Hypoxia-sensitive metal β-ketoiminato complexes showing induced single-strand DNA breaks and cancer cell death by apoptosis RM Lord, AJ Hebden, CM Pask, IR Henderson, SJ Allison, SL Shepherd, ... Journal of Medicinal Chemistry 58 (12), 4940-4953, 2015 | 71 | 2015 |
Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing N-heterocyclic carbene ligands SJ Allison, M Sadiq, E Baronou, PA Cooper, C Dunnill, NT Georgopoulos, ... Cancer letters 403, 98-107, 2017 | 70 | 2017 |
Anticancer metallohelices: nanomolar potency and high selectivity RA Kaner, SJ Allison, AD Faulkner, RM Phillips, DI Roper, SL Shepherd, ... Chemical Science 7 (2), 951-958, 2016 | 57 | 2016 |
Ruthenium‐containing linear helicates and mesocates with tuneable p53‐selective cytotoxicity in colorectal cancer cells SJ Allison, D Cooke, FS Davidson, PIP Elliott, RA Faulkner, HBS Griffiths, ... Angewandte Chemie International Edition 57 (31), 9799-9804, 2018 | 46 | 2018 |
Discovery of selective, antimetastatic and anti-cancer stem cell metallohelices via post-assembly modification H Song, NJ Rogers, SJ Allison, V Brabec, H Bridgewater, H Kostrhunova, ... Chemical Science 10 (37), 8547-8557, 2019 | 33 | 2019 |
Neutral and cationic half-sandwich arene ruthenium, Cp* Rh and Cp* Ir oximato and oxime complexes: Synthesis, structural, DFT and biological studies S Adhikari, NR Palepu, D Sutradhar, SL Shepherd, RM Phillips, ... Journal of Organometallic Chemistry 820, 70-81, 2016 | 30 | 2016 |
Synthesis, Structural and Biological Studies of Some Half‐Sandwich d6‐Metal Complexes with Pyrimidine‐Based Ligands BPR Aradhyula, M Kalidasan, K Gangele, DK Deb, SL Shepherd, ... ChemistrySelect 2 (6), 2065-2076, 2017 | 23 | 2017 |
Silver (I) N-Heterocyclic Carbene Complexes Derived from Clotrimazole: Antiproliferative Activity and Interaction with an Artificial Membrane-Based Biosensor HA Mohamed, S Shepherd, N William, HA Blundell, M Das, CM Pask, ... Organometallics 39 (8), 1318-1331, 2020 | 20 | 2020 |
Synthesis, structural, DFT calculations and biological studies of rhodium and iridium complexes containing azine Schiff-base ligands S Adhikari, D Sutradhar, SL Shepherd, RM Phillips, AK Chandra, KM Rao Polyhedron 117, 404-414, 2016 | 20 | 2016 |
Triazole-based, optically-pure metallosupramolecules; highly potent and selective anticancer compounds H Song, NJ Rogers, V Brabec, GJ Clarkson, JPC Coverdale, ... Chemical Communications 56 (47), 6392-6395, 2020 | 18 | 2020 |
Half‐sandwich ruthenium, rhodium and iridium complexes featuring oxime ligands: Structural studies and preliminary investigation of in vitro and in vivo anti … NR Palepu, S Adhikari, AK Verma, SL Shepherd, RM Phillips, ... Applied Organometallic Chemistry 31 (7), e3640, 2017 | 18 | 2017 |
Glycoconjugated metallohelices have improved nuclear delivery and suppress tumour growth in vivo H Song, SJ Allison, V Brabec, HE Bridgewater, J Kasparkova, ... Angewandte Chemie 132 (34), 14785-14793, 2020 | 11 | 2020 |
Polymer encapsulation of anticancer silver–N-heterocyclic carbene complexes HA Mohamed, M Khuphe, SJ Boardman, S Shepherd, RM Phillips, ... RSC advances 8 (19), 10474-10477, 2018 | 9 | 2018 |
Corrigendum to" Preclinical anti-cancer activity and multiple mechanisms of action of a cationic silver complex bearing n-heterocyclic carbene ligands"[canc. Lett. 403 (2017 … SJ Allison, M Sadiq, E Baronou, PA Cooper, C Dunnill, NT Georgopoulos, ... Cancer letters 431, 247, 2018 | 3 | 2018 |
Ruthenium terpyridine Phenol-Substituent supports PCET and semiquinone-like behavior KL Moffa, CN Teahan, CL Montgomery, SL Shepherd, JC Dickenson, ... Polyhedron 244, 116582, 2023 | 1 | 2023 |
Dicobalt (ii) helices kill colon cancer cells via enantiomer-specific mechanisms; DNA damage or microtubule disruption H Song, H Kostrhunova, J Cervinka, J Macpherson, J Malina, T Rajan, ... Chemical Science 15 (28), 11029-11037, 2024 | | 2024 |
Pre-clinical Evaluation of Novel Inorganic Compounds as Potential Anticancer Therapies SL Shepherd University of Huddersfield, 2018 | | 2018 |
Functionalised peptidomimetic metallohelices H Song University of Warwick, 2018 | | 2018 |
Data for Anticancer metallohelices: nanomolar potency and high selectivity RA Kaner, SA Allison, AD Faulkner, DH Simpson, NR Waterfield, ... University of Warwick. Science. Chemistry. Scott Group., 2015 | | 2015 |
Hypoxia Sensitive Metal b-Ketoiminato Complexes Showing Induced Single Strand DNA Breaks and Cancer Cell Death by Apoptosis RM Lord, AJ Hebden, CM Pask, IR Henderson, SJ Allison, SL Shepherd, ... | | |