Morris F White

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C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolE-mailová adresa ověřena na: joslin.harvard.edu
Martin MyersUniversity of MichiganE-mailová adresa ověřena na: umich.edu
Xiao Jian SunThe University of MarylandE-mailová adresa ověřena na: medicine.umaryland.edu
Lynne YenushProfesor Departamento de Biotecnología Universidad Politécnica de ValenciaE-mailová adresa ověřena na: ibmcp.upv.es
Steven ShoelsonHarvard Medical SchoolE-mailová adresa ověřena na: joslin.harvard.edu
Gerald I ShulmanYale School of Medicine/Howard Hughes Medical InstituteE-mailová adresa ověřena na: yale.edu
Sebastian PonsInstituto de Biología Molecular de BarcelonaE-mailová adresa ověřena na: ibmb.csic.es
Zhiyong ChengUniversity of FloridaE-mailová adresa ověřena na: ufl.edu
Shaodong GuoTexas A&M University, College Station, Texas USAE-mailová adresa ověřena na: tamu.edu
Barry J. GoldsteinVice President and Therapeutic Area Head, Covance, IncE-mailová adresa ověřena na: covance.com
Bruce M. SpiegelmanStanley J. Korsmeyer Professor, Harvard Medical School and Dana-Farber Cancer InstituteE-mailová adresa ověřena na: dfci.harvard.edu
Hans-Ulrich HäringProfessor of Endocrinology and DiabetologyE-mailová adresa ověřena na: med.uni-tuebingen.de
Liangyou RuiLouis G. D'Alecy Collegiate Professor of Physiology, University of Michigan Medical SchoolE-mailová adresa ověřena na: umich.edu
X. Charlie DongIndiana University School of MedicineE-mailová adresa ověřena na: iu.edu
Marianna SadagurskiWayne State UniversityE-mailová adresa ověřena na: wayne.edu
John BlenisProfessor of Pharmacology, Weill Cornell MedicineE-mailová adresa ověřena na: med.cornell.edu
Stephen PrevisMerckE-mailová adresa ověřena na: merck.com
Joseph SchlessingerYale university School of MedicineE-mailová adresa ověřena na: Yale.edu
Susan Bonner-Weir , Susan Bonner W...Joslin Diabetes Center, Harvard Medical SchoolE-mailová adresa ověřena na: joslin.harvard.edu
Sunmin ParkHoseo UniversityE-mailová adresa ověřena na: hoseo.edu

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Morris F White

Professor of Pediatrics, Harvard Medical School

E-mailová adresa ověřena na: childrens.harvard.edu - Domovská stránka

insulin action insulin diabetes


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
IRS-1-mediated inhibition of insulin receptor tyrosine kinase activity in TNF-α-and obesity-induced insulin resistance GS Hotamisligil, P Peraldi, A Budavari, R Ellis, MF White, BM Spiegelman Science 271 (5249), 665-670, 1996	3725	1996
Disruption of IRS-2 causes type 2 diabetes in mice DJ Withers, JS Gutierrez, H Towery, DJ Burks, JM Ren, S Previs, Y Zhang, ... Nature 391 (6670), 900-904, 1998	2177	1998
The insulin signaling system. MF White, CR Kahn Journal of Biological Chemistry 269 (1), 1-4, 1994	2121	1994
Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein XJ Sun, P Rothenberg, CR Kahn, JM Backer, E Araki, PA Wilden, ... Nature 352 (6330), 73-77, 1991	2073	1991
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle C Yu, Y Chen, GW Cline, D Zhang, H Zong, Y Wang, R Bergeron, JK Kim, ... Journal of Biological Chemistry 277 (52), 50230-50236, 2002	1984	2002
The c-Jun NH2-terminal kinase promotes insulin resistance during association with insulin receptor substrate-1 and phosphorylation of Ser307 V Aguirre, T Uchida, L Yenush, R Davis, MF White Journal of Biological Chemistry 275 (12), 9047-9054, 2000	1984	2000
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. ME Griffin, MJ Marcucci, GW Cline, K Bell, N Barucci, D Lee, LJ Goodyear, ... Diabetes 48 (6), 1270-1274, 1999	1736	1999
IRS proteins and the common path to diabetes MF White American Journal of Physiology-Endocrinology and Metabolism 283 (3), E413-E422, 2002	1342	2002
Phosphorylation of Ser307 in insulin receptor substrate-1 blocks interactions with the insulin receptor and inhibits insulin action V Aguirre, ED Werner, J Giraud, YH Lee, SE Shoelson, MF White Journal of Biological Chemistry 277 (2), 1531-1537, 2002	1308	2002
SOCS-1 and SOCS-3 block insulin signaling by ubiquitin-mediated degradation of IRS1 and IRS2 L Rui, M Yuan, D Frantz, S Shoelson, MF White Journal of Biological Chemistry 277 (44), 42394-42398, 2002	1215	2002
Regulation of insulin sensitivity by serine/threonine phosphorylation of insulin receptor substrate proteins IRS1 and IRS2 KD Copps, MF White Diabetologia 55, 2565-2582, 2012	1191	2012
Role of IRS-2 in insulin and cytokine signalling XJ Sun, LM Wang, Y Zhang, L Yenush, MG Myers Jr, E Glasheen, ... Nature 377 (6545), 173-177, 1995	1176	1995
Reduced mitochondrial density and increased IRS-1 serine phosphorylation in muscle of insulin-resistant offspring of type 2 diabetic parents K Morino, KF Petersen, S Dufour, D Befroy, J Frattini, N Shatzkes, ... The Journal of clinical investigation 115 (12), 3587-3593, 2005	1055	2005
The IRS-signalling system: a network of docking proteins that mediate insulin action MF White Insulin Action, 3-11, 1998	1017	1998
Insulin signaling in health and disease MF White Science 302 (5651), 1710-1711, 2003	960	2003
Insulin rapidly stimulates tyrosine phosphorylation of a M_r-185,000 protein in intact cells MF White, R Maron, CR Kahn Nature 318 (6042), 183-186, 1985	874	1985
The SH2/SH3 domain‐containing protein GRB2 interacts with tyrosine‐phosphorylated IRS1 and Shc: implications for insulin control of ras signalling. EY Skolnik, CH Lee, A Batzer, LM Vicentini, M Zhou, R Daly, MJ Myers Jr, ... The EMBO journal 12 (5), 1929-1936, 1993	872	1993
The insulin signalling system and the IRS proteins MF White Diabetologia 40, S2-S17, 1997	808	1997
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats ZY Jiang, YW Lin, A Clemont, EP Feener, KD Hein, M Igarashi, ... The Journal of clinical investigation 104 (4), 447-457, 1999	803	1999
Common elements in growth factor stimulation and oncogenic transformation: 85 kd phosphoprotein and phosphatidylinositol kinase activity DR Kaplan, M Whitman, B Schaffhausen, DC Pallas, M White, L Cantley, ... Cell 50 (7), 1021-1029, 1987	795	1987

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