Sticky fingers: zinc-fingers as protein-recognition motifs R Gamsjaeger, CK Liew, FE Loughlin, M Crossley, JP Mackay Trends in biochemical sciences 32 (2), 63-70, 2007 | 554 | 2007 |
C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu (I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu (I … Z Xiao, F Loughlin, GN George, GJ Howlett, AG Wedd Journal of the American Chemical Society 126 (10), 3081-3090, 2004 | 294 | 2004 |
The solution structure of FUS bound to RNA reveals a bipartite mode of RNA recognition with both sequence and shape specificity FE Loughlin, PJ Lukavsky, T Kazeeva, S Reber, EM Hock, M Colombo, ... Molecular cell 73 (3), 490-504. e6, 2019 | 195 | 2019 |
Structural basis of pre-let-7 miRNA recognition by the zinc knuckles of pluripotency factor Lin28 FE Loughlin, LFR Gebert, H Towbin, A Brunschweiger, J Hall, FHT Allain Nature structural & molecular biology 19 (1), 84-89, 2012 | 173 | 2012 |
Crystal structures of flax rust avirulence proteins AvrL567-A and-D reveal details of the structural basis for flax disease resistance specificity CIA Wang, G Guncˇar, JK Forwood, T Teh, AM Catanzariti, GJ Lawrence, ... The Plant Cell 19 (9), 2898-2912, 2007 | 169 | 2007 |
Zinc fingers as protein recognition motifs: structural basis for the GATA-1/friend of GATA interaction CK Liew, RJY Simpson, AHY Kwan, LA Crofts, FE Loughlin, JM Matthews, ... Proceedings of the National Academy of Sciences 102 (3), 583-588, 2005 | 123 | 2005 |
Characterization of a family of RanBP2-type zinc fingers that can recognize single-stranded RNA CD Nguyen, RE Mansfield, W Leung, PM Vaz, FE Loughlin, RP Grant, ... Journal of molecular biology 407 (2), 273-283, 2011 | 122 | 2011 |
The zinc fingers of the SR-like protein ZRANB2 are single-stranded RNA-binding domains that recognize 5′ splice site-like sequences FE Loughlin, RE Mansfield, PM Vaz, AP McGrath, S Setiyaputra, ... Proceedings of the National Academy of Sciences 106 (14), 5581-5586, 2009 | 115 | 2009 |
Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis D Jutzi, S Campagne, R Schmidt, S Reber, J Mechtersheimer, F Gypas, ... Nature Communications 11 (1), 6341, 2020 | 69 | 2020 |
TDP-43 and FUS–structural insights into RNA recognition and self-association FE Loughlin, JA Wilce Current opinion in structural biology 59, 134-142, 2019 | 53 | 2019 |
A rapid method for assessing the RNA-binding potential of a protein K Bendak, FE Loughlin, V Cheung, MR O’Connell, M Crossley, ... Nucleic acids research 40 (14), e105-e105, 2012 | 46 | 2012 |
Analysis of the Structure and Function of the Transcriptional Coregulator HOP, H Kook, WW Yung, RJ Simpson, HJ Kee, S Shin, JA Lowry, FE Loughlin, ... Biochemistry 45 (35), 10584-10590, 2006 | 45 | 2006 |
Designed metal-binding sites in biomolecular and bioinorganic interactions JM Matthews, FE Loughlin, JP Mackay Current opinion in structural biology 18 (4), 484-490, 2008 | 38 | 2008 |
Tandem RNA binding sites induce self-association of the stress granule marker protein TIA-1 FE Loughlin, DL West, MJ Gunzburg, S Waris, SA Crawford, MCJ Wilce, ... Nucleic acids research 49 (5), 2403-2417, 2021 | 34 | 2021 |
TIA-1 RRM23 binding and recognition of target oligonucleotides S Waris, SM García-Mauriño, A Sivakumaran, SA Beckham, FE Loughlin, ... Nucleic Acids Research 45 (8), 4944-4957, 2017 | 22 | 2017 |
The NMR signature of gluconoylation: a frequent N-terminal modification of isotope-labeled proteins D Schweida, P Barraud, C Regl, FE Loughlin, CG Huber, C Cabrele, ... Journal of biomolecular NMR 73, 71-79, 2019 | 14 | 2019 |
The solution structure of Dead End bound to AU-rich RNA reveals an unprecedented mode of tandem RRM-RNA recognition required for mRNA regulation MM Duszczyk, H Wischnewski, T Kazeeva, FE Loughlin, C von Schroetter, ... BioRxiv, 572156, 2019 | 10 | 2019 |
The solution structure of Dead End bound to AU-rich RNA reveals an unusual mode of tandem RRM-RNA recognition required for mRNA regulation MM Duszczyk, H Wischnewski, T Kazeeva, R Arora, FE Loughlin, ... Nature communications 13 (1), 5892, 2022 | 9 | 2022 |
Crystallization of a ZRANB2–RNA complex FE Loughlin, M Lee, JM Guss, JP Mackay Structural Biology and Crystallization Communications 64 (12), 1175-1177, 2008 | 8 | 2008 |
Zinc fingers are known as domains for binding DNA and RNA. Do they also mediate protein-protein interactions? FE Loughlin, JP Mackay IUBMB life 58 (12), 2006 | 8 | 2006 |