Convergent loss of PTEN leads to clinical resistance to a PI (3) Kα inhibitor D Juric, P Castel, M Griffith, OL Griffith, HH Won, H Ellis, SH Ebbesen, ... Nature 518 (7538), 240-244, 2015 | 612 | 2015 |
CIViC is a community knowledgebase for expert crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, JF McMichael, AC Coffman, AM Danos, ... Nature genetics 49 (2), 170-174, 2017 | 592 | 2017 |
DGIdb 2.0: mining clinically relevant drug–gene interactions AH Wagner, AC Coffman, BJ Ainscough, NC Spies, ZL Skidmore, ... Nucleic acids research 44 (D1), D1036-D1044, 2016 | 404 | 2016 |
High-performance web services for querying gene and variant annotation J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ... Genome biology 17, 1-7, 2016 | 199 | 2016 |
Informatics for RNA sequencing: a web resource for analysis on the cloud M Griffith, JR Walker, NC Spies, BJ Ainscough, OL Griffith PLoS computational biology 11 (8), e1004393, 2015 | 162 | 2015 |
Genome-wide association study of CSF levels of 59 Alzheimer's disease candidate proteins: significant associations with proteins involved in amyloid processing and inflammation JSK Kauwe, MH Bailey, PG Ridge, R Perry, ME Wadsworth, KL Hoyt, ... PLoS genetics 10 (10), e1004758, 2014 | 142 | 2014 |
The prognostic effects of somatic mutations in ER-positive breast cancer OL Griffith, NC Spies, M Anurag, M Griffith, J Luo, D Tu, B Yeo, J Kunisaki, ... Nature communications 9 (1), 3476, 2018 | 139 | 2018 |
DoCM: a database of curated mutations in cancer BJ Ainscough, M Griffith, AC Coffman, AH Wagner, J Kunisaki, ... Nature methods 13 (10), 806-807, 2016 | 124 | 2016 |
Organizing knowledge to enable personalization of medicine in cancer BM Good, BJ Ainscough, JF McMichael, AI Su, OL Griffith Genome biology 15, 1-9, 2014 | 108 | 2014 |
Standard operating procedure for somatic variant refinement of sequencing data with paired tumor and normal samples EK Barnell, P Ronning, KM Campbell, K Krysiak, BJ Ainscough, LM Sheta, ... Genetics in Medicine 21 (4), 972-981, 2019 | 92 | 2019 |
Genome modeling system: a knowledge management platform for genomics M Griffith, OL Griffith, SM Smith, A Ramu, MB Callaway, AM Brummett, ... PLoS computational biology 11 (7), e1004274, 2015 | 90 | 2015 |
Phosphorylated tau-Aβ42 ratio as a continuous trait for biomarker discovery for early-stage Alzheimer’s disease in multiplex immunoassay panels of cerebrospinal fluid O Harari, C Cruchaga, JSK Kauwe, BJ Ainscough, K Bales, EH Pickering, ... Biological psychiatry 75 (9), 723-731, 2014 | 88 | 2014 |
A deep learning approach to automate refinement of somatic variant calling from cancer sequencing data BJ Ainscough, EK Barnell, P Ronning, KM Campbell, AH Wagner, ... Nature genetics 50 (12), 1735-1743, 2018 | 84 | 2018 |
Comprehensive genomic analysis reveals FLT3 activation and a therapeutic strategy for a patient with relapsed adult B-lymphoblastic leukemia M Griffith, OL Griffith, K Krysiak, ZL Skidmore, MJ Christopher, JM Klco, ... Experimental hematology 44 (7), 603-613, 2016 | 56 | 2016 |
Molecular phylogenetics of the burrowing crayfish genus Fallicambarus (Decapoda: Cambaridae) BJ Ainscough, JW Breinholt, HW Robison, KA Crandall Zoologica Scripta 42 (3), 306-316, 2013 | 29 | 2013 |
CIViCdb 2022: evolution of an open-access cancer variant interpretation knowledgebase K Krysiak, AM Danos, J Saliba, JF McMichael, AC Coffman, S Kiwala, ... Nucleic acids research 51 (D1), D1230-D1241, 2023 | 18 | 2023 |
CIViC: a knowledgebase for expert-crowdsourcing the clinical interpretation of variants in cancer M Griffith, NC Spies, K Krysiak, AC Coffman, JF McMichael, BJ Ainscough, ... bioRxiv, 072892, 2016 | 7 | 2016 |
A community approach to the cancer-variant-interpretation bottleneck K Krysiak, AM Danos, S Kiwala, JF McMichael, AC Coffman, EK Barnell, ... Nature cancer 3 (5), 522-525, 2022 | 5 | 2022 |
MyGene. info and MyVariant. info: gene and variant annotation query services J Xin, A Mark, C Afrasiabi, G Tsueng, M Juchler, N Gopal, GS Stupp, ... bioRxiv, 035667, 2015 | 4 | 2015 |
Machine Learning to Predict Success of Response for Patients Treated with a Procedureless Balloon R Sankhe, MBA Chris Martinez MS, J Feldgoise Obesity 31, 158-158, 2023 | 1 | 2023 |