Multiple independent loci at chromosome 15q25. 1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD NL Saccone, RC Culverhouse, TH Schwantes-An, DS Cannon, X Chen, ... PLoS genetics 6 (8), e1001053, 2010 | 404 | 2010 |
Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder Z Zhao, J Xu, J Chen, S Kim, M Reimers, SA Bacanu, H Yu, C Liu, J Sun, ... Molecular psychiatry 20 (5), 563-572, 2015 | 166 | 2015 |
Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of … TH Schwantes-An, J Zhang, LS Chen, SM Hartz, RC Culverhouse, ... Behavior genetics 46, 151-169, 2016 | 134 | 2016 |
Anti-amyloid monoclonal antibodies for the treatment of Alzheimer’s disease J Cummings, AML Osse, D Cammann, J Powell, J Chen BioDrugs 38 (1), 5-22, 2024 | 125 | 2024 |
Variants in nicotinic acetylcholine receptors α5 and α3 increase risks to nicotine dependence X Chen, J Chen, VS Williamson, SS An, JM Hettema, SH Aggen, ... American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 150 …, 2009 | 124 | 2009 |
A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder J Duan, J Shi, A Fiorentino, C Leites, X Chen, W Moy, J Chen, ... The American Journal of Human Genetics 95 (6), 744-753, 2014 | 117 | 2014 |
Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers SM Hartz, SE Short, NL Saccone, R Culverhouse, LS Chen, ... Archives of general psychiatry 69 (8), 854-860, 2012 | 97 | 2012 |
Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence DB Hancock, GW Reginsson, NC Gaddis, X Chen, NL Saccone, SM Lutz, ... Translational psychiatry 5 (10), e651-e651, 2015 | 96 | 2015 |
Genetic correlations between Alzheimer’s disease and gut microbiome genera D Cammann, Y Lu, MJ Cummings, ML Zhang, JM Cue, J Do, J Ebersole, ... Scientific Reports 13 (1), 5258, 2023 | 92 | 2023 |
GWA study data mining and independent replication identify cardiomyopathy-associated 5 (CMYA5) as a risk gene for schizophrenia X Chen, G Lee, BS Maher, AH Fanous, J Chen, Z Zhao, A Guo, ... Molecular psychiatry 16 (11), 1117-1129, 2011 | 91 | 2011 |
Genetic relationship between schizophrenia and nicotine dependence J Chen, SA Bacanu, H Yu, Z Zhao, P Jia, KS Kendler, HR Kranzler, ... Scientific reports 6 (1), 25671, 2016 | 86 | 2016 |
RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia J Xu, J Sun, J Chen, L Wang, A Li, M Helm, SL Dubovsky, SA Bacanu, ... BMC genomics 13, 1-10, 2012 | 82 | 2012 |
Genetic studies of schizophrenia: an update J Chen, F Cao, L Liu, L Wang, X Chen Neuroscience bulletin 31, 87-98, 2015 | 62 | 2015 |
Jun N-terminal kinase promotes proliferation of immature erythroid cells and erythropoietin-dependent cell lines SM Jacobs-Helber, ST Sawyer Blood 104 (3), 696-703, 2004 | 59 | 2004 |
Use of wastewater surveillance for early detection of Alpha and Epsilon SARS-CoV-2 variants of concern and estimation of overall COVID-19 infection burden V Vo, RL Tillett, K Papp, S Shen, R Gu, A Gorzalski, D Siao, R Markland, ... Science of the Total Environment 835, 155410, 2022 | 53 | 2022 |
Genome-wide meta-analysis of cotinine levels in cigarette smokers identifies locus at 4q13. 2 JJ Ware, X Chen, J Vink, A Loukola, C Minica, R Pool, Y Milaneschi, ... Scientific reports 6 (1), 20092, 2016 | 53 | 2016 |
Tumor necrosis factor-alpha expressed constitutively in erythroid cells or induced by erythropoietin has negative and stimulatory roles in normal erythropoiesis and erythroleukemia SM Jacobs-Helber, K Roh, D Bailey, EN Dessypris, JJ Ryan, J Chen, ... Blood, The Journal of the American Society of Hematology 101 (2), 524-531, 2003 | 53 | 2003 |
The interleukin 3 gene (IL3) contributes to human brain volume variation by regulating proliferation and survival of neural progenitors X Luo, M Li, L Huang, K Nho, M Deng, Q Chen, DR Weinberger, ... PloS one 7 (11), e50375, 2012 | 47 | 2012 |
Inhibition of monoacylglycerol lipase reduces nicotine withdrawal PP Muldoon, J Chen, JL Harenza, RA Abdullah, LJ Sim‐Selley, ... British journal of pharmacology 172 (3), 869-882, 2015 | 43 | 2015 |
Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder KJ Jackson, AH Fanous, J Chen, KS Kendler, X Chen Psychiatric genetics 23 (1), 20-28, 2013 | 43 | 2013 |