A multifunctional Pasteurella multocida sialyltransferase: a powerful tool for the synthesis of sialoside libraries H Yu, H Chokhawala, R Karpel, H Yu, B Wu, J Zhang, Y Zhang, Q Jia, ... Journal of the American Chemical Society 127 (50), 17618-17619, 2005 | 385 | 2005 |
Diversity in specificity, abundance, and composition of anti-Neu5Gc antibodies in normal humans: potential implications for disease V Padler-Karavani, H Yu, H Cao, H Chokhawala, F Karp, N Varki, X Chen, ... Glycobiology 18 (10), 818-830, 2008 | 378 | 2008 |
Differential high-affinity interaction of dectin-1 with natural or synthetic glucans is dependent upon primary structure and is influenced by polymer chain length and side … EL Adams, PJ Rice, B Graves, HE Ensley, H Yu, GD Brown, S Gordon, ... Journal of Pharmacology and Experimental Therapeutics 325 (1), 115-123, 2008 | 364 | 2008 |
MicroRNA-494 is required for the accumulation and functions of tumor-expanded myeloid-derived suppressor cells via targeting of PTEN Y Liu, L Lai, Q Chen, Y Song, S Xu, F Ma, X Wang, J Wang, H Yu, X Cao, ... The Journal of Immunology 188 (11), 5500-5510, 2012 | 295 | 2012 |
Highly Efficient Chemoenzymatic Synthesis of Naturally Occurring and Unnatural α2, 6-Linked Sialosides: A P. damsela α2, 6-Sialyltransferase with Extremely Flexible Donor … H Yu, S Huang, H Chokhawala, M Sun, H Zheng, X Chen Angewandte Chemie (International ed. in English) 45 (24), 3938, 2006 | 290 | 2006 |
Incorporation of a non-human glycan mediates human susceptibility to a bacterial toxin E Byres, AW Paton, JC Paton, JC Löfling, DF Smith, MCJ Wilce, ... Nature 456 (7222), 648-652, 2008 | 262 | 2008 |
Chemoenzymatic synthesis of CMP–sialic acid derivatives by a one-pot two-enzyme system: comparison of substrate flexibility of three microbial CMP–sialic acid synthetases H Yu, H Yu, R Karpel, X Chen Bioorganic & medicinal chemistry 12 (24), 6427-6435, 2004 | 261 | 2004 |
Amelioration of sepsis by inhibiting sialidase-mediated disruption of the CD24-SiglecG interaction GY Chen, X Chen, S King, KA Cavassani, J Cheng, X Zheng, H Cao, H Yu, ... Nature biotechnology 29 (5), 428-435, 2011 | 206 | 2011 |
Highly efficient chemoenzymatic synthesis of β1–4-linked galactosides with promiscuous bacterial β1–4-galactosyltransferases K Lau, V Thon, H Yu, L Ding, Y Chen, MM Muthana, D Wong, R Huang, ... Chemical communications 46 (33), 6066-6068, 2010 | 203 | 2010 |
One-pot three-enzyme chemoenzymatic approach to the synthesis of sialosides containing natural and non-natural functionalities H Yu, HA Chokhawala, S Huang, X Chen Nature protocols 1 (5), 2485-2492, 2006 | 186 | 2006 |
Novel mechanism for the generation of human xeno-autoantibodies against the nonhuman sialic acid N-glycolylneuraminic acid RE Taylor, CJ Gregg, V Padler-Karavani, D Ghaderi, H Yu, S Huang, ... Journal of Experimental Medicine 207 (8), 1637-1646, 2010 | 177 | 2010 |
Sensitive and specific detection of the non-human sialic Acid N-glycolylneuraminic acid in human tissues and biotherapeutic products SL Diaz, V Padler-Karavani, D Ghaderi, N Hurtado-Ziola, H Yu, X Chen, ... PloS one 4 (1), e4241, 2009 | 174 | 2009 |
Efficient chemoenzymatic synthesis of an N-glycan isomer library L Li, Y Liu, C Ma, J Qu, AD Calderon, B Wu, N Wei, X Wang, Y Guo, ... Chemical science 6 (10), 5652-5661, 2015 | 165 | 2015 |
A Sialyltransferase Mutant with Decreased Donor Hydrolysis and Reduced Sialidase Activities for Directly Sialylating Lewisx G Sugiarto, K Lau, J Qu, Y Li, S Lim, S Mu, JB Ames, AJ Fisher, X Chen ACS chemical biology 7 (7), 1232-1240, 2012 | 165 | 2012 |
Broad and direct interaction between TLR and Siglec families of pattern recognition receptors and its regulation by Neu1 GY Chen, NK Brown, W Wu, Z Khedri, H Yu, X Chen, D Van de Vlekkert, ... elife 3, e04066, 2014 | 156 | 2014 |
Human xeno-autoantibodies against a non-human sialic acid serve as novel serum biomarkers and immunotherapeutics in cancer V Padler-Karavani, N Hurtado-Ziola, M Pu, H Yu, S Huang, S Muthana, ... Cancer research 71 (9), 3352-3363, 2011 | 154 | 2011 |
A sialylated glycan microarray reveals novel interactions of modified sialic acids with proteins and viruses X Song, H Yu, X Chen, Y Lasanajak, MM Tappert, GM Air, VK Tiwari, ... Journal of Biological Chemistry 286 (36), 31610-31622, 2011 | 153 | 2011 |
One-pot multienzyme (OPME) systems for chemoenzymatic synthesis of carbohydrates H Yu, X Chen Organic & biomolecular chemistry 14 (10), 2809-2818, 2016 | 152 | 2016 |
Cross-comparison of protein recognition of sialic acid diversity on two novel sialoglycan microarrays V Padler-Karavani, X Song, H Yu, N Hurtado-Ziola, S Huang, S Muthana, ... Journal of Biological Chemistry 287 (27), 22593-22608, 2012 | 147 | 2012 |
An open receptor-binding cavity of hemagglutinin-esterase-fusion glycoprotein from newly-identified influenza D virus: basis for its broad cell tropism H Song, J Qi, Z Khedri, S Diaz, H Yu, X Chen, A Varki, Y Shi, GF Gao PLoS pathogens 12 (1), e1005411, 2016 | 139 | 2016 |