Manganese promotes the aggregation and prion-like cell-to-cell exosomal transmission of α-synuclein DS Harischandra, D Rokad, ML Neal, S Ghaisas, S Manne, S Sarkar, ... Science signaling 12 (572), eaau4543, 2019 | 164 | 2019 |
α‐Synuclein real‐time quaking‐induced conversion in the submandibular glands of Parkinson's disease patients S Manne, N Kondru, H Jin, V Anantharam, X Huang, A Kanthasamy, ... Movement Disorders 35 (2), 268-278, 2020 | 133 | 2020 |
Blinded RT‐QuIC analysis of α‐Synuclein biomarker in skin tissue from Parkinson's disease patients S Manne, N Kondru, H Jin, GE Serrano, V Anantharam, A Kanthasamy, ... Movement Disorders 35 (12), 2230-2239, 2020 | 132 | 2020 |
Kv1. 3 modulates neuroinflammation and neurodegeneration in Parkinson’s disease S Sarkar, HM Nguyen, E Malovic, J Luo, M Langley, BN Palanisamy, ... The Journal of Clinical Investigation 130 (8), 4195-4212, 2020 | 123 | 2020 |
Ultrasensitive detection of aggregated α-synuclein in glial cells, human cerebrospinal fluid, and brain tissue using the RT-QuIC assay: new high-throughput neuroimmune … S Manne, N Kondru, M Hepker, H Jin, V Anantharam, M Lewis, X Huang, ... Journal of Neuroimmune Pharmacology 14, 423-435, 2019 | 84 | 2019 |
Experimental transmission of the chronic wasting disease agent to swine after oral or intracranial inoculation SJ Moore, MH West Greenlee, N Kondru, S Manne, JD Smith, RA Kunkle, ... Journal of virology 91 (19), 10.1128/jvi. 00926-17, 2017 | 73 | 2017 |
Genetic diseases conferring resistance to infectious diseases IC Withrock, SJ Anderson, MA Jefferson, GR McCormack, ... Genes & diseases 2 (3), 247-254, 2015 | 54 | 2015 |
The AD tau core spontaneously self-assembles and recruits full-length tau to filaments Y Carlomagno, S Manne, M DeTure, M Prudencio, YJ Zhang, ... Cell reports 34 (11), 2021 | 53 | 2021 |
Temporal resolution of misfolded prion protein transport, accumulation, glial activation, and neuronal death in the retinas of mice inoculated with scrapie MHW Greenlee, M Lind, R Kokemuller, N Mammadova, N Kondru, ... The American journal of pathology 186 (9), 2302-2309, 2016 | 40 | 2016 |
Integrated organotypic slice cultures and RT-QuIC (OSCAR) assay: implications for translational discovery in protein misfolding diseases N Kondru, S Manne, J Greenlee, H West Greenlee, V Anantharam, ... Scientific reports 7 (1), 43155, 2017 | 35 | 2017 |
Cross-validation of the RT-QuIC assay for the antemortem detection of chronic wasting disease in elk NJ Haley, R Donner, DM Henderson, J Tennant, EA Hoover, M Manca, ... Prion 14 (1), 47-55, 2020 | 25 | 2020 |
PKC delta activation promotes endoplasmic reticulum stress (ERS) and NLR family pyrin domain-containing 3 (NLRP3) inflammasome activation subsequent to asynuclein-induced … M Samidurai, BN Palanisamy, A Bargues-Carot, M Hepker, N Kondru, ... Frontiers in Aging Neuroscience 13, 661505, 2021 | 23 | 2021 |
Ante-mortem detection of chronic wasting disease in recto-anal mucosa-associated lymphoid tissues from elk (Cervus elaphus nelsoni) using real-time quaking … S Manne, N Kondru, T Nichols, A Lehmkuhl, B Thomsen, R Main, ... Prion 11 (6), 415-430, 2017 | 21 | 2017 |
Off-Target drug effects resulting in altered gene expression events with epigenetic and Quasi-Epigenetic origins SJ Anderson, KM Feye, GR Schmidt-McCormack, E Malovic, ... Pharmacological research 107, 229-233, 2016 | 16 | 2016 |
An Ex Vivo Brain Slice Culture Model of Chronic Wasting Disease: Implications for Disease Pathogenesis and Therapeutic Development N Kondru, S Manne, R Kokemuller, J Greenlee, MHW Greenlee, T Nichols, ... Scientific reports 10 (1), 7640, 2020 | 14 | 2020 |
Pick’s disease, seeding an answer to the clinical diagnosis conundrum N Tamvaka, S Manne, N Kondru, OA Ross Biomedicines 11 (6), 1646, 2023 | 8 | 2023 |
Manganese exposure augments misfolded α‐synuclein‐induced proinflammatory M1 microglial phenotype and inflammasome activation N Kondru, S Manne, M Hepker, E Malovic, H Jin, V Anantram, ... The FASEB Journal 33 (S1), 505.7-505.7, 2019 | 2 | 2019 |
Manganese exposure enhances the release of misfolded α-synuclein via exosomes by impairing endosomal trafficking and protein degradation mechanisms D Rokad, DS Harischandra, M Samidurai, YT Chang, J Luo, V Lawana, ... International journal of molecular sciences 25 (22), 12207, 2024 | 1 | 2024 |
MANGANESE ACCELERATES TEMPLATE-DRIVEN PRION PROTEIN SEEDING ACTIVITY IN CELLS AND SLICE CULTURE MODELS OF PRION DISEASE S Manne, N Kondru, H Jin, V Anantharam, A Kanthasamy, ... Development of diagnostic biomarkers for proteinopathies: Relevance for …, 2019 | 1 | 2019 |
Veterinary Considerations for the Theoretical Resurrection of Extinct Species Journal of Veterinary Science & Animal Husbandry 6 (3), 2018 | 1 | 2018 |