ověřena na: pharmchem.uni-frankfurt.de
Claire E. WestonImperial College LondonE-mailová adresa ověřena na: imperial.ac.uk
Matthias BaudUniversity of SouthamptonE-mailová adresa ověřena na: soton.ac.uk
Christian MeynersTU DarmstadtE-mailová adresa ověřena na: drugdiscovery.chemie.tu-darmstadt.de
Oleg FedorovUniversity of OxfordE-mailová adresa ověřena na: cmd.ox.ac.uk
Masoud VedadiUniversity of TorontoE-mailová adresa ověřena na: utoronto.ca
Qin WuUniversity of Toronto, SGCE-mailová adresa ověřena na: utoronto.ca
Dr. Stanley (Zhen Jian) Zhou, PhDArsenal Biosciences Inc. (Previously: Princess Margaret Cancer Centre)E-mailová adresa ověřena na: mail.utoronto.ca
Mathieu Lupien, PhD; FRSCSenior Scientist/Professor, Princess Margaret Cancer CentreE-mailová adresa ověřena na: uhn.ca
Kiran NakkaThe Ohio State University, Department of Physiology and Cell BiologyE-mailová adresa ověřena na: osumc.edu
S AcklooUniversity of TorontoE-mailová adresa ověřena na: utoronto.ca
Panagis FilippakopoulosAssociate Professor, Oxford UniversityE-mailová adresa ověřena na: sgc.ox.ac.uk
Genevieve DebloisUniversity of Montreal, IRICE-mailová adresa ověřena na: mail.mcgill.ca
Alan FershtEmeritus Group Leader, MRC Laboratory of Molecular Biology, University of CambridgeE-mailová adresa ověřena na: cam.ac.uk
John SpencerChemistry, University of SussexE-mailová adresa ověřena na: sussex.ac.uk

