| Antifreeze protein from freeze-tolerant grass has a beta-roll fold with an irregularly structured ice-binding site AJ Middleton, CB Marshall, F Faucher, M Bar-Dolev, I Braslavsky, ... Journal of molecular biology 416 (5), 713-724, 2012 | 163 | 2012 |
| Ice restructuring inhibition activities in antifreeze proteins with distinct differences in thermal hysteresis OY Sally, A Brown, AJ Middleton, MM Tomczak, VK Walker, PL Davies Cryobiology 61 (3), 327-334, 2010 | 128 | 2010 |
| Identification of the ice-binding face of a plant antifreeze protein AJ Middleton, AM Brown, PL Davies, VK Walker FEBS letters 583 (4), 815-819, 2009 | 112 | 2009 |
| Compound ice-binding site of an antifreeze protein revealed by mutagenesis and fluorescent tagging CP Garnham, A Natarajan, AJ Middleton, MJ Kuiper, I Braslavsky, ... Biochemistry 49 (42), 9063-9071, 2010 | 109 | 2010 |
| Expression and characterization of an antifreeze protein from the perennial rye grass, Lolium perenne KJ Lauersen, A Brown, A Middleton, PL Davies, VK Walker Cryobiology 62 (3), 194-201, 2011 | 65 | 2011 |
| The molecular basis of lysine 48 ubiquitin chain synthesis by Ube2K AJ Middleton, CL Day Scientific reports 5 (1), 16793, 2015 | 63 | 2015 |
| The activity of TRAF RING homo-and heterodimers is regulated by zinc finger 1 AJ Middleton, R Budhidarmo, A Das, J Zhu, M Foglizzo, PD Mace, CL Day Nature communications 8 (1), 1788, 2017 | 45 | 2017 |
| A bidentate Polycomb Repressive-Deubiquitinase complex is required for efficient activity on nucleosomes M Foglizzo, AJ Middleton, AE Burgess, JM Crowther, RCJ Dobson, ... Nature communications 9 (1), 3932, 2018 | 39 | 2018 |
| Structure and function of the RING domains of RNF20 and RNF40, dimeric E3 ligases that monoubiquitylate histone H2B M Foglizzo, AJ Middleton, CL Day Journal of molecular biology 428 (20), 4073-4086, 2016 | 34 | 2016 |
| Regulation of E2s: a role for additional ubiquitin binding sites? AJ Middleton, JD Wright, CL Day Journal of molecular biology 429 (22), 3430-3440, 2017 | 27 | 2017 |
| Use of E2~ ubiquitin conjugates for the characterization of ubiquitin transfer by RING E3 ligases such as the inhibitor of apoptosis proteins AJ Middleton, R Budhidarmo, CL Day Methods in Enzymology 545, 243-263, 2014 | 26 | 2014 |
| The structure and ubiquitin binding properties of TRAF RING heterodimers A Das, AJ Middleton, P Padala, EC Ledgerwood, PD Mace, CL Day Journal of Molecular Biology 433 (8), 166844, 2021 | 23 | 2021 |
| The RING domain of RING finger 12 efficiently builds degradative ubiquitin chains AJ Middleton, J Zhu, CL Day Journal of molecular biology 432 (13), 3790-3801, 2020 | 22 | 2020 |
| Identification of ubiquitin variants that inhibit the E2 ubiquitin conjugating enzyme, Ube2k AJ Middleton, J Teyra, J Zhu, SS Sidhu, CL Day ACS chemical biology 16 (9), 1745-1756, 2021 | 19 | 2021 |
| Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C A Paluda, AJ Middleton, C Rossig, PD Mace, CL Day Nature Communications 13 (1), 1181, 2022 | 17 | 2022 |
| Isolation and characterization of ice-binding proteins from higher plants AJ Middleton, B Vanderbeld, M Bredow, H Tomalty, PL Davies, VK Walker Plant Cold Acclimation: Methods and Protocols, 255-277, 2014 | 14 | 2014 |
| The RING domain of RING Finger 11 (RNF 11) protein binds Ubc13 and inhibits formation of polyubiquitin chains R Budhidarmo, J Zhu, AJ Middleton, CL Day FEBS letters 592 (8), 1434-1444, 2018 | 12 | 2018 |
| From seeds to trees: how E2 enzymes grow ubiquitin chains AJ Middleton, CL Day Biochemical Society Transactions 51 (1), 353-362, 2023 | 8 | 2023 |
| Genetically-engineered mutant antifreeze proteins provide insight into hydrate inhibition D Myran, A Middleton, J Choi, R Gordienko, H Ohno, JA Ripmeester, ... Proceedings of the 7th International Conference on Gas Hydrates, 17-21, 2011 | 8 | 2011 |
| Structural insights into K48-linked ubiquitin chain formation by the Pex4p-Pex22p complex MR Groves, CFE Schroer, AJ Middleton, S Lunev, N Danda, AM Ali, ... Biochemical and biophysical research communications 496 (2), 562-567, 2018 | 6 | 2018 |
