Luhua Lai

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Jianfeng PeiPeking UniversityE-mailová adresa ověřena na: pku.edu.cn
Renxiao WangFudan UniversityE-mailová adresa ověřena na: fudan.edu.cn
Ping “Andy” Wei - 魏平Shenzhen Institute of Advanced TechnologyE-mailová adresa ověřena na: siat.ac.cn
Chao TangProfessor of Physics, Peking UniversityE-mailová adresa ověřena na: pku.edu.cn
Ziwei DaiAssistant Professor, Southern University of Science and TechnologyE-mailová adresa ověřena na: sustech.edu.cn
Yaxia YuanUniversity of Texas Health Science Center at San AntonioE-mailová adresa ověřena na: uthscsa.edu
Xiaobing DengPeking UinversityE-mailová adresa ověřena na: pku.edu.cn
Kun YangJohns Hopkins School of MedicineE-mailová adresa ověřena na: jhu.edu
Hu MengUniversity of PennsylvaniaE-mailová adresa ověřena na: pennmedicine.upenn.edu
Shuaishi (Sophia) GaoPh.D. student at Center for Quantitative Biology, Peking UniversityE-mailová adresa ověřena na: pku.edu.cn
ZHIJIE LIUJanssen Research & Development, Allergan LLC, Vitae Pharmaceuticals, University of Georgia, Harvard University, Peking UniversityE-mailová adresa ověřena na: its.jnj.com
Shiyong LiuAssociate Professor, Department of Physics, Huazhong University of Science and TechnologyE-mailová adresa ověřena na: mail.hust.edu.cn
Chong HePostdoctoral Research Fellow at Buck Institute for Research on AgingE-mailová adresa ověřena na: buckinstitute.org
Yifei QiFudan UniversityE-mailová adresa ověřena na: fudan.edu.cn
Weizhong LiJ Craig Venter InstituteE-mailová adresa ověřena na: sdsc.edu
Lin JiangAssociate Professor of Neurology, University of California, Los AngelesE-mailová adresa ověřena na: ucla.edu
Hongjun BaiMHRP|HJFE-mailová adresa ověřena na: hivresearch.org
Li-Jia QuPeking UniversityE-mailová adresa ověřena na: pku.edu.cn
Xiaofeng HanWayne State UniversityE-mailová adresa ověřena na: med.wayne.edu
Qingliang LiNational institutes of healthE-mailová adresa ověřena na: ncbi.nlm.nih.gov

Sledovat

Luhua Lai

Professor of Chemistry, Peking University

E-mailová adresa ověřena na: pku.edu.cn - Domovská stránka

biophysical chemistry computational chemical biology protein design drug design


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
Further development and validation of empirical scoring functions for structure-based binding affinity prediction R Wang, L Lai, S Wang Journal of computer-aided molecular design 16, 11-26, 2002	1528	2002
PharmMapper 2017 update: a web server for potential drug target identification with a comprehensive target pharmacophore database X Wang, Y Shen, S Wang, S Li, W Zhang, X Liu, L Lai, J Pei, H Li Nucleic acids research 45 (W1), W356-W360, 2017	1114	2017
Computation of octanol− water partition coefficients by guiding an additive model with knowledge T Cheng, Y Zhao, X Li, F Lin, Y Xu, X Zhang, Y Li, R Wang, L Lai Journal of chemical information and modeling 47 (6), 2140-2148, 2007	874	2007
A new atom-additive method for calculating partition coefficients R Wang, Y Fu, L Lai Journal of chemical information and computer sciences 37 (3), 615-621, 1997	574	1997
LigBuilder: a multi-purpose program for structure-based drug design R Wang, Y Gao, L Lai Molecular modeling annual 6, 498-516, 2000	435	2000
SCORE: A new empirical method for estimating the binding affinity of a protein-ligand complex R Wang, L Liu, L Lai, Y Tang Molecular modeling annual 4, 379-394, 1998	416	1998
Sequence-based prediction of protein protein interaction using a deep-learning algorithm T Sun, B Zhou, L Lai, J Pei BMC bioinformatics 18, 1-8, 2017	412	2017
Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling Z Ge, T Bergonci, Y Zhao, Y Zou, S Du, MC Liu, X Luo, H Ruan, ... Science 358 (6370), 1596-1600, 2017	397	2017
Biosynthesis, purification, and substrate specificity of severe acute respiratory syndrome coronavirus 3C-like proteinase K Fan, P Wei, Q Feng, S Chen, C Huang, L Ma, B Lai, J Pei, Y Liu, J Chen, ... Journal of Biological Chemistry 279 (3), 1637-1642, 2004	394	2004
Deep learning for drug-induced liver injury Y Xu, Z Dai, F Chen, S Gao, J Pei, L Lai Journal of chemical information and modeling 55 (10), 2085-2093, 2015	380	2015
Synthesis, fungicidal activity, and 3D-QSAR of pyridazinone-substituted 1, 3, 4-oxadiazoles and 1, 3, 4-thiadiazoles XJ Zou, LH Lai, GY Jin, ZX Zhang Journal of agricultural and food chemistry 50 (13), 3757-3760, 2002	378	2002
A protein engineered to bind uranyl selectively and with femtomolar affinity L Zhou, M Bosscher, C Zhang, S Özçubukçu, L Zhang, W Zhang, CJ Li, ... Nature chemistry 6 (3), 236-241, 2014	338	2014
Scutellaria baicalensis extract and baicalein inhibit replication of SARS-CoV-2 and its 3C-like protease in vitro H Liu, F Ye, Q Sun, H Liang, C Li, S Li, R Lu, B Huang, W Tan, L Lai Journal of enzyme inhibition and medicinal chemistry 36 (1), 497-503, 2021	335	2021
Transfer learning for drug discovery C Cai, S Wang, Y Xu, W Zhang, K Tang, Q Ouyang, L Lai, J Pei Journal of Medicinal Chemistry 63 (16), 8683-8694, 2020	304	2020
CavityPlus: a web server for protein cavity detection with pharmacophore modelling, allosteric site identification and covalent ligand binding ability prediction Y Xu, S Wang, Q Hu, S Gao, X Ma, W Zhang, Y Shen, F Chen, L Lai, J Pei Nucleic acids research 46 (W1), W374-W379, 2018	296	2018
CH··· O Hydrogen Bonds at Protein-Protein Interfaces* 210 L Jiang, L Lai Journal of Biological Chemistry 277 (40), 37732-37740, 2002	276	2002
Calculating partition coefficient by atom-additive method R Wang, Y Gao, L Lai Perspectives in Drug Discovery and Design 19, 47-66, 2000	268	2000
Deep learning based regression and multiclass models for acute oral toxicity prediction with automatic chemical feature extraction Y Xu, J Pei, L Lai Journal of chemical information and modeling 57 (11), 2672-2685, 2017	249	2017
3C-like proteinase from SARS coronavirus catalyzes substrate hydrolysis by a general base mechanism C Huang, P Wei, K Fan, Y Liu, L Lai Biochemistry 43 (15), 4568-4574, 2004	232	2004
Formation of amyloid fibrils from fully reduced hen egg white lysozyme A Cao, D Hu, L Lai Protein Science 13 (2), 319-324, 2004	229	2004

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