Identification of required host factors for SARS-CoV-2 infection in human cells Z Daniloski, TX Jordan, HH Wessels, DA Hoagland, S Kasela, M Legut, ... Cell 184 (1), 92-105. e16, 2021 | 569 | 2021 |
Regnase-1 and roquin regulate a common element in inflammatory mRNAs by spatiotemporally distinct mechanisms T Mino, Y Murakawa, A Fukao, A Vandenbon, HH Wessels, D Ori, ... Cell 161 (5), 1058-1073, 2015 | 390 | 2015 |
Massively parallel Cas13 screens reveal principles for guide RNA design HH Wessels, A Méndez-Mancilla, X Guo, M Legut, Z Daniloski, ... Nature biotechnology 38 (6), 722-727, 2020 | 360 | 2020 |
Purification of cross-linked RNA-protein complexes by phenol-toluol extraction EC Urdaneta, CH Vieira-Vieira, T Hick, HH Wessels, D Figini, R Moschall, ... Nature communications 10 (1), 990, 2019 | 221 | 2019 |
Argonaute2 mediates compensatory expansion of the pancreatic β cell SG Tattikota, T Rathjen, SJ McAnulty, HH Wessels, I Akerman, ... Cell metabolism 19 (1), 122-134, 2014 | 174 | 2014 |
Characterizing the molecular regulation of inhibitory immune checkpoints with multimodal single-cell screens E Papalexi, EP Mimitou, AW Butler, S Foster, B Bracken, WM Mauck III, ... Nature genetics 53 (3), 322-331, 2021 | 155 | 2021 |
The mRNA-bound proteome of the early fly embryo HH Wessels, K Imami, AG Baltz, M Kolinski, A Beldovskaya, M Selbach, ... Genome research 26 (7), 1000-1009, 2016 | 89 | 2016 |
Profiling the genetic determinants of chromatin accessibility with scalable single-cell CRISPR screens N Liscovitch-Brauer, A Montalbano, J Deng, A Méndez-Mancilla, ... Nature biotechnology 39 (10), 1270-1277, 2021 | 87 | 2021 |
Ythdf is a N6‐methyladenosine reader that modulates Fmr1 target mRNA selection and restricts axonal growth in Drosophila L Worpenberg, C Paolantoni, S Longhi, MM Mulorz, T Lence, HH Wessels, ... The EMBO journal 40 (4), e104975, 2021 | 80 | 2021 |
Deciphering human ribonucleoprotein regulatory networks N Mukherjee, HH Wessels, S Lebedeva, M Sajek, M Ghanbari, A Garzia, ... Nucleic acids research 47 (2), 570-581, 2019 | 68 | 2019 |
Transcriptome-wide Cas13 guide RNA design for model organisms and viral RNA pathogens X Guo, JA Rahman, HH Wessels, A Méndez-Mancilla, D Haro, X Chen, ... Cell Genomics 1 (1), 2021 | 67 | 2021 |
miR-184 regulates pancreatic β-cell function according to glucose metabolism SG Tattikota, T Rathjen, J Hausser, A Khedkar, UD Kabra, V Pandey, ... Journal of Biological Chemistry 290 (33), 20284-20294, 2015 | 66 | 2015 |
High-throughput screens of PAM-flexible Cas9 variants for gene knockout and transcriptional modulation M Legut, Z Daniloski, X Xue, D McKenzie, X Guo, HH Wessels, ... Cell reports 30 (9), 2859-2868. e5, 2020 | 64 | 2020 |
Argonaute2 regulates the pancreatic β-cell secretome SG Tattikota, MD Sury, T Rathjen, HH Wessels, AK Pandey, X You, ... Molecular & Cellular Proteomics 12 (5), 1214-1225, 2013 | 58 | 2013 |
Prediction of on-target and off-target activity of CRISPR–Cas13d guide RNAs using deep learning HH Wessels, A Stirn, A Méndez-Mancilla, EJ Kim, SK Hart, DA Knowles, ... Nature biotechnology 42 (4), 628-637, 2024 | 55 | 2024 |
Global identification of functional microRNA-mRNA interactions in Drosophila HH Wessels, S Lebedeva, A Hirsekorn, R Wurmus, A Akalin, N Mukherjee, ... Nature communications 10 (1), 1626, 2019 | 54 | 2019 |
Efficient combinatorial targeting of RNA transcripts in single cells with Cas13 RNA Perturb-seq HH Wessels, A Méndez-Mancilla, Y Hao, E Papalexi, WM Mauck III, L Lu, ... Nature methods 20 (1), 86-94, 2023 | 51 | 2023 |
Chemically modified guide RNAs enhance CRISPR-Cas13 knockdown in human cells A Méndez-Mancilla, HH Wessels, M Legut, A Kadina, M Mabuchi, ... Cell chemical biology 29 (2), 321-327. e4, 2022 | 46 | 2022 |
omniCLIP: probabilistic identification of protein-RNA interactions from CLIP-seq data P Drewe-Boss, HH Wessels, U Ohler Genome biology 19, 1-14, 2018 | 32 | 2018 |
Faithful heteroscedastic regression with neural networks A Stirn, H Wessels, M Schertzer, L Pereira, N Sanjana, D Knowles International Conference on Artificial Intelligence and Statistics, 5593-5613, 2023 | 23 | 2023 |