| Glutathione and thioredoxin antioxidant pathways synergize to drive cancer initiation and progression IS Harris, AE Treloar, S Inoue, M Sasaki, C Gorrini, KC Lee, KY Yung, ... Cancer cell 27 (2), 211-222, 2015 | 1017 | 2015 |
| BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival C Gorrini, PS Baniasadi, IS Harris, J Silvester, S Inoue, B Snow, PA Joshi, ... Journal of Experimental Medicine 210 (8), 1529-1544, 2013 | 325 | 2013 |
| A Sleeping Beauty forward genetic screen identifies new genes and pathways driving osteosarcoma development and metastasis BS Moriarity, GM Otto, EP Rahrmann, SK Rathe, NK Wolf, MT Weg, ... Nature genetics 47 (6), 615-624, 2015 | 266 | 2015 |
| Loss of the Timp gene family is sufficient for the acquisition of the CAF-like cell state M Shimoda, S Principe, HW Jackson, V Luga, H Fang, SD Molyneux, ... Nature cell biology 16 (9), 889-901, 2014 | 225 | 2014 |
| Estrogen controls the survival of BRCA1-deficient cells via a PI3K–NRF2-regulated pathway C Gorrini, BP Gang, C Bassi, A Wakeham, SP Baniasadi, Z Hao, WY Li, ... Proceedings of the National Academy of Sciences 111 (12), 4472-4477, 2014 | 148 | 2014 |
| Notch activation by the metalloproteinase ADAM17 regulates myeloproliferation and atopic barrier immunity by suppressing epithelial cytokine synthesis A Murthy, YW Shao, SR Narala, SD Molyneux, JC Zúñiga-Pflücker, ... Immunity 36 (1), 105-119, 2012 | 131 | 2012 |
| Prkar1a is an osteosarcoma tumor suppressor that defines a molecular subclass in mice SD Molyneux, MA Di Grappa, AG Beristain, TD McKee, DH Wai, ... The Journal of clinical investigation 120 (9), 3310-3325, 2010 | 112 | 2010 |
| PKA signaling drives mammary tumorigenesis through Src AG Beristain, SD Molyneux, PA Joshi, NC Pomroy, MA Di Grappa, ... Oncogene 34 (9), 1160-1173, 2015 | 101 | 2015 |
| RANKL blockade prevents and treats aggressive osteosarcomas Y Chen, MA Di Grappa, SD Molyneux, TD McKee, P Waterhouse, ... Science translational medicine 7 (317), 317ra197-317ra197, 2015 | 91 | 2015 |
| Cross-species genomics identifies DLG2 as a tumor suppressor in osteosarcoma YW Shao, GA Wood, J Lu, QL Tang, J Liu, S Molyneux, Y Chen, H Fang, ... Oncogene 38 (2), 291-298, 2019 | 80 | 2019 |
| Human somatic cell mutagenesis creates genetically tractable sarcomas SD Molyneux, PD Waterhouse, D Shelton, YW Shao, CM Watling, ... Nature genetics 46 (9), 964-972, 2014 | 36 | 2014 |
| Genome-wide comparison of matched canine osteosarcoma primary tumours and metastases by array comparative genomic hybridization. JHW Liu, YW Shao, SD Molyneux, R Khokha, GA Wood Cancer Research 73 (8_Supplement), 398-398, 2013 | | 2013 |
| Abstract A6: Dissecting mechanisms of RANKL dependency in osteosarcoma AG Beristain, S Molyneux, MA Di Grappa, R Khokha Cancer Research 69 (23_Supplement), A6-A6, 2009 | | 2009 |