Dopaminylation of histone H3 in ventral tegmental area regulates cocaine seeking AE Lepack, CT Werner, AF Stewart, SL Fulton, P Zhong, LA Farrelly, ... Science 368 (6487), 197-201, 2020 | 216 | 2020 |
Little things on which happiness depends: microRNAs as novel therapeutic targets for the treatment of anxiety and depression RM O'connor, TG Dinan, JF Cryan Molecular psychiatry 17 (4), 359-376, 2012 | 169 | 2012 |
microRNAs as novel antidepressant targets: converging effects of ketamine and electroconvulsive shock therapy in the rat hippocampus RM O'Connor, S Grenham, TG Dinan, JF Cryan International Journal of Neuropsychopharmacology 16 (8), 1885-1892, 2013 | 145 | 2013 |
MicroRNAs as biomarkers for major depression: a role for let-7b and let-7c A Gururajan, ME Naughton, KA Scott, RM O'connor, G Moloney, G Clarke, ... Translational psychiatry 6 (8), e862-e862, 2016 | 137 | 2016 |
Genetic strain differences in learned fear inhibition associated with variation in neuroendocrine, autonomic, and amygdala dendritic phenotypes MC Camp, KP MacPherson, L Lederle, C Graybeal, S Gaburro, ... Neuropsychopharmacology 37 (6), 1534-1547, 2012 | 111 | 2012 |
Habenular TCF7L2 links nicotine addiction to diabetes A Duncan, MP Heyer, M Ishikawa, SPB Caligiuri, X Liu, Z Chen, ... Nature 574 (7778), 372-377, 2019 | 106 | 2019 |
Metabotropic glutamate receptor 7: at the interface of cognition and emotion RM O'Connor, BC Finger, PJ Flor, JF Cryan European Journal of Pharmacology 639 (1-3), 123-131, 2010 | 104 | 2010 |
Riluzole normalizes early-life stress-induced visceral hypersensitivity in rats: role of spinal glutamate reuptake mechanisms RD Gosselin, RM O'Connor, M Tramullas, M Julio–Pieper, TG Dinan, ... Gastroenterology 138 (7), 2418-2425, 2010 | 104 | 2010 |
Lithium-induced effects on adult hippocampal neurogenesis are topographically segregated along the dorso-ventral axis of stressed mice OF O’Leary, RM O’Connor, JF Cryan Neuropharmacology 62 (1), 247-255, 2012 | 74 | 2012 |
All roads lead to the miRNome: miRNAs have a central role in the molecular pathophysiology of psychiatric disorders RM O’Connor, A Gururajan, TG Dinan, PJ Kenny, JF Cryan Trends in pharmacological sciences 37 (12), 1029-1044, 2016 | 72 | 2016 |
P-glycoprotein inhibition increases the brain distribution and antidepressant-like activity of escitalopram in rodents FE O'brien, RM O'connor, G Clarke, TG Dinan, BT Griffin, JF Cryan Neuropsychopharmacology 38 (11), 2209-2219, 2013 | 58 | 2013 |
Regulation of the brain–gut axis by group III metabotropic glutamate receptors M Julio-Pieper, RM O’Connor, TG Dinan, JF Cryan European Journal of Pharmacology 698 (1-3), 19-30, 2013 | 52 | 2013 |
Metabotropic glutamate receptors in central nervous system diseases A V Golubeva, R D Moloney, R M O'Connor, T G Dinan, J F Cryan Current drug targets 17 (5), 538-616, 2016 | 45 | 2016 |
Adolescent brain vulnerability and psychopathology through the generations: role of diet and dopamine RM O’Connor, JF Cryan Biological Psychiatry 75 (1), 4-6, 2014 | 43 | 2014 |
Impact of early-life stress, on group III mGlu receptor levels in the rat hippocampus: effects of ketamine, electroconvulsive shock therapy and fluoxetine treatment RM O'Connor, MM Pusceddu, TG Dinan, JF Cryan Neuropharmacology 66, 236-241, 2013 | 42 | 2013 |
Enhancing glutamatergic transmission during adolescence reverses early-life stress-induced deficits in the rewarding effects of cocaine in rats RM O'Connor, RD Moloney, J Glennon, S Vlachou, JF Cryan Neuropharmacology 99, 168-176, 2015 | 37 | 2015 |
Adult siRNA-induced knockdown of mGlu7 receptors reduces anxiety in the mouse RM O'Connor, DR Thakker, M Schmutz, H van der Putten, D Hoyer, ... Neuropharmacology 72, 66-73, 2013 | 35 | 2013 |
The effects of mGlu7 receptor modulation in behavioural models sensitive to antidepressant action in two mouse strains RM O’Connor, JF Cryan Behavioural pharmacology 24 (2), 105-113, 2013 | 30 | 2013 |
Opposing roles for striatonigral and striatopallidal neurons in dorsolateral striatum in consolidating new instrumental actions ACW Smith, S Jonkman, AG Difeliceantonio, RM O’Connor, S Ghoshal, ... Nature communications 12 (1), 5121, 2021 | 29 | 2021 |
Drugs, genes and the blues: pharmacogenetics of the antidepressant response from mouse to man OF O'Leary, FE O'Brien, RM O'Connor, JF Cryan Pharmacology Biochemistry and Behavior 123, 55-76, 2014 | 23 | 2014 |