Commensal Bifidobacterium promotes antitumor immunity and facilitates anti–PD-L1 efficacy A Sivan, L Corrales, N Hubert, JB Williams, K Aquino-Michaels, ZM Earley, ... Science 350 (6264), 1084-1089, 2015 | 3855 | 2015 |
Up-regulation of PD-L1, IDO, and Tregs in the melanoma tumor microenvironment is driven by CD8+ T cells S Spranger, RM Spaapen, Y Zha, J Williams, Y Meng, TT Ha, TF Gajewski Science translational medicine 5 (200), 200ra116-200ra116, 2013 | 1917 | 2013 |
A requisite role for induced regulatory T cells in tolerance based on expanding antigen receptor diversity D Haribhai, JB Williams, S Jia, D Nickerson, EG Schmitt, B Edwards, ... Immunity 35 (1), 109-122, 2011 | 546 | 2011 |
Cancer immunotherapy targets based on understanding the T cell-inflamed versus non-T cell-inflamed tumor microenvironment TF Gajewski, L Corrales, J Williams, B Horton, A Sivan, S Spranger Tumor immune microenvironment in cancer progression and cancer therapy, 19-31, 2017 | 288 | 2017 |
Thymic regulatory T cells arise via two distinct developmental programs DL Owen, SA Mahmud, LE Sjaastad, JB Williams, JA Spanier, ... Nature immunology 20 (2), 195-205, 2019 | 246 | 2019 |
The EGR2 targets LAG-3 and 4-1BB describe and regulate dysfunctional antigen-specific CD8+ T cells in the tumor microenvironment JB Williams, BL Horton, Y Zheng, Y Duan, JD Powell, TF Gajewski Journal of Experimental Medicine 214 (2), 381-400, 2017 | 219 | 2017 |
Intratumoral CD8+ T-cell Apoptosis Is a Major Component of T-cell Dysfunction and Impedes Antitumor Immunity BL Horton, JB Williams, A Cabanov, S Spranger, TF Gajewski Cancer immunology research 6 (1), 14-24, 2018 | 166 | 2018 |
Antagonism of the STING pathway via activation of the AIM2 inflammasome by intracellular DNA L Corrales, SR Woo, JB Williams, SM McWhirter, TW Dubensky, ... The Journal of Immunology 196 (7), 3191-3198, 2016 | 148 | 2016 |
IL-10 produced by induced regulatory T cells (iTregs) controls colitis and pathogenic ex-iTregs during immunotherapy EG Schmitt, D Haribhai, JB Williams, P Aggarwal, S Jia, LM Charbonnier, ... The Journal of Immunology 189 (12), 5638-5648, 2012 | 111 | 2012 |
Tumor heterogeneity and clonal cooperation influence the immune selection of IFN-γ-signaling mutant cancer cells JB Williams, S Li, EF Higgs, A Cabanov, X Wang, H Huang, TF Gajewski Nature communications 11 (1), 602, 2020 | 107 | 2020 |
The TCR repertoires of regulatory and conventional T cells specific for the same foreign antigen are distinct LM Relland, JB Williams, GN Relland, D Haribhai, J Ziegelbauer, ... The Journal of Immunology 189 (7), 3566-3574, 2012 | 34 | 2012 |
Epigenetic Control of Cdkn2a.Arf Protects Tumor-Infiltrating Lymphocytes from Metabolic Exhaustion B Koss, BD Shields, EM Taylor, AJ Storey, SD Byrum, AJ Gies, ... Cancer research 80 (21), 4707-4719, 2020 | 27 | 2020 |
Distinct graft-specific TCR avidity profiles during acute rejection and tolerance ML Miller, CM McIntosh, JB Williams, Y Wang, MK Hollinger, NJ Isaad, ... Cell reports 24 (8), 2112-2126, 2018 | 20 | 2018 |
Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells C Martins, M Silva, E Rasbach, P Singh, Y Itoh, JB Williams, E Statham, ... Scientific reports 12 (1), 12491, 2022 | 10 | 2022 |
31st Annual Meeting and Associated Programs of the Society for Immunotherapy of Cancer (SITC 2016): part one: National Harbor, MD, USA. 9-13 November 2016 A Lundqvist, V van Hoef, X Zhang, E Wennerberg, J Lorent, K Witt, ... Journal for immunotherapy of cancer 4, 1-106, 2016 | 8 | 2016 |
A Role for the Library in Public Research: The Global COVID-19 Dashboard M Blake, RC Murray, J Williams, J Gara, D Belros, S Choudhury portal: Libraries and the Academy 22 (1), 7-25, 2022 | 4 | 2022 |
Resident memory T cells in the tumor microenvironment JB Williams, TS Kupper Tumor Microenvironment: Hematopoietic Cells–Part B, 39-68, 2020 | 4 | 2020 |
Dysfunctional antigen-specific cd8+ t cells in the tumor microenvironment T Gajewski, J Williams, B Horton US Patent 11,566,077, 2023 | 2 | 2023 |
LAG-3 and 4-1BB identify dysfunctional antigen-specific T cells in the tumor microenvironment and combinatorial LAG-3/4-1BB targeting gives synergistic tumor control JB Williams, B Horton, Y Zheng, TF Gajewski Journal for ImmunoTherapy of Cancer 3, 1-1, 2015 | 1 | 2015 |
659 Blocking cytokine IL-1 with anakinra for the prevention of cytokine release syndrome in COVID-19 E Soule, J Williams, M Piesche Journal for ImmunoTherapy of Cancer 8 (Suppl 3), 2020 | | 2020 |