Dudley Lamming

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David M. SabatiniInstitute of Organic Chemistry and Biochemistry of the CASE-mailová adresa ověřena na: uochb.cas.cz
Cara GreenPostdoc Researcher, University of Wisconsin-MadisonE-mailová adresa ověřena na: wisc.edu
David A. SinclairHarvard Medical School (Genetics)E-mailová adresa ověřena na: hms.harvard.edu
Joseph A. BaurProfessor of Physiology, University of PennsylvaniaE-mailová adresa ověřena na: mail.med.upenn.edu
Deyang YuUniversity of Wisconsin-MadisonE-mailová adresa ověřena na: wisc.edu
Sebastian I Arriola Apelo, Ph.D.Assistant Professor of Metabolism, Department of Animal & Dairy Sciences, University of WisconsinE-mailová adresa ověřena na: wisc.edu
Michelle KimpleAssistant Professor of Medicine, University of Wisconsin-MadisonE-mailová adresa ověřena na: medicine.wisc.edu
Nicole RichardsonPostdoctoral Fellow, University of WashingtonE-mailová adresa ověřena na: uw.edu
Shany E. YangPh.D. Candidate, University of MichiganE-mailová adresa ověřena na: umich.edu
Jacqueline A BrinkmanGraduate student at University of North Carolina at Chapel HillE-mailová adresa ověřena na: email.unc.edu
Luigi Fontana MD PhD FRACPUniversity of SydneyE-mailová adresa ověřena na: sydney.edu.au
John M DenuWisconsin Institute for Discovery, Professor of Biomolecular Chemistry,University of Wisconsin-MadisonE-mailová adresa ověřena na: wisc.edu
Ildiko KaszaSenior ScientistE-mailová adresa ověřena na: promega.com
Jason WoodBrown UniversityE-mailová adresa ověřena na: brown.edu
Pekka KatajistoUniversity of Helsinki and Karolinska InstitutetE-mailová adresa ověřena na: helsinki.fi
Matthew J. Merrins, PhDAssociate Professor, University of Wisconsin-MadisonE-mailová adresa ověřena na: wisc.edu
Sabrina DumasUniversity of Wisconsin-MadisonE-mailová adresa ověřena na: wisc.edu
Rafael De CaboTranslational Gerontology Branch, National Institute on AgingE-mailová adresa ověřena na: grc.nia.nih.gov
Faizan SyedE-mailová adresa ověřena na: uwalumni.com
Haim CohenBiology professorE-mailová adresa ověřena na: biu.ac.il

Sledovat

Dudley Lamming

Associate Professor of Medicine, University of Wisconsin-Madison

E-mailová adresa ověřena na: medicine.wisc.edu - Domovská stránka

Biology of Aging mTOR rapamycin branched-chain amino acids diabetes


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan KT Howitz, KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, ... Nature 425 (6954), 191-196, 2003	4939	2003
Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ... Science 335 (6076), 1638, 2012	1377	2012
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ... Cell 130 (6), 1095-1107, 2007	1140	2007
High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016	821	2016
mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ... Nature 486 (7404), 490-495, 2012	812	2012
TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO S Robida-Stubbs, K Glover-Cutter, DW Lamming, M Mizunuma, ... Cell metabolism 15 (5), 713-724, 2012	764	2012
Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ... Science 339 (6124), 1216-1219, 2013	670	2013
The TSC-mTOR pathway regulates macrophage polarization V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ... Nature communications 4 (1), 2834, 2013	626	2013
Rapalogs and mTOR inhibitors as anti-aging therapeutics DW Lamming, L Ye, DM Sabatini, JA Baur The Journal of clinical investigation 123 (3), 980-989, 2013	614	2013
The mechanistic target of rapamycin: the grand conducTOR of metabolism and aging BK Kennedy, DW Lamming Cell metabolism 23 (6), 990-1003, 2016	554	2016
Molecular mechanisms of dietary restriction promoting health and longevity CL Green, DW Lamming, L Fontana Nature Reviews Molecular Cell Biology 23 (1), 56-73, 2022	509	2022
Decreased consumption of branched-chain amino acids improves metabolic health L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ... Cell reports 16 (2), 520-530, 2016	459	2016
A central role for mTOR in lipid homeostasis DW Lamming, DM Sabatini Cell metabolism 18 (4), 465-469, 2013	420	2013
Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ... elife 5, e11612, 2016	414	2016
MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae O Medvedik, DW Lamming, KD Kim, DA Sinclair PLoS biology 5 (10), e261, 2007	394	2007
Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer R Strong, RA Miller, A Antebi, CM Astle, M Bogue, MS Denzel, ... Aging cell 15 (5), 872-884, 2016	349	2016
STING senses microbial viability to orchestrate stress-mediated autophagy of the endoplasmic reticulum J Moretti, S Roy, D Bozec, J Martinez, JR Chapman, B Ueberheide, ... Cell 171 (4), 809-823. e13, 2017	333	2017
Restoration of metabolic health by decreased consumption of branched‐chain amino acids NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ... The Journal of physiology 596 (4), 623-645, 2018	331	2018
Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile EM Mercken, SD Crosby, DW Lamming, L JeBailey, S Krzysik‐Walker, ... Aging cell 12 (4), 645-651, 2013	302	2013
The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine D Yu, NE Richardson, CL Green, AB Spicer, ME Murphy, V Flores, C Jang, ... Cell metabolism 33 (5), 905-922. e6, 2021	298	2021

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