Dependency of a therapy-resistant state of cancer cells on a lipid peroxidase pathway VS Viswanathan, MJ Ryan, HD Dhruv, S Gill, OM Eichhoff, ... Nature 547 (7664), 453-457, 2017 | 1618 | 2017 |
Organoid modeling of the tumor immune microenvironment JT Neal, X Li, J Zhu, V Giangarra, CL Grzeskowiak, J Ju, IH Liu, SH Chiou, ... Cell 175 (7), 1972-1988. e16, 2018 | 1272 | 2018 |
Patient-derived xenografts undergo mouse-specific tumor evolution U Ben-David, G Ha, YY Tseng, NF Greenwald, C Oh, J Shih, ... Nature genetics 49 (11), 1567-1575, 2017 | 774 | 2017 |
PVT1 dependence in cancer with MYC copy-number increase YY Tseng, BS Moriarity, W Gong, R Akiyama, A Tiwari, H Kawakami, ... Nature 512 (7512), 82-86, 2014 | 760 | 2014 |
A GPX4-dependent cancer cell state underlies the clear-cell morphology and confers sensitivity to ferroptosis Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ... Nature communications 10 (1), 1617, 2019 | 704 | 2019 |
Genome-scale activation screen identifies a lncRNA locus regulating a gene neighbourhood J Joung, JM Engreitz, S Konermann, OO Abudayyeh, VK Verdine, F Aguet, ... Nature 548 (7667), 343-346, 2017 | 437 | 2017 |
WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 335 | 2019 |
Assessment of heavy metal bioavailability in contaminated sediments and soils using green fluorescent protein-based bacterial biosensors VHC Liao, MT Chien, YY Tseng, KL Ou Environmental Pollution 142 (1), 17-23, 2006 | 142 | 2006 |
Whole Exome Sequencing Identifies TSC1/TSC2 Biallelic Loss as the Primary and Sufficient Driver Event for Renal Angiomyolipoma Development K Giannikou, IA Malinowska, TJ Pugh, R Yan, YY Tseng, C Oh, J Kim, ... PLoS genetics 12 (8), e1006242, 2016 | 118 | 2016 |
A combination CDK4/6 and IGF1R inhibitor strategy for Ewing sarcoma LM Guenther, NV Dharia, L Ross, A Conway, AL Robichaud, JL Catlett, ... Clinical Cancer Research 25 (4), 1343-1357, 2019 | 87 | 2019 |
The PVT1-MYC duet in cancer YY Tseng, A Bagchi Molecular & Cellular Oncology 2 (2), e974467, 2015 | 82 | 2015 |
CRISPR activation screen identifies BCL-2 proteins and B3GNT2 as drivers of cancer resistance to T cell-mediated cytotoxicity J Joung, PC Kirchgatterer, A Singh, JH Cho, SP Nety, RC Larson, ... Nature Communications 13 (1), 1606, 2022 | 79 | 2022 |
Activation of endothelial cells to pathological status by down-regulation of connexin43 HH Wang, CI Kung, YY Tseng, YC Lin, CH Chen, CH Tsai, HI Yeh Cardiovascular research 79 (3), 509-518, 2008 | 70 | 2008 |
Integrated genetic and pharmacologic interrogation of rare cancers AL Hong, YY Tseng, GS Cowley, O Jonas, JH Cheah, BD Kynnap, ... Nature communications 7 (1), 11987, 2016 | 60 | 2016 |
Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition AL Hong, YY Tseng, JA Wala, WJ Kim, BD Kynnap, MB Doshi, G Kugener, ... Elife 8, e44161, 2019 | 46 | 2019 |
Caenorhabditis elegans expresses a functional ArsA YY Tseng, CW Yu, VHC Liao The FEBS Journal 274 (10), 2566-2572, 2007 | 39 | 2007 |
MYC and PVT1 synergize to regulate RSPO1 levels in breast cancer AL Sarver, CD Murray, NA Temiz, YY Tseng, A Bagchi Cell cycle 15 (7), 881-885, 2016 | 32 | 2016 |
From cell lines to living biosensors: new opportunities to prioritize cancer dependencies using ex vivo tumor cultures YY Tseng, JS Boehm Current Opinion in Genetics & Development 54, 33-40, 2019 | 27 | 2019 |
Systematic profiling of conditional pathway activation identifies context-dependent synthetic lethalities L Chang, NY Jung, A Atari, DJ Rodriguez, D Kesar, TY Song, MG Rees, ... Nature Genetics 55 (10), 1709-1720, 2023 | 20 | 2023 |
HIF-2α drives an intrinsic vulnerability to ferroptosis in clear cell renal cell carcinoma Y Zou, MJ Palte, AA Deik, H Li, JK Eaton, W Wang, YY Tseng, R Deasy, ... BioRxiv, 388041, 2018 | 10 | 2018 |