Spectrum and prevalence of genetic predisposition in medulloblastoma: a retrospective genetic study and prospective validation in a clinical trial cohort SM Waszak, PA Northcott, I Buchhalter, GW Robinson, C Sutter, ... The Lancet Oncology 19 (6), 785-798, 2018 | 439 | 2018 |
Pan-cancer analysis of somatic copy-number alterations implicates IRS4 and IGF2 in enhancer hijacking J Weischenfeldt, T Dubash, AP Drainas, BR Mardin, Y Chen, AM Stütz, ... Nature genetics 49 (1), 65-74, 2017 | 419 | 2017 |
Tandem fluorescent protein timers for in vivo analysis of protein dynamics A Khmelinskii, PJ Keller, A Bartosik, M Meurer, JD Barry, BR Mardin, ... Nature biotechnology 30 (7), 708-714, 2012 | 319 | 2012 |
Components of the Hippo pathway cooperate with Nek2 kinase to regulate centrosome disjunction BR Mardin, C Lange, JE Baxter, T Hardy, SR Scholz, AM Fry, E Schiebel Nature cell biology 12 (12), 1166-1176, 2010 | 218 | 2010 |
Plk1 controls the Nek2A-PP1γ antagonism in centrosome disjunction BR Mardin, FG Agircan, C Lange, E Schiebel Current Biology 21 (13), 1145-1151, 2011 | 174 | 2011 |
A cell‐based model system links chromothripsis with hyperploidy BR Mardin, AP Drainas, SM Waszak, J Weischenfeldt, M Isokane, ... Molecular systems biology 11 (9), 828, 2015 | 154 | 2015 |
Breaking the ties that bind: new advances in centrosome biology BR Mardin, E Schiebel Journal of Cell Biology 197 (1), 11-18, 2012 | 149 | 2012 |
Separate to operate: control of centrosome positioning and separation FG Agircan, E Schiebel, BR Mardin Philosophical Transactions of the Royal Society B: Biological Sciences 369 …, 2014 | 141 | 2014 |
Negative selection and chromosome instability induced by Mad2 overexpression delay breast cancer but facilitate oncogene-independent outgrowth K Rowald, M Mantovan, J Passos, C Buccitelli, BR Mardin, JO Korbel, ... Cell reports 15 (12), 2679-2691, 2016 | 86 | 2016 |
Single-cell analysis of structural variations and complex rearrangements with tri-channel processing AD Sanders, S Meiers, M Ghareghani, D Porubsky, H Jeong, ... Nature biotechnology 38 (3), 343-354, 2020 | 75 | 2020 |
EGF-induced centrosome separation promotes mitotic progression and cell survival BR Mardin, M Isokane, MR Cosenza, A Krämer, J Ellenberg, AM Fry, ... Developmental cell 25 (3), 229-240, 2013 | 73 | 2013 |
Pan-cancer analysis distinguishes transcriptional changes of aneuploidy from proliferation C Buccitelli, L Salgueiro, K Rowald, R Sotillo, BR Mardin, JO Korbel Genome research 27 (4), 501-511, 2017 | 63 | 2017 |
Systems approaches identify the consequences of monosomy in somatic human cells NK Chunduri, P Menges, X Zhang, A Wieland, VL Gotsmann, BR Mardin, ... Nature communications 12 (1), 5576, 2021 | 49 | 2021 |
A scalable CRISPR/Cas9-based fluorescent reporter assay to study DNA double-strand break repair choice P Roidos, S Sungalee, S Benfatto, Ö Serçin, AM Stütz, A Abdollahi, ... Nature communications 11 (1), 4077, 2020 | 42 | 2020 |
Identification of ZCCHC8 as fusion partner of ROS1 in a case of congenital glioblastoma multiforme with a t(6;12)(q21;q24.3) MC Coccé, BR Mardin, S Bens, AM Stütz, F Lubieniecki, I Vater, JO Korbel, ... Genes, Chromosomes and Cancer 55 (9), 677-687, 2016 | 41 | 2016 |
Immortalization capacity of HPV types is inversely related to chromosomal instability DM Schütze, O Krijgsman, PJF Snijders, B Ylstra, J Weischenfeldt, ... Oncotarget 7 (25), 37608, 2016 | 30 | 2016 |
Genome-wide screens implicate loss of cullin ring ligase 3 in persistent proliferation and genome instability in TP53-deficient cells AP Drainas, RA Lambuta, I Ivanova, Ö Serçin, I Sarropoulos, ML Smith, ... Cell Reports 31 (1), 2020 | 27 | 2020 |
Somatic structural variant formation is guided by and influences genome architecture N Sidiropoulos, BR Mardin, FG Rodríguez-González, ID Bochkov, S Garg, ... Genome research 32 (4), 643-655, 2022 | 23 | 2022 |
Uncovering cancer vulnerabilities by machine learning prediction of synthetic lethality S Benfatto, Ö Serçin, FR Dejure, A Abdollahi, FT Zenke, BR Mardin Molecular Cancer 20 (1), 111, 2021 | 21 | 2021 |
A solid‐phase transfection platform for arrayed CRISPR screens Ö Serçin, S Reither, P Roidos, N Ballin, S Palikyras, A Baginska, K Rein, ... Molecular systems biology 15 (12), e8983, 2019 | 12 | 2019 |