A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion M Harterink, F Port, MJ Lorenowicz, IJ McGough, M Silhankova, MC Betist, ... Nature cell biology 13 (8), 914-923, 2011 | 395 | 2011 |
Neuroblast migration along the anteroposterior axis of C. elegans is controlled by opposing gradients of Wnts and a secreted Frizzled-related protein M Harterink, DH Kim, TC Middelkoop, TD Doan, A van Oudenaarden, ... Development 138 (14), 2915-2924, 2011 | 126 | 2011 |
Feedback control of gene expression variability in the Caenorhabditis elegans Wnt pathway N Ji, TC Middelkoop, RA Mentink, MC Betist, S Tonegawa, D Mooijman, ... Cell 155 (4), 869-880, 2013 | 95 | 2013 |
Actomyosin-driven left-right asymmetry: from molecular torques to chiral self organization SR Naganathan, TC Middelkoop, S Fürthauer, SW Grill Current opinion in cell biology 38, 24-30, 2016 | 80 | 2016 |
Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy DF Kelly, RJ Lake, TC Middelkoop, HY Fan, S Artavanis-Tsakonas, ... PloS one 5 (5), e10532, 2010 | 57 | 2010 |
Cell intrinsic modulation of Wnt signaling controls neuroblast migration in C. elegans RA Mentink, TC Middelkoop, L Rella, N Ji, CY Tang, MC Betist, ... Developmental cell 31 (2), 188-201, 2014 | 52 | 2014 |
Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early Caenorhabditis elegans development LG Pimpale, TC Middelkoop, A Mietke, SW Grill Elife 9, e54930, 2020 | 49 | 2020 |
Development and migration of the C. elegans Q neuroblasts and their descendants TC Middelkoop, HC Korswagen WormBook: The Online Review of C. elegans Biology [Internet], 2018 | 43 | 2018 |
The thrombospondin repeat containing protein MIG-21 controls a left–right asymmetric Wnt signaling response in migrating C. elegans neuroblasts TC Middelkoop, L Williams, PT Yang, J Luchtenberg, MC Betist, N Ji, ... Developmental biology 361 (2), 338-348, 2012 | 40 | 2012 |
Caenorhabditis elegans Cyclin D/CDK4 and Cyclin E/CDK2 Induce Distinct Cell Cycle Re-Entry Programs in Differentiated Muscle Cells J Korzelius, I The, S Ruijtenberg, MBW Prinsen, V Portegijs, ... PLoS genetics 7 (11), e1002362, 2011 | 35 | 2011 |
Inhibition of late endosomal maturation restores Wnt secretion in Caenorhabditis elegans vps-29 retromer mutants MJ Lorenowicz, M Macurkova, M Harterink, TC Middelkoop, R de Groot, ... Cellular Signalling 26 (1), 19-31, 2014 | 30 | 2014 |
UNC-4 antagonizes Wnt signaling to regulate synaptic choice in the C. elegans motor circuit J Schneider, RL Skelton, SE Von Stetina, TC Middelkoop, ... Development 139 (12), 2234-2245, 2012 | 23 | 2012 |
CYK-1/Formin activation in cortical RhoA signaling centers promotes organismal left–right symmetry breaking TC Middelkoop, J Garcia-Baucells, P Quintero-Cadena, LG Pimpale, ... Proceedings of the National Academy of Sciences 118 (20), e2021814118, 2021 | 21 | 2021 |
Partially overlapping guidance pathways focus the activity of UNC-40/DCC along the anteroposterior axis of polarizing neuroblasts A Ebbing, TC Middelkoop, MC Betist, E Bodewes, HC Korswagen Development 146 (18), dev180059, 2019 | 16 | 2019 |
A cytokinetic ring-driven cell rotation achieves Hertwig’s rule in early development TC Middelkoop, J Neipel, CE Cornell, R Naumann, LG Pimpale, ... Proceedings of the National Academy of Sciences 121 (25), e2318838121, 2024 | 5 | 2024 |
Caenorhabditis elegans SEL-5/AAK1 regulates cell migration and cell outgrowth independently of its kinase activity F Knop, A Zounarová, V Šabata, TC Middelkoop, M Macůrková Elife 13, e91054, 2024 | 2 | 2024 |
Organocatalytic asymmetric tandem reaction for the enantioselective synthesis of chiral oxindoles to construct CyK dyes L Wang, ZH Li, D Wu, RT Ge, J Zhou, YF Zhang, SY Zhang Chem Catalysis, 2024 | 1 | 2024 |
Governing principles of transcriptional logic out of equilibrium S Dixit, TC Middelkoop, S Choubey Biophysical Journal 123 (8), 1015-1029, 2024 | 1 | 2024 |
Anillin promotes actomyosin contractility by mechanical tethering P Slikova, A Beber, S Tomasova, TC Middelkoop, A Akandwanaho, ... Biophysical Journal 123 (3), 47a, 2024 | | 2024 |
Cell lineage-dependent chiral actomyosin flows drive cellular rearrangements in early development L Pimpale, TC Middelkoop, A Mietke, SW Grill BioRxiv, 842922, 2019 | | 2019 |