Sledovat

Andreas Kraemer

Group Leader, Structural Genomics Consortium

E-mailová adresa ověřena na: pharmchem.uni-frankfurt.de

Structural Biology Screening


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
A chemical toolbox for the study of bromodomains and epigenetic signaling Q Wu, D Heidenreich, S Zhou, S Ackloo, A Krämer, K Nakka, ... Nature communications 10 (1), 1915, 2019	135	2019
Exploiting vulnerabilities of SWI/SNF chromatin remodelling complexes for cancer therapy M Wanior, A Krämer, S Knapp, AC Joerger Oncogene 40 (21), 3637-3654, 2021	107	2021
Toward photopharmacological antimicrobial chemotherapy using photoswitchable amidohydrolase inhibitors CE Weston, A Krämer, F Colin, O Yildiz, MGJ Baud, FJ Meyer-Almes, ... ACS Infectious Diseases 3 (2), 152-161, 2017	96	2017
Development of a potent and selective chemical probe for the pleiotropic kinase CK2 CI Wells, DH Drewry, JE Pickett, A Tjaden, A Krämer, S Müller, L Gyenis, ... Cell chemical biology 28 (4), 546-558. e10, 2021	87	2021
Targeting cavity-creating p53 cancer mutations with small-molecule stabilizers: the Y220X paradigm MR Bauer, A Krämer, G Settanni, RN Jones, X Ni, R Khan Tareque, ... ACS Chemical Biology 15 (3), 657-668, 2020	68	2020
Design, synthesis, and evaluation of WD-repeat-containing protein 5 (WDR5) degraders A Dölle, B Adhikari, A Krämer, J Weckesser, N Berner, LM Berger, ... Journal of medicinal chemistry 64 (15), 10682-10710, 2021	64	2021
Pharmacological targeting of MTHFD2 suppresses acute myeloid leukemia by inducing thymidine depletion and replication stress N Bonagas, NMS Gustafsson, M Henriksson, P Marttila, R Gustafsson, ... Nature cancer 3 (2), 156-172, 2022	45	2022
Optimization of pyrazolo [1, 5-a] pyrimidines lead to the identification of a highly selective casein kinase 2 inhibitor A Krämer, CG Kurz, BT Berger, IE Celik, A Tjaden, FA Greco, S Knapp, ... European journal of medicinal chemistry 208, 112770, 2020	43	2020
Tracking the PROTAC degradation pathway in living cells highlights the importance of ternary complex measurement for PROTAC optimization MP Schwalm, A Krämer, A Dölle, J Weckesser, X Yu, J Jin, K Saxena, ... Cell chemical biology 30 (7), 753-765. e8, 2023	39	2023
Pan-SMARCA/PB1 bromodomain inhibitors and their role in regulating adipogenesis M Wanior, F Preuss, X Ni, A Krämer, S Mathea, T Göbel, ... Journal of medicinal chemistry 63 (23), 14680-14699, 2020	29	2020
Substrate specificity and function of acetylpolyamine amidohydrolases from Pseudomonas aeruginosa A Krämer, J Herzer, J Overhage, FJ Meyer-Almes BMC biochemistry 17, 1-10, 2016	27	2016
A fluorescence lifetime-based binding assay for acetylpolyamine amidohydrolases from Pseudomonas aeruginosa using a [1,3]dioxolo[4,5-f][1,3]benzodioxole … C Meyners, R Wawrzinek, A Krämer, S Hinz, P Wessig, FJ Meyer-Almes Analytical and bioanalytical chemistry 406, 4889-4897, 2014	23	2014
Discovery of Highly Selective Inhibitors of Calmodulin-Dependent Kinases That Restore Insulin Sensitivity in the Diet-Induced Obesity in Vivo Mouse Model C Fromont, A Atzori, D Kaur, L Hashmi, G Greco, A Cabanillas, ... Journal of medicinal chemistry 63 (13), 6784-6801, 2020	21	2020
Macrocyclization of quinazoline-based EGFR inhibitors leads to exclusive mutant selectivity for EGFR L858R and Del19 JA Amrhein, TS Beyett, WW Feng, A Krämer, J Weckesser, IK Schaeffner, ... Journal of medicinal chemistry 65 (23), 15679-15697, 2022	19	2022
Selective targeting of the αC and DFG-out pocket in p38 MAPK S Roehm, M Schroeder, JE Dwyer, CS Widdowson, A Chaikuad, ... European Journal of Medicinal Chemistry 208, 112721, 2020	19	2020
Development of a chemical probe against NUDT15 SM Zhang, M Desroses, A Hagenkort, NCK Valerie, D Rehling, M Carter, ... Nature chemical biology 16 (10), 1120-1128, 2020	18	2020
Covalent inhibition of histone deacetylase 8 by 3, 4-dihydro-2H-pyrimido [1, 2-c][1, 3] benzothiazin-6-imine M Muth, N Jänsch, A Kopranovic, A Krämer, N Wössner, M Jung, ... Biochimica et Biophysica Acta (BBA)-General Subjects 1863 (3), 577-585, 2019	18	2019
Illuminating the Dark: Highly Selective Inhibition of Serine/Threonine Kinase 17A with Pyrazolo[1,5-a]pyrimidine-Based Macrocycles CG Kurz, F Preuss, A Tjaden, M Cusack, JA Amrhein, D Chatterjee, ... Journal of Medicinal Chemistry 65 (11), 7799-7817, 2022	16	2022
Leucettinibs, a Class of DYRK/CLK Kinase Inhibitors Inspired by the Marine Sponge Natural Product Leucettamine B E Deau, MF Lindberg, F Miege, D Roche, N George, P George, ... Journal of Medicinal Chemistry 66 (15), 10694-10714, 2023	14	2023
Structure of a glutamine donor mimicking inhibitory peptide shaped by the catalytic cleft of microbial transglutaminase NE Juettner, S Schmelz, A Kraemer, S Knapp, B Becker, H Kolmar, ... The FEBS journal 285 (24), 4684-4694, 2018	14	2018

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