Amelioration of vascular dysfunctions in diabetic rats by an oral PKC β inhibitor H Ishii, MR Jirousek, D Koya, C Takagi, P Xia, A Clermont, SE Bursell, ... Science 272 (5262), 728-731, 1996 | 1532 | 1996 |
A central role for inflammation in the pathogenesis of diabetic retinopathy AM Joussen, V Poulaki, ML Le, K Koizumi, C Esser, H Janicki, ... The FASEB journal 18 (12), 1450-1452, 2004 | 1460 | 2004 |
Inflammation in diabetic retinopathy J Tang, TS Kern Progress in retinal and eye research 30 (5), 343-358, 2011 | 1235 | 2011 |
Accelerated death of retinal microvascular cells in human and experimental diabetic retinopathy. M Mizutani, TS Kern, M Lorenzi The Journal of clinical investigation 97 (12), 2883-2890, 1996 | 920 | 1996 |
Contributions of inflammatory processes to the development of the early stages of diabetic retinopathy TS Kern Journal of Diabetes Research 2007 (1), 095103, 2007 | 815 | 2007 |
Progression of incipient diabetic retinopathy during good glycemic control RL Engerman, TS Kern Diabetes 36 (7), 808-812, 1987 | 673 | 1987 |
Characterization of the mechanism for the chronic activation of diacylglycerol-protein kinase C pathway in diabetes and hypergalactosemia P Xia, T Inoguchi, TS Kern, RL Engerman, PJ Oates, GL King Diabetes 43 (9), 1122-1129, 1994 | 645 | 1994 |
The Ins2Akita mouse as a model of early retinal complications in diabetes AJ Barber, DA Antonetti, TS Kern, CEN Reiter, RS Soans, JK Krady, ... Investigative ophthalmology & visual science 46 (6), 2210-2218, 2005 | 603 | 2005 |
Abnormalities of retinal metabolism in diabetes and experimental galactosemia: VII. Effect of long-term administration of antioxidants on the development of retinopathy RA Kowluru, J Tang, TS Kern Diabetes 50 (8), 1938-1942, 2001 | 577 | 2001 |
Retinal ganglion cells in diabetes TS Kern, AJ Barber The Journal of physiology 586 (18), 4401-4408, 2008 | 552 | 2008 |
Activation of nuclear factor-κB induced by diabetes and high glucose regulates a proapoptotic program in retinal pericytes G Romeo, WH Liu, V Asnaghi, TS Kern, M Lorenzi Diabetes 51 (7), 2241-2248, 2002 | 528 | 2002 |
Activation of PKC-δ and SHP-1 by hyperglycemia causes vascular cell apoptosis and diabetic retinopathy P Geraldes, J Hiraoka-Yamamoto, M Matsumoto, A Clermont, M Leitges, ... Nature medicine 15 (11), 1298-1306, 2009 | 525 | 2009 |
Hyperglycemia increases mitochondrial superoxide in retina and retinal cells Y Du, CM Miller, TS Kern Free Radical Biology and Medicine 35 (11), 1491-1499, 2003 | 487 | 2003 |
Therapies for hyperglycaemia-induced diabetic complications: from animal models to clinical trials NA Calcutt, ME Cooper, TS Kern, AM Schmidt Nature Reviews Drug Discovery 8 (5), 417-430, 2009 | 475 | 2009 |
Glycation of mitochondrial proteins from diabetic rat kidney is associated with excess superoxide formation MG Rosca, TG Mustata, MT Kinter, AM Ozdemir, TS Kern, LI Szweda, ... American Journal of Physiology-Renal Physiology 289 (2), F420-F430, 2005 | 448 | 2005 |
Experimental galactosemia produces diabetic-like retinopathy RL Engerman, TS Kern Diabetes 33 (1), 97-100, 1984 | 393 | 1984 |
Oxidative damage in the retinal mitochondria of diabetic mice: possible protection by superoxide dismutase M Kanwar, PS Chan, TS Kern, RA Kowluru Investigative ophthalmology & visual science 48 (8), 3805-3811, 2007 | 386 | 2007 |
Pharmacological inhibition of diabetic retinopathy: aminoguanidine and aspirin TS Kern, RL Engerman Diabetes 50 (7), 1636-1642, 2001 | 383 | 2001 |
Photoreceptor cells are major contributors to diabetes-induced oxidative stress and local inflammation in the retina Y Du, A Veenstra, K Palczewski, TS Kern Proceedings of the National Academy of Sciences 110 (41), 16586-16591, 2013 | 349 | 2013 |
Vascular damage in a mouse model of diabetic retinopathy: relation to neuronal and glial changes RA Feit-Leichman, R Kinouchi, M Takeda, Z Fan, S Mohr, TS Kern, ... Investigative ophthalmology & visual science 46 (11), 4281-4287, 2005 | 349 | 2005 |