| RNA maps reveal new RNA classes and a possible function for pervasive transcription P Kapranov, J Cheng, S Dike, DA Nix, R Duttagupta, AT Willingham, ... Science 316 (5830), 1484-1488, 2007 | 2999 | 2007 |
| The developmental transcriptome of Drosophila melanogaster BR Graveley, AN Brooks, JW Carlson, MO Duff, JM Landolin, L Yang, ... Nature 471 (7339), 473-479, 2011 | 1718 | 2011 |
| Identification of Functional Elements and Regulatory Circuits by Drosophila modENCODE modENCODE Consortium, S Roy, J Ernst, PV Kharchenko, P Kheradpour, ... Science 330 (6012), 1787-1797, 2010 | 1113 | 2010 |
| A strategy for probing the function of noncoding RNAs finds a repressor of NFAT AT Willingham, AP Orth, S Batalov, EC Peters, BG Wen, P Aza-Blanc, ... Science 309 (5740), 1570-1573, 2005 | 876 | 2005 |
| Genome-wide transcription and the implications for genomic organization P Kapranov, AT Willingham, TR Gingeras Nature Reviews Genetics 8 (6), 413-423, 2007 | 873 | 2007 |
| A Drosophila mechanosensory transduction channel RG Walker, AT Willingham, CS Zuker Science 287 (5461), 2229-2234, 2000 | 858 | 2000 |
| The transcriptional diversity of 25 Drosophila cell lines L Cherbas, A Willingham, D Zhang, L Yang, Y Zou, BD Eads, JW Carlson, ... Genome research 21 (2), 301-314, 2011 | 293 | 2011 |
| Post-transcriptional processing generates a diversity of 5′-modified long and short RNAs: affymetrix/cold Spring Harbor Laboratory ENCODE Transcriptome Project K Fejes-Toth, V Sotirova, R Sachidanandam, G Assaf, GJ Hannon, ... Nature 457 (7232), 1028, 2009 | 293 | 2009 |
| TUF love for “junk” DNA AT Willingham, TR Gingeras Cell 125 (7), 1215-1220, 2006 | 209 | 2006 |
| Nucleobase and ribose modifications control immunostimulation by a microRNA-122-mimetic RNA H Peacock, RV Fucini, P Jayalath, JM Ibarra-Soza, HJ Haringsma, ... Journal of the American Chemical Society 133 (24), 9200-9203, 2011 | 112 | 2011 |
| siRNA-optimized modifications for enhanced in vivo activity DM Kenski, G Butora, AT Willingham, AJ Cooper, W Fu, N Qi, F Soriano, ... Molecular therapy Nucleic acids 1, 2012 | 103 | 2012 |
| RNAi and HTS: exploring cancer by systematic loss-of-function AT Willingham, QL Deveraux, GM Hampton, P Aza-Blanc Oncogene 23 (51), 8392-8400, 2004 | 92 | 2004 |
| Analysis of acyclic nucleoside modifications in siRNAs finds sensitivity at position 1 that is restored by 5′-terminal phosphorylation both in vitro and in vivo DM Kenski, AJ Cooper, JJ Li, AT Willingham, HJ Haringsma, TA Young, ... Nucleic acids research 38 (2), 660-671, 2010 | 89 | 2010 |
| RNA interference mediated inhibition of gene expression using short interfering nucleic acids (siNA) M Cancilla, JJ Cunningham, MW Flanagan, HJ Haringsma, D Kenski, ... US Patent 9,260,471, 2016 | 68 | 2016 |
| mRNA knockdown by single strand RNA is improved by chemical modifications HJ Haringsma, JJ Li, F Soriano, DM Kenski, WM Flanagan, AT Willingham Nucleic acids research 40 (9), 4125-4136, 2012 | 60 | 2012 |
| Characterization of MK-4166, a clinical agonistic antibody that targets human GITR and inhibits the generation and suppressive effects of T regulatory cells S Sukumar, DC Wilson, Y Yu, J Wong, S Naravula, G Ermakov, R Riener, ... Cancer Research 77 (16), 4378-4388, 2017 | 59 | 2017 |
| A tissue specific cytochrome P450 required for the structure and function of Drosophila sensory organs AT Willingham, T Keil Mechanisms of development 121 (10), 1289-1297, 2004 | 56 | 2004 |
| Single-stranded microRNA mimics G Chorn, M Klein-McDowell, L Zhao, MA Saunders, WM Flanagan, ... Rna 18 (10), 1796-1804, 2012 | 55 | 2012 |
| Establishment of engineered cell-based assays mediating LAG3 and PD1 immune suppression enables potency measurement of blocking antibodies and assessment of signal transduction B Bhagwat, H Cherwinski, M Sathe, W Seghezzi, TK McClanahan, ... Journal of immunological methods 456, 7-14, 2018 | 45 | 2018 |
| Single-stranded RNAi agents containing an internal, non-nucleic acid spacer L Lim, G Chorn, A Willingham, L Zhao US Patent 9,243,246, 2016 | 32 | 2016 |
Thomas GingerasProfessor of Functional Genomics, Cold Spring Harbor LaboratoryE-mailová adresa ověřena na: cshl.edu
