Proteomic and bioinformatic analysis of mammalian SWI/SNF complexes identifies extensive roles in human malignancy C Kadoch, DC Hargreaves, C Hodges, L Elias, L Ho, J Ranish, ... Nature genetics 45 (6), 592-601, 2013 | 1508 | 2013 |
Mammalian SWI/SNF chromatin remodeling complexes and cancer: Mechanistic insights gained from human genomics C Kadoch, GR Crabtree Science advances 1 (5), e1500447, 2015 | 884 | 2015 |
Modular organization and assembly of SWI/SNF family chromatin remodeling complexes N Mashtalir, AR D’Avino, BC Michel, J Luo, J Pan, JE Otto, HJ Zullow, ... Cell 175 (5), 1272-1288. e20, 2018 | 659 | 2018 |
Reversible disruption of mSWI/SNF (BAF) complexes by the SS18-SSX oncogenic fusion in synovial sarcoma C Kadoch, GR Crabtree Cell 153 (1), 71-85, 2013 | 513 | 2013 |
Genome-wide CRISPR screens reveal host factors critical for SARS-CoV-2 infection J Wei, MM Alfajaro, PC DeWeirdt, RE Hanna, WJ Lu-Culligan, WL Cai, ... Cell 184 (1), 76-91. e13, 2021 | 501 | 2021 |
Cancer-specific retargeting of BAF complexes by a prion-like domain G Boulay, GJ Sandoval, N Riggi, S Iyer, R Buisson, B Naigles, ME Awad, ... Cell 171 (1), 163-178. e19, 2017 | 446 | 2017 |
A non-canonical SWI/SNF complex is a synthetic lethal target in cancers driven by BAF complex perturbation BC Michel, AR D’Avino, SH Cassel, N Mashtalir, ZM McKenzie, ... Nature cell biology 20 (12), 1410-1420, 2018 | 363 | 2018 |
Mammalian SWI/SNF chromatin remodeling complexes: emerging mechanisms and therapeutic strategies RC Centore, GJ Sandoval, LMM Soares, C Kadoch, HM Chan Trends in Genetics 36 (12), 936-950, 2020 | 319 | 2020 |
Dynamics of BAF–Polycomb complex opposition on heterochromatin in normal and oncogenic states C Kadoch, RT Williams, JP Calarco, EL Miller, CM Weber, SMG Braun, ... Nature genetics 49 (2), 213-222, 2017 | 310 | 2017 |
SMARCB1 is required for widespread BAF complex–mediated activation of enhancers and bivalent promoters RT Nakayama, JL Pulice, AM Valencia, MJ McBride, ZM McKenzie, ... Nature genetics 49 (11), 1613-1623, 2017 | 284 | 2017 |
CXCL13 plus interleukin 10 is highly specific for the diagnosis of CNS lymphoma JL Rubenstein, VS Wong, C Kadoch, HX Gao, R Barajas, L Chen, ... Blood, The Journal of the American Society of Hematology 121 (23), 4740-4748, 2013 | 251 | 2013 |
The SS18-SSX fusion oncoprotein hijacks BAF complex targeting and function to drive synovial sarcoma MJ McBride, JL Pulice, HC Beird, DR Ingram, AR D’Avino, JF Shern, ... Cancer cell 33 (6), 1128-1141. e7, 2018 | 238 | 2018 |
Chromatin regulatory mechanisms and therapeutic opportunities in cancer AM Valencia, C Kadoch Nature cell biology 21 (2), 152-161, 2019 | 216 | 2019 |
Targeting CDK9 reactivates epigenetically silenced genes in cancer H Zhang, S Pandey, M Travers, H Sun, G Morton, J Madzo, W Chung, ... Cell 175 (5), 1244-1258. e26, 2018 | 215 | 2018 |
Spliceosomal disruption of the non-canonical BAF complex in cancer D Inoue, GL Chew, B Liu, BC Michel, J Pangallo, AR D’Avino, T Hitchman, ... Nature 574 (7778), 432-436, 2019 | 213 | 2019 |
Smarca4 ATPase mutations disrupt direct eviction of PRC1 from chromatin BZ Stanton, C Hodges, JP Calarco, SMG Braun, WL Ku, C Kadoch, ... Nature genetics 49 (2), 282-288, 2017 | 210 | 2017 |
ARID1A determines luminal identity and therapeutic response in estrogen-receptor-positive breast cancer G Xu, S Chhangawala, E Cocco, P Razavi, Y Cai, JE Otto, L Ferrando, ... Nature genetics 52 (2), 198-207, 2020 | 184 | 2020 |
Mammalian SWI/SNF complexes in cancer: emerging therapeutic opportunities RS Pierre, C Kadoch Current opinion in genetics & development 42, 56-67, 2017 | 181 | 2017 |
A novel SS18-SSX fusion-specific antibody for the diagnosis of synovial sarcoma E Baranov, MJ McBride, AM Bellizzi, AH Ligon, CDM Fletcher, C Kadoch, ... The American journal of surgical pathology 44 (7), 922-933, 2020 | 172 | 2020 |
PRC2 and SWI/SNF chromatin remodeling complexes in health and disease C Kadoch, RA Copeland, H Keilhack Biochemistry 55 (11), 1600-1614, 2016 | 172 | 2016 |