BET domain co-regulators in obesity, inflammation and cancer AC Belkina, GV Denis Nature reviews Cancer 12 (7), 465-477, 2012 | 802 | 2012 |
B cells promote inflammation in obesity and type 2 diabetes through regulation of T-cell function and an inflammatory cytokine profile J DeFuria, AC Belkina, M Jagannathan-Bogdan, J Snyder-Cappione, ... Proceedings of the National Academy of Sciences 110 (13), 5133-5138, 2013 | 604 | 2013 |
Automated optimized parameters for T-distributed stochastic neighbor embedding improve visualization and analysis of large datasets AC Belkina, CO Ciccolella, R Anno, R Halpert, J Spidlen, ... Nature communications 10 (1), 5415, 2019 | 554 | 2019 |
Metformin enhances autophagy and normalizes mitochondrial function to alleviate aging-associated inflammation LP Bharath, M Agrawal, G McCambridge, DA Nicholas, H Hasturk, J Liu, ... Cell metabolism 32 (1), 44-55. e6, 2020 | 477 | 2020 |
BET protein function is required for inflammation: Brd2 genetic disruption and BET inhibitor JQ1 impair mouse macrophage inflammatory responses AC Belkina, BS Nikolajczyk, GV Denis The Journal of Immunology 190 (7), 3670-3678, 2013 | 455 | 2013 |
BET bromodomain inhibition as a novel strategy for reactivation of HIV-1 C Banerjee, N Archin, D Michaels, AC Belkina, GV Denis, J Bradner, ... Journal of leukocyte biology 92 (6), 1147-1154, 2012 | 354 | 2012 |
Brd2 disruption in mice causes severe obesity without Type 2 diabetes F Wang, H Liu, WP Blanton, A Belkina, NK Lebrasseur, GV Denis Biochemical Journal 425 (1), 71-85, 2010 | 276 | 2010 |
Clinical trials for BET inhibitors run ahead of the science G Andrieu, AC Belkina, GV Denis Drug Discovery Today: Technologies 19, 45-50, 2016 | 274 | 2016 |
Th17 cytokines differentiate obesity from obesity‐associated type 2 diabetes and promote TNF α production B Ip, NA Cilfone, AC Belkina, J DeFuria, M Jagannathan‐Bogdan, M Zhu, ... Obesity 24 (1), 102-112, 2016 | 142 | 2016 |
Fatty acid metabolites combine with reduced β oxidation to activate Th17 inflammation in human type 2 diabetes DA Nicholas, EA Proctor, M Agrawal, AC Belkina, SC Van Nostrand, ... Cell metabolism 30 (3), 447-461. e5, 2019 | 139 | 2019 |
Obesity genes and insulin resistance AC Belkina, GV Denis Current Opinion in Endocrinology, Diabetes and Obesity 17 (5), 472-477, 2010 | 104 | 2010 |
Lung-resident memory B cells protect against bacterial pneumonia KA Barker, NS Etesami, AT Shenoy, EI Arafa, CL de Ana, NMS Smith, ... The Journal of clinical investigation 131 (11), 2021 | 100 | 2021 |
Antigen presentation by lung epithelial cells directs CD4+ TRM cell function and regulates barrier immunity AT Shenoy, C Lyon De Ana, EI Arafa, I Salwig, KA Barker, FT Korkmaz, ... Nature Communications 12 (1), 5834, 2021 | 90 | 2021 |
BET bromodomain proteins Brd2, Brd3 and Brd4 selectively regulate metabolic pathways in the pancreatic β-cell JT Deeney, AC Belkina, OS Shirihai, BE Corkey, GV Denis PloS one 11 (3), e0151329, 2016 | 85 | 2016 |
HIV-1 intron-containing RNA expression induces innate immune activation and T cell dysfunction H Akiyama, CM Miller, CR Ettinger, AC Belkina, JE Snyder-Cappione, ... Nature communications 9 (1), 3450, 2018 | 81 | 2018 |
Pneumonia recovery reprograms the alveolar macrophage pool A Guillon, EI Arafa, KA Barker, AC Belkina, I Martin, AT Shenoy, ... JCI insight 5 (4), 2020 | 66 | 2020 |
The double bromodomain protein Brd2 promotes B cell expansion and mitogenesis AC Belkina, WP Blanton, BS Nikolajczyk, GV Denis Journal of Leukocyte Biology 95 (3), 451-460, 2014 | 63 | 2014 |
BET protein targeting suppresses the PD-1/PD-L1 pathway in triple-negative breast cancer and elicits anti-tumor immune response GP Andrieu, JS Shafran, CL Smith, AC Belkina, AN Casey, N Jafari, ... Cancer letters 465, 45-58, 2019 | 61 | 2019 |
Functional and genomic analyses reveal therapeutic potential of targeting β-catenin/CBP activity in head and neck cancer VK Kartha, KA Alamoud, K Sadykov, BC Nguyen, F Laroche, H Feng, ... Genome medicine 10, 1-18, 2018 | 52 | 2018 |
B cells promote obesity-associated periodontitis and oral pathogen-associated inflammation M Zhu, AC Belkina, J DeFuria, JD Carr, TE Van Dyke, R Gyurko, ... Journal of Leukocyte Biology 96 (2), 349-357, 2014 | 48 | 2014 |