Rama Khokha

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Josef PenningerLife Sciences Institute, University of British Columbia / IMBA Institut für MolekulareE-mailová adresa ověřena na: imba.oeaw.ac.at
Jimmie E. FataAssociate Professor, Department of Biology, College of Staten Island, City University of New YorkE-mailová adresa ověřena na: csi.cuny.edu
Purna JoshiUniversity of Texas at DallasE-mailová adresa ověřena na: utdallas.edu
Sam MolyneuxUniversity of TorontoE-mailová adresa ověřena na: uhnres.utoronto.ca
Ming TsaoUniversity of Toronto, University Health Network, Princess Margaret Cancer CentreE-mailová adresa ověřena na: uhn.ca
Alexander BeristainAssistant Professor, The University of British ColumbiaE-mailová adresa ověřena na: mail.ubc.ca
Peeyush Laladepartment of anatomy and cell biology, university of western ontarioE-mailová adresa ověřena na: uwo.ca
Peter H Backxdepartment of biology York universityE-mailová adresa ověřena na: yorku.ca
Trevor McKeeAdjunct Lecturer, Department of Laboratory Medicine and Pathobiology, University of TorontoE-mailová adresa ověřena na: utoronto.ca
Andrew Tri Van HoScientist, Association Institut de Myologie, INSERM UMRS974, Sorbonne UniversitéE-mailová adresa ověřena na: sorbonne-universite.fr
Gordon DuncanTreadwell Therapeutics Inc. , Toronto, CanadaE-mailová adresa ověřena na: treadwelltx.com
S. Jeffrey DixonDistinguished University Professor Emeritus, Western University, London, CanadaE-mailová adresa ověřena na: schulich.uwo.ca
Stefano MeniniDepartment of Clinical and Molecular Medicine, Sapienza University of RomeE-mailová adresa ověřena na: uniroma1.it
CJ OrmandyFounder and Director MammBio Pty Ltd and Visiting Scientist Garvan Institute of Medical ResearchE-mailová adresa ověřena na: garvan.org.au
Daniel SchramekSenior Investigator & Deputy Director Sinai Health/Assoc. Prof. University of TorontoE-mailová adresa ověřena na: lunenfeld.ca
James W. DennisProfessor of Molecular Genetics, University of TorontoE-mailová adresa ověřena na: lunenfeld.ca
Marta Letizia HribalUniversità di Catanzaro Magna GraeciaE-mailová adresa ověřena na: unicz.it
Paul W.M. Fedak, M.D. Ph.D.University of Calgary and Northwestern UniversityE-mailová adresa ověřena na: ucalgary.ca

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Rama Khokha

Professor, University of Toronto, Ontario cancer institute

E-mailová adresa ověřena na: uhnres.utoronto.ca

metalloproteinases stem cells inflammation cancer metastasis


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
Regulation of cancer cell migration and bone metastasis by RANKL DH Jones, T Nakashima, OH Sanchez, I Kozieradzki, SV Komarova, ... Nature 440 (7084), 692-696, 2006	1021	2006
Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ... Cancer cell 27 (2), 211-222, 2015	1017	2015
The osteoclast differentiation factor osteoprotegerin-ligand is essential for mammary gland development JE Fata, YY Kong, J Li, T Sasaki, J Irie-Sasaki, RA Moorehead, R Elliott, ... Cell 103 (1), 41-50, 2000	991	2000
Progesterone induces adult mammary stem cell expansion PA Joshi, HW Jackson, AG Beristain, MA Di Grappa, PA Mote, CL Clarke, ... Nature 465 (7299), 803-807, 2010	796	2010
Suppression of tumor growth and metastasis in Mgat5-deficient mice M Granovsky, J Fata, J Pawling, WJ Muller, R Khokha, JW Dennis Nature medicine 6 (3), 306-312, 2000	675	2000
Osteoclast differentiation factor RANKL controls development of progestin-driven mammary cancer D Schramek, A Leibbrandt, V Sigl, L Kenner, JA Pospisilik, HJ Lee, ... Nature 468 (7320), 98-102, 2010	655	2010
Metalloproteinases and their natural inhibitors in inflammation and immunity R Khokha, A Murthy, A Weiss Nature Reviews Immunology 13 (9), 649-665, 2013	640	2013
Tissue inhibitor of metalloproteinases-3 (TIMP-3) is an extracellular matrix-associated protein with a distinctive pattern of expression in mouse cells and tissues. KJ Leco, R Khokha, N Pavloff, SP Hawkes, DR Edwards Journal of Biological Chemistry 269 (12), 9352-9360, 1994	636	1994
Antisense RNA-induced reduction in murine TIMP levels confers oncogenicity on Swiss 3T3 cells R Khokha, P Waterhouse, S Yagel, PK Lala, CM Overall, G Norton, ... Science 243 (4893), 947-950, 1989	593	1989
Tumor necrosis factor-α mediates cardiac remodeling and ventricular dysfunction after pressure overload state M Sun, M Chen, F Dawood, U Zurawska, JY Li, T Parker, Z Kassiri, ... Circulation 115 (11), 1398-1407, 2007	505	2007
TIMPs: versatile extracellular regulators in cancer HW Jackson, V Defamie, P Waterhouse, R Khokha Nature Reviews Cancer 17 (1), 38-53, 2017	459	2017
The association of measured breast tissue characteristics with mammographic density and other risk factors for breast cancer T Li, L Sun, N Miller, T Nicklee, J Woo, L Hulse-Smith, MS Tsao, R Khokha, ... Cancer Epidemiology Biomarkers & Prevention 14 (2), 343-349, 2005	427	2005
RhoC is dispensable for embryogenesis and tumor initiation but essential for metastasis A Hakem, O Sanchez-Sweatman, A You-Ten, G Duncan, A Wakeham, ... Genes & development 19 (17), 1974-1979, 2005	400	2005
iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS DR McIlwain, PA Lang, T Maretzky, K Hamada, K Ohishi, SK Maney, ... Science 335 (6065), 229-232, 2012	376	2012
Molecular mechanisms of tumor invasion and metastasis: an integrated view RA Cairns, R Khokha, RP Hill Current molecular medicine 3 (7), 659-671, 2003	368	2003
Binding to EGF receptor of a laminin-5 EGF-like fragment liberated during MMP-dependent mammary gland involution S Schenk, E Hintermann, M Bilban, N Koshikawa, C Hojilla, R Khokha, ... The Journal of cell biology 161 (1), 197-209, 2003	363	2003
Steps in tumor metastasis: new concepts from intravital videomicroscopy AF Chambers, IC MacDonald, EE Schmidt, S Koop, VL Morris, R Khokha, ... Cancer and Metastasis Reviews 14, 279-301, 1995	359	1995
Abnormal TNF activity in Timp3^−/− mice leads to chronic hepatic inflammation and failure of liver regeneration FF Mohammed, DS Smookler, SEM Taylor, B Fingleton, Z Kassiri, ... Nature genetics 36 (9), 969-977, 2004	354	2004
Spontaneous air space enlargement in the lungs of mice lacking tissue inhibitor of metalloproteinases-3 (TIMP-3) KJ Leco, P Waterhouse, OH Sanchez, KLM Gowing, AR Poole, ... The Journal of clinical investigation 108 (6), 817-829, 2001	352	2001
Tryptophan-derived microbial metabolites activate the aryl hydrocarbon receptor in tumor-associated macrophages to suppress anti-tumor immunity K Hezaveh, RS Shinde, A Klötgen, MJ Halaby, S Lamorte, R Quevedo, ... Immunity 55 (2), 324-340. e8, 2022	340	2022

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