Gerald I Shulman

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Rachel J. PerryAssociate Professor, Yale UniversityE-mailová adresa ověřena na: yale.edu
Douglas E BefroyYaleE-mailová adresa ověřena na: yale.edu
Hui-Young LeeYale UniversityE-mailová adresa ověřena na: gachon.ac.kr
A BirkenfeldE-mailová adresa ověřena na: med.uni-tuebingen.de
sonia caprioProfessor at Yale UniversityE-mailová adresa ověřena na: yale.edu
François JornayvazProfessor of MedicineE-mailová adresa ověřena na: hcuge.ch
Max C. PetersenDivision of Endocrinology, Metabolism, & Lipid Research, Washington University in St. LouisE-mailová adresa ověřena na: wustl.edu
Graeme MasonYale UniversityE-mailová adresa ověřena na: yale.edu
Martin KrššákMedical University of ViennaE-mailová adresa ověřena na: meduniwien.ac.at
Gianluca PerseghinUniversità degli Studi di Milano Bicocca & Policlinico di MonzaE-mailová adresa ověřena na: unimib.it
Bruce M. SpiegelmanStanley J. Korsmeyer Professor, Harvard Medical School and Dana-Farber Cancer InstituteE-mailová adresa ověřena na: dfci.harvard.edu
Tamas L. HorvathYale UniversityE-mailová adresa ověřena na: yale.edu
Raynald BergeronAssociate professor of Kinesiology, University of MontrealE-mailová adresa ověřena na: umontreal.ca
Blas GuigniDefense Centers for Public HealthE-mailová adresa ověřena na: armywarcollege.edu
Chunli YuIcahn School of Medicine at Mount SinaiE-mailová adresa ověřena na: mssm.edu
Ralph DeFronzoUTHSCSAE-mailová adresa ověřena na: uthscsa.edu
Stephen PrevisMerckE-mailová adresa ověřena na: merck.com
David FrederickPostdoctoral fellow, Perelman School of Medicine, University of PennsylvaniaE-mailová adresa ověřena na: mail.med.upenn.edu
Young-Bum KimHarvard Medical SchoolE-mailová adresa ověřena na: bidmc.harvard.edu
C. Ronald KahnJoslin Diabetes Center and Harvard Medical SchoolE-mailová adresa ověřena na: joslin.harvard.edu

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Gerald I Shulman

Yale School of Medicine/Howard Hughes Medical Institute

E-mailová adresa ověřena na: yale.edu - Domovská stránka

mitochondrial metabolism type 2 diabetes insulin resistance gluconeogenesis glycogen metabolism


Název Seřadit podle citací Seřadit podle roku Seřadit podle názvu	Citace Citace	Rok
Cellular mechanisms of insulin resistance GI Shulman The Journal of clinical investigation 106 (2), 171-176, 2000	4042	2000
Mechanisms of insulin action and insulin resistance MC Petersen, GI Shulman Physiological reviews, 2018	2933	2018
Mitochondrial dysfunction and type 2 diabetes BB Lowell, GI Shulman Science 307 (5708), 384-387, 2005	2789	2005
Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes KF Petersen, S Dufour, D Befroy, R Garcia, GI Shulman New England Journal of Medicine 350 (7), 664-671, 2004	2743	2004
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity J Henao-Mejia, E Elinav, C Jin, L Hao, WZ Mehal, T Strowig, CA Thaiss, ... nature 482 (7384), 179-185, 2012	2734	2012
Mechanisms for insulin resistance: common threads and missing links VT Samuel, GI Shulman Cell 148 (5), 852-871, 2012	2694	2012
Mitochondrial dysfunction in the elderly: possible role in insulin resistance KF Petersen, D Befroy, S Dufour, J Dziura, C Ariyan, DL Rothman, ... Science 300 (5622), 1140-1142, 2003	2653	2003
Type 2 diabetes mellitus RA DeFronzo, E Ferrannini, L Groop, RR Henry, WH Herman, JJ Holst, ... Nature reviews Disease primers 1 (1), 1-22, 2015	2620	2015
Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKBβ) H Cho, J Mu, JK Kim, JL Thorvaldsen, Q Chu, EB Crenshaw III, ... Science 292 (5522), 1728-1731, 2001	2398	2001
Disruption of IRS-2 causes type 2 diabetes in mice DJ Withers, JS Gutierrez, H Towery, DJ Burks, JM Ren, S Previs, Y Zhang, ... Nature 391 (6670), 900-904, 1998	2177	1998
Mechanism of free fatty acid-induced insulin resistance in humans M Roden, TB Price, G Perseghin, KF Petersen, DL Rothman, GW Cline, ... The Journal of clinical investigation 97 (12), 2859-2865, 1996	2166	1996
Free fatty acids in obesity and type 2 diabetes: defining their role in the development of insulin resistance and β‐cell dysfunction G Boden, GI Shulman European journal of clinical investigation 32, 14-23, 2002	2031	2002
Mechanism by which fatty acids inhibit insulin activation of insulin receptor substrate-1 (IRS-1)-associated phosphatidylinositol 3-kinase activity in muscle C Yu, Y Chen, GW Cline, D Zhang, H Zong, Y Wang, R Bergeron, JK Kim, ... Journal of Biological Chemistry 277 (52), 50230-50236, 2002	1983	2002
Mechanism of hepatic insulin resistance in non-alcoholic fatty liver disease VT Samuel, ZX Liu, X Qu, BD Elder, S Bilz, D Befroy, AJ Romanelli, ... Journal of Biological Chemistry 279 (31), 32345-32353, 2004	1769	2004
Effects of free fatty acids on glucose transport and IRS-1–associated phosphatidylinositol 3-kinase activity A Dresner, D Laurent, M Marcucci, ME Griffin, S Dufour, GW Cline, ... The Journal of clinical investigation 103 (2), 253-259, 1999	1767	1999
Free fatty acid-induced insulin resistance is associated with activation of protein kinase C theta and alterations in the insulin signaling cascade. ME Griffin, MJ Marcucci, GW Cline, K Bell, N Barucci, D Lee, LJ Goodyear, ... Diabetes 48 (6), 1270-1274, 1999	1735	1999
Adipose-selective targeting of the GLUT4 gene impairs insulin action in muscle and liver ED Abel, O Peroni, JK Kim, YB Kim, O Boss, E Hadro, T Minnemann, ... Nature 409 (6821), 729-733, 2001	1663	2001
Loss of insulin signaling in hepatocytes leads to severe insulin resistance and progressive hepatic dysfunction MD Michael, RN Kulkarni, C Postic, SF Previs, GI Shulman, ... Molecular cell 6 (1), 87-97, 2000	1655	2000
Intramyocellular lipid concentrations are correlated with insulin sensitivity in humans: a 1H NMR spectroscopy study M Krssak, K Falk Petersen, A Dresner, L DiPietro, SM Vogel, DL Rothman, ... Diabetologia 42, 113-116, 1999	1652	1999
Quantitation of muscle glycogen synthesis in normal subjects and subjects with non-insulin-dependent diabetes by 13C nuclear magnetic resonance spectroscopy GI Shulman, DL Rothman, T Jue, P Stein, RA DeFronzo, RG Shulman New England Journal of Medicine 322 (4), 223-228, 1990	1645	1990

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