Steps toward mapping the human vasculature by phage display W Arap, MG Kolonin, M Trepel, J Lahdenranta, M Cardó-Vila, ... Nature medicine 8 (2), 121-127, 2002 | 774 | 2002 |
CD13/APN is activated by angiogenic signals and is essential for capillary tube formation SV Bhagwat, J Lahdenranta, R Giordano, W Arap, R Pasqualini, ... Blood, The Journal of the American Society of Hematology 97 (3), 652-659, 2001 | 396 | 2001 |
Biopanning and rapid analysis of selective interactive ligands RJ Giordano, M Cardó-Vila, J Lahdenranta, R Pasqualini, W Arap Nature medicine 7 (11), 1249-1253, 2001 | 372 | 2001 |
Diverse point mutations in the human glucose-6-phosphate dehydrogenase gene cause enzyme deficiency and mild or severe hemolytic anemia. TJ Vulliamy, M D'urso, G Battistuzzi, M Estrada, NS Foulkes, G Martini, ... Proceedings of the National Academy of Sciences 85 (14), 5171-5175, 1988 | 320 | 1988 |
Next-generation phage display: integrating and comparing available molecular tools to enable cost-effective high-throughput analysis E Dias-Neto, DN Nunes, RJ Giordano, J Sun, GH Botz, K Yang, ... PloS one 4 (12), e8338, 2009 | 189 | 2009 |
Aminopeptidase A is a functional target in angiogenic blood vessels S Marchiò, J Lahdenranta, RO Schlingemann, D Valdembri, P Wesseling, ... Cancer cell 5 (2), 151-162, 2004 | 164 | 2004 |
Infection by Trypanosoma cruzi: identification of a parasite ligand and its host cell receptor MH Magdesian, R Giordano, H Ulrich, MA Juliano, L Juliano, ... Journal of Biological Chemistry 276 (22), 19382-19389, 2001 | 151 | 2001 |
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment L Guzman-Rojas, R Rangel, A Salameh, JK Edwards, E Dondossola, ... Proceedings of the National Academy of Sciences 109 (5), 1637-1642, 2012 | 146 | 2012 |
Impaired angiogenesis in aminopeptidase N-null mice R Rangel, Y Sun, L Guzman-Rojas, MG Ozawa, J Sun, RJ Giordano, ... Proceedings of the National Academy of Sciences 104 (11), 4588-4593, 2007 | 145 | 2007 |
Targeted Induction of Lung Endothelial Cell Apoptosis Causes Emphysema-like Changes in the Mouse∗ RJ Giordano, J Lahdenranta, L Zhen, U Chukwueke, I Petrache, ... Journal of Biological Chemistry 283 (43), 29447-29460, 2008 | 137 | 2008 |
Cloning of a surface membrane glycoprotein specific for the infective form of Trypanosoma cruzi having adhesive properties to laminin R Giordano, DL Fouts, D Tewari, W Colli, JE Manning, MJM Alves Journal of Biological Chemistry 274 (6), 3461-3468, 1999 | 129 | 1999 |
Ligand-directed surface profiling of human cancer cells with combinatorial peptide libraries MG Kolonin, L Bover, J Sun, AJ Zurita, KA Do, J Lahdenranta, ... Cancer research 66 (1), 34-40, 2006 | 97 | 2006 |
Design and validation of a bifunctional ligand display system for receptor targeting L Chen, AJ Zurita, PU Ardelt, RJ Giordano, W Arap, R Pasqualini Chemistry & biology 11 (8), 1081-1091, 2004 | 95 | 2004 |
An acidic component of the heterogeneous Tc-85 protein family from the surface of Trypanosoma cruzi is a laminin binding glycoprotein R Giordano, R Chammas, SS Veiga, W Colli Molecular and Biochemical Parasitology 65 (1), 85-94, 1994 | 86 | 1994 |
From combinatorial peptide selection to drug prototype (I): targeting the vascular endothelial growth factor receptor pathway RJ Giordano, M Cardó-Vila, A Salameh, CD Anobom, BD Zeitlin, ... Proceedings of the National Academy of Sciences 107 (11), 5112-5117, 2010 | 85 | 2010 |
Role of the gp85/Trans-Sialidases in Trypanosoma cruzi Tissue Tropism: Preferential Binding of a Conserved Peptide Motif to the Vasculature In Vivo RR Tonelli, RJ Giordano, EM Barbu, AC Torrecilhas, GS Kobayashi, ... PLoS neglected tropical diseases 4 (11), e864, 2010 | 75 | 2010 |
From combinatorial peptide selection to drug prototype (II): targeting the epidermal growth factor receptor pathway M Cardó-Vila, RJ Giordano, RL Sidman, LF Bronk, Z Fan, J Mendelsohn, ... Proceedings of the National Academy of Sciences 107 (11), 5118-5123, 2010 | 70 | 2010 |
Targeting the interleukin‐11 receptor α in metastatic prostate cancer: A first‐in‐man study R Pasqualini, RE Millikan, DR Christianson, M Cardó‐Vila, WHP Driessen, ... Cancer 121 (14), 2411-2421, 2015 | 59 | 2015 |
Structural basis for the interaction of a vascular endothelial growth factor mimic peptide motif and its corresponding receptors RJ Giordano, CD Anobom, M Cardó-Vila, J Kalil, AP Valente, ... Chemistry & biology 12 (10), 1075-1083, 2005 | 59 | 2005 |
The peptidomimetic Vasotide targets two retinal VEGF receptors and reduces pathological angiogenesis in murine and nonhuman primate models of retinal disease RL Sidman, J Li, M Lawrence, W Hu, GF Musso, RJ Giordano, ... Science translational medicine 7 (309), 309ra165-309ra165, 2015 | 58 | 2015 |