Sledovat
Paavo Honkakoski
Paavo Honkakoski
University of Eastern Finland, School of Pharmacy
E-mailová adresa ověřena na: uef.fi - Domovská stránka
Název
Citace
Citace
Rok
The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the CYP2B Gene
P Honkakoski, I Zelko, T Sueyoshi, M Negishi
Molecular and cellular biology 18 (10), 5652-5658, 1998
9011998
The repressed nuclear receptor CAR responds to phenobarbital in activating the human CYP2B6 gene
T Sueyoshi, T Kawamoto, I Zelko, P Honkakoski, M Negishi
Journal of Biological Chemistry 274 (10), 6043-6046, 1999
8411999
Inhibition and induction of human cytochrome P450 enzymes: current status
O Pelkonen, M Turpeinen, J Hakkola, P Honkakoski, J Hukkanen, ...
Archives of toxicology 82, 667-715, 2008
7292008
Regulation of cytochrome P450 (CYP) genes by nuclear receptors
P Honkakoski, M Negishi
Biochemical Journal 347 (2), 321-337, 2000
6652000
Extracellular glycosaminoglycans modify cellular trafficking of lipoplexes and polyplexes
M Ruponen, S Rönkkö, P Honkakoski, J Pelkonen, M Tammi, A Urtti
Journal of Biological Chemistry 276 (36), 33875-33880, 2001
2662001
Drug-activated nuclear receptors CAR and PXR
P Honkakoski, T Sueyoshi, M Negishi
Annals of medicine 35 (3), 172-182, 2003
2322003
Extracellular and intracellular barriers in non-viral gene delivery
M Ruponen, P Honkakoski, S Rönkkö, J Pelkonen, M Tammi, A Urtti
Journal of controlled release 93 (2), 213-217, 2003
2222003
Activation by diverse xenochemicals of the 51-base pair phenobarbital-responsive enhancer module in the CYP2B10Gene
P Honkakoski, R Moore, KA Washburn, M Negishi
Molecular pharmacology 53 (4), 597-601, 1998
2191998
Characterization of a phenobarbital-responsive enhancer module in mouse P450 Cyp2b10 gene
P Honkakoski, M Negishi
Journal of Biological Chemistry 272 (23), 14943-14949, 1997
2111997
High variability of nitrosamine metabolism among individuals: Role of cytochromes P450 2A6 and 2E1 in the dealkylation of N‐nitrosodimethylamine and N‐nitrosodiethylamine in …
AM Camus, O Geneste, P Honkakoski, JC Béréziat, CJ Henderson, ...
Molecular carcinogenesis 7 (4), 268-275, 1993
1861993
Substrates and inhibitors of efflux proteins interfere with the MTT assay in cells and may lead to underestimation of drug toxicity
KS Vellonen, P Honkakoski, A Urtti
European journal of pharmaceutical sciences 23 (2), 181-188, 2004
1632004
Immunochemical and catalytical studies on hepatic coumarin 7-hydroxylase in man, rat, and mouse
H Raunio, T Syngelmä, M Pasanen, R Juvonen, P Honkakoski, ...
Biochemical pharmacology 37 (20), 3889-3895, 1988
1471988
Cell‐surface glycosaminoglycans inhibit cation‐mediated gene transfer
M Ruponen, P Honkakoski, M Tammi, A Urtti
The Journal of Gene Medicine: A cross‐disciplinary journal for research on …, 2004
1422004
Characterization of phenobarbital-inducible mouse Cyp2b10 gene transcription in primary hepatocytes
P Honkakoski, R Moore, J Gynther, M Negishi
Journal of Biological Chemistry 271 (16), 9746-9753, 1996
1371996
Mouse steroid 15. alpha.-hydroxylase gene family: identification of type II P-45015. alpha. as coumarin 7-hydroxylase
M Negishi, R Lindberg, B Burkhart, T Ichikawa, P Honkakoski, M Lang
Biochemistry 28 (10), 4169-4172, 1989
1281989
Protein serine/threonine phosphatase inhibitors suppress phenobarbital-induced Cyp2b10 gene transcription in mouse primary hepatocytes
P HONKAKOSKI, M NEGISHI
Biochemical Journal 330 (2), 889-895, 1998
1261998
Peptide− oligonucleotide phosphorothioate conjugates with membrane translocation and nuclear localization properties
M Antopolsky, E Azhayeva, U Tengvall, S Auriola, I Jääskeläinen, ...
Bioconjugate chemistry 10 (4), 598-606, 1999
1231999
Cocaine N-demethylation and the metabolism-related hepatotoxicity can be prevented by cytochrome P450 3A inhibitors
P Pellinen, P Honkakoski, F Stenbäck, M Niemitz, E Alhava, O Pelkonen, ...
European Journal of Pharmacology: Environmental Toxicology and Pharmacology …, 1994
1181994
Towards personalized medicine with a three-dimensional micro-scale perfusion-based two-chamber tissue model system
L Ma, J Barker, C Zhou, W Li, J Zhang, B Lin, G Foltz, J Küblbeck, ...
Biomaterials 33 (17), 4353-4361, 2012
1102012
Characterization of human cytochrome P450 induction by pesticides
K Abass, V Lämsä, P Reponen, J Küblbeck, P Honkakoski, S Mattila, ...
Toxicology 294 (1), 17-26, 2012
1102012
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Články 1–